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The map label for this gene is mrdB [H]

Identifier: 148825688

GI number: 148825688

Start: 633847

End: 634962

Strand: Direct

Name: mrdB [H]

Synonym: CGSHiEE_03155

Alternate gene names: 148825688

Gene position: 633847-634962 (Clockwise)

Preceding gene: 148825687

Following gene: 148825689

Centisome position: 34.96

GC content: 38.53

Gene sequence:

>1116_bases
ATGGAAGATAAAATCCCTTTTTGGTTGCGTGTTTGGCAACGTTTGCATATTGATTTTTGGCTGTTTATCGGACTTCTTGC
AATAACTGCTTATGGTATGCTGGTGTTATATAGTGCATCAGGTGCCAGTGAAACGATGTTTAATAGCCGAATTATTCAGG
TCTTACTTGGATTTATTGTTATGCTGTTAATGGCTCAATTTCCACCAAGATTTTACCAACGCATCGCACCTTATCTTTAT
TTAATTGGTTTTGTGTTATTGATCTTGGTAGATGTTATTGGTACGACAAGTAAAGGTGCGCAGCGTTGGCTTGATCTTGG
ATTTATTCGTTTTCAACCCTCTGAAATTGTAAAACTTGCTGTGCCATTAATGGTGGCGGTATATTTAGGTAATCGTCCGC
TTCCACCTAAATTAAGTGAAACATTTATAGCGATTGCAATGATTCTACTGCCAACATTGCTTGTGGCGATTCAGCCTGAT
TTAGGCACAGCAATTTTGGTCAGTGCGTCAGGTTTATTTGTCGTGTTTTTAGCAGGAATGAGCTGGTGGCTTATTTTAGC
TGCAGTGATTGGCTTAGCTGGATTTATTCCGATCATGTGGTTATATCTAATGCACGATTATCAACGCACTCGCGTTCTCA
CATTATTGGACCCAGAAAAAGATCCTCTCGGTGCTGGCTATCATATTTTACAATCAAAGATTGCGATTGGTTCTGGTGGA
TTAAGCGGAAAAGGCTGGATGCAGGGGACTCAATCACAATTAGAATTTTTGCCCGAACCTCATACAGATTTTATTTTTGC
GGTAATGGGCGAAGAGCACGGAATGATTGGTTTTTTGATTTTAATGGCGATTTACTTGTTTATTATTGTGCGAGGTTTAA
TGATTGCCGTAAATGCTCAAACTTCTTTTGGGCGTATTCTTGCTGGTGCAACAACATTAATTTTCTTTGTTTATGTATTT
GTGAATATTGGAATGGTAAGCGGAATTTTGCCTGTTGTGGGTGTGCCATTACCTTTATTTAGTTATGGTGGTACCTCTTA
TGTTGCGATTATGGCAAGTTTTGGTTTACTGATGTCTATTCATACGCATAAAAGTCAATTTATGAAAAGGAGCTAA

Upstream 100 bases:

>100_bases
GTGATGGATTACTATTTAAATCAGCGTTTACCACAAGTTGAAAAATATAATGTACCTATTCAGCAAAAAAAAGATTTGTC
ACAAGAGAGCGAACAAATAA

Downstream 100 bases:

>100_bases
TTTCATTTTTTTCTTTCTTAAAGAAAGAATAAATGAAAAGCGTTAATATTTTATGAAATTAAAAACTGGGTTAAATTTGA
CCGCACTTTTGCTATTTATG

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MEDKIPFWLRVWQRLHIDFWLFIGLLAITAYGMLVLYSASGASETMFNSRIIQVLLGFIVMLLMAQFPPRFYQRIAPYLY
LIGFVLLILVDVIGTTSKGAQRWLDLGFIRFQPSEIVKLAVPLMVAVYLGNRPLPPKLSETFIAIAMILLPTLLVAIQPD
LGTAILVSASGLFVVFLAGMSWWLILAAVIGLAGFIPIMWLYLMHDYQRTRVLTLLDPEKDPLGAGYHILQSKIAIGSGG
LSGKGWMQGTQSQLEFLPEPHTDFIFAVMGEEHGMIGFLILMAIYLFIIVRGLMIAVNAQTSFGRILAGATTLIFFVYVF
VNIGMVSGILPVVGVPLPLFSYGGTSYVAIMASFGLLMSIHTHKSQFMKRS

Sequences:

>Translated_371_residues
MEDKIPFWLRVWQRLHIDFWLFIGLLAITAYGMLVLYSASGASETMFNSRIIQVLLGFIVMLLMAQFPPRFYQRIAPYLY
LIGFVLLILVDVIGTTSKGAQRWLDLGFIRFQPSEIVKLAVPLMVAVYLGNRPLPPKLSETFIAIAMILLPTLLVAIQPD
LGTAILVSASGLFVVFLAGMSWWLILAAVIGLAGFIPIMWLYLMHDYQRTRVLTLLDPEKDPLGAGYHILQSKIAIGSGG
LSGKGWMQGTQSQLEFLPEPHTDFIFAVMGEEHGMIGFLILMAIYLFIIVRGLMIAVNAQTSFGRILAGATTLIFFVYVF
VNIGMVSGILPVVGVPLPLFSYGGTSYVAIMASFGLLMSIHTHKSQFMKRS
>Mature_371_residues
MEDKIPFWLRVWQRLHIDFWLFIGLLAITAYGMLVLYSASGASETMFNSRIIQVLLGFIVMLLMAQFPPRFYQRIAPYLY
LIGFVLLILVDVIGTTSKGAQRWLDLGFIRFQPSEIVKLAVPLMVAVYLGNRPLPPKLSETFIAIAMILLPTLLVAIQPD
LGTAILVSASGLFVVFLAGMSWWLILAAVIGLAGFIPIMWLYLMHDYQRTRVLTLLDPEKDPLGAGYHILQSKIAIGSGG
LSGKGWMQGTQSQLEFLPEPHTDFIFAVMGEEHGMIGFLILMAIYLFIIVRGLMIAVNAQTSFGRILAGATTLIFFVYVF
VNIGMVSGILPVVGVPLPLFSYGGTSYVAIMASFGLLMSIHTHKSQFMKRS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=358, Percent_Identity=62.8491620111732, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1786277, Length=355, Percent_Identity=35.4929577464789, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41149; Mature: 41149

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKIPFWLRVWQRLHIDFWLFIGLLAITAYGMLVLYSASGASETMFNSRIIQVLLGFIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
MLLMAQFPPRFYQRIAPYLYLIGFVLLILVDVIGTTSKGAQRWLDLGFIRFQPSEIVKLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHH
VPLMVAVYLGNRPLPPKLSETFIAIAMILLPTLLVAIQPDLGTAILVSASGLFVVFLAGM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHH
SWWLILAAVIGLAGFIPIMWLYLMHDYQRTRVLTLLDPEKDPLGAGYHILQSKIAIGSGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LSGKGWMQGTQSQLEFLPEPHTDFIFAVMGEEHGMIGFLILMAIYLFIIVRGLMIAVNAQ
CCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECC
TSFGRILAGATTLIFFVYVFVNIGMVSGILPVVGVPLPLFSYGGTSYVAIMASFGLLMSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
HTHKSQFMKRS
HHHHHHHHCCC
>Mature Secondary Structure
MEDKIPFWLRVWQRLHIDFWLFIGLLAITAYGMLVLYSASGASETMFNSRIIQVLLGFIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHH
MLLMAQFPPRFYQRIAPYLYLIGFVLLILVDVIGTTSKGAQRWLDLGFIRFQPSEIVKLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHH
VPLMVAVYLGNRPLPPKLSETFIAIAMILLPTLLVAIQPDLGTAILVSASGLFVVFLAGM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHH
SWWLILAAVIGLAGFIPIMWLYLMHDYQRTRVLTLLDPEKDPLGAGYHILQSKIAIGSGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LSGKGWMQGTQSQLEFLPEPHTDFIFAVMGEEHGMIGFLILMAIYLFIIVRGLMIAVNAQ
CCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECC
TSFGRILAGATTLIFFVYVFVNIGMVSGILPVVGVPLPLFSYGGTSYVAIMASFGLLMSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
HTHKSQFMKRS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]