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The map label for this gene is htpG [H]

Identifier: 148825623

GI number: 148825623

Start: 558424

End: 560304

Strand: Direct

Name: htpG [H]

Synonym: CGSHiEE_02775

Alternate gene names: 148825623

Gene position: 558424-560304 (Clockwise)

Preceding gene: 148825617

Following gene: 148825624

Centisome position: 30.8

GC content: 38.33

Gene sequence:

>1881_bases
ATGTCACAAAATCAAGAAACTCGCGGATTCCAATCTGAAGTCAAACAACTACTCCAATTAATGATTCATTCTTTGTACTC
TAACAAAGAAATTTTCTTACGTGAATTGATTTCTAATGCTTCTGATGCAGCAGATAAATTACGCTTTAAAGCACTTTCCA
ACCCTGCTTTATATGAAGGCGATGGCGACTTGCGTGTGCGTGTTAGCTTTGATGCGGATAAAGGCACTATCACAATTAGC
GATAACGGCATTGGCATGACCCGTGAGCAAGTCATCGATCATTTGGGTACGATTGCAAAATCAGGAACAAAAGAATTTTT
AACCGCACTTGGTCAAGATCAAGCAAAAAATAGCCAGCTTATTGGGCAATTTGGTGTGGGTTTTTATTCAGCTTTTATTG
TGGCAGATAAAGTGACTGTAAAAACCAGAGCAGCTGGCGAAGAGGCGGATAAAGCCGTACTTTGGGAATCTGCGGGTGAA
GGCGAATATTCTGTGGCGGATATTGAGAAAAAATCCCGTGGCACAGATGTGATTTTACATTTATGCGAAGATGAAAAAGA
ATTTTTAAACGAATGGCGTTTGCGTGAAATTATCGGTAAATATTCTGACCATATTGGCTTGCCAGTGGAAATGCTGACGA
AAGAATACGATGATGAAGGCAAAGAGTGCGGTGAAAAATGGGAGAAAATTAATAAATCCGATGCGCTTTGGACGCGTTCT
AAAAATGATGTGTCTGATGAGGAATACAAAGCGTTTTACAAACACTTAAGCCACGATTTTGCTGATCCTGTGACTTGGGC
GCATAACAAAGTTGAAGGAAATCAAGCATATACTAGTTTGCTTTATGTGCCAGCTAAAGCACCTTGGGATTTATTTAATC
GCGAACATAAACACGGCTTAAAACTTTATGTTCAACGTGTATTTATTATGGATGATGCTGAGCAATTTATGCCGAATTAT
CTACGTTTTATGCGTGGTTTAATCGATAGTAATGATTTGCCATTAAATGTATCTCGTGAAATTTTACAGGATAACAAAAT
TACGGCTGCATTACGCAAAGCATTAACTAAGCGTTCATTACAAATGCTAGAAAAATTAGCAAAAGATGATGCAGAAAAAT
ATCTTCAATTCTGGAAAGAGTTTGGTTTAGTCTTGAAAGAAGGTCCTACAGAAGATTTTGCTAACAAAGAAACTGTCGCG
AAGTTATTGCGTTTTGCTTCGACACATAATGATGGTAGTGAGCAAGCTGTCTCTTTAGAAGATTACATCTTGCGTATGAA
AGAGGGGCAAAAAGCTATCTATTACATTACAGCGGATAGTTATGTTGCAGCGAAAAATAGCCCACACTTGGAATTATTCA
ATAAAAAAGGCATTGAGGTTTTGTTGCTTTCCGATCGCATTGATGAATGGATGTTAAGCTATTTAACTGAATTTGACGGT
AAACAATTACAAAGTATCACGAAAGCAGATTTGGATTTAGGCGATTTAGCCGATAAAGAATCTGAAACACAAAAACAACA
AGATGAAGCCTTTGGTAGTTTTATTGAGCGTGTGAAAAACTTGCTTGGCGAACGGGTAAAAACGGTGCGTTTAACTCACA
ATTTAACGGATACACCAGCGGTGGTTTCTACGGATAACGATCAAATGACGACCCAAATGGCGAAATTGTTTGCAGCCGCA
GGGCAACCTGTACCAGAAGTAAAATACACATTTGAACTGAATCCAGAACATCATTTAGTGAAAAAAGTAGCGGATATTGC
AGATGAAACTGAATTTGCTGATTGGGTGGAACTGTTGCTTGAACAAGCTATGTTAGCAGAGCGCGGATCTTTGGAAAATC
CAGCTGCGTTTATTAAACGTATCAATAAGTTGTTAGGTTAA

Upstream 100 bases:

>100_bases
GTTTTTTTACCGCACTTTTCCTCTTAAATTCCCCTTGAAATCTTTCTTTTTATTCTTATATCTGTGACGTTCAATTTTTA
TCTTTATGAAGGAAAAAATT

Downstream 100 bases:

>100_bases
TTCATTTGAGATGAAGTAGCATAAGGGTTAAAATCCTCAATCTGATTAGATTGAGGATTTTTCTTTTTTAGGTGAAATAT
GATTACAGTTTACGGTATTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGTITIS
DNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGE
GEYSVADIEKKSRGTDVILHLCEDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
KNDVSDEEYKAFYKHLSHDFADPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNY
LRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPTEDFANKETVA
KLLRFASTHNDGSEQAVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAA
GQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Sequences:

>Translated_626_residues
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGTITIS
DNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGE
GEYSVADIEKKSRGTDVILHLCEDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
KNDVSDEEYKAFYKHLSHDFADPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNY
LRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPTEDFANKETVA
KLLRFASTHNDGSEQAVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAA
GQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
>Mature_625_residues
SQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGTITISD
NGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEG
EYSVADIEKKSRGTDVILHLCEDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRSK
NDVSDEEYKAFYKHLSHDFADPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNYL
RFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPTEDFANKETVAK
LLRFASTHNDGSEQAVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGK
QLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAAG
QPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=680, Percent_Identity=36.9117647058824, Blast_Score=421, Evalue=1e-117,
Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=35.5263157894737, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI155722983, Length=631, Percent_Identity=36.608557844691, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=37.0731707317073, Blast_Score=266, Evalue=5e-71,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=37.0731707317073, Blast_Score=264, Evalue=2e-70,
Organism=Escherichia coli, GI1786679, Length=623, Percent_Identity=74.9598715890851, Blast_Score=982, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=37.202380952381, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=671, Percent_Identity=35.9165424739195, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.179012345679, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=36.551724137931, Blast_Score=270, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=38.6094674556213, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=38.0882352941176, Blast_Score=450, Evalue=1e-127,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=36.6812227074236, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=37.8854625550661, Blast_Score=394, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=646, Percent_Identity=33.7461300309598, Blast_Score=343, Evalue=2e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71073; Mature: 70942

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQL
CCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
IGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILH
HHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCCCEEEE
LCEDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECC
KNDVSDEEYKAFYKHLSHDFADPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGL
CCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYLQFWKEFGLVLKEGPTEDFANKETVAKLLRFASTHNDGSEQAVSLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCHH
DYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPA
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
VVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLL
EEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
EQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQL
CCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
IGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILH
HHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCCCEEEE
LCEDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRS
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECC
KNDVSDEEYKAFYKHLSHDFADPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGL
CCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYLQFWKEFGLVLKEGPTEDFANKETVAKLLRFASTHNDGSEQAVSLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCHH
DYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPA
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
VVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLL
EEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
EQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8972900 [H]