Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 148825592

GI number: 148825592

Start: 509138

End: 510283

Strand: Direct

Name: nagA [H]

Synonym: CGSHiEE_02585

Alternate gene names: 148825592

Gene position: 509138-510283 (Clockwise)

Preceding gene: 148825591

Following gene: 148825595

Centisome position: 28.08

GC content: 38.48

Gene sequence:

>1146_bases
ATGAAATACGCATTAATTAATTGTGTAATTTACACAAAATATGATGTTTTACGTGATTTTGCTGTAATTATTAACGGTGA
AATTATTGAAGCGATAGTTCCCCAAGCTGAATTAGAAACAGGTATCAAAACCATTGATTTACAAGGTAATAATTTAACGG
CTGGTTTTATTGATCTGCAATTAAATGGCTGTGGTGGCGTGATGTTTAACGACCAAACTAGCGTTGAAACCTTGGAAATT
ATGCAGGAAACTAACTTAAAATCAGGTTGTACAAGTTTCCTTCCCACTTTTATTACCGCGCCCGATGAAAATATAAAAAG
TGCGGTAAAAATTATGCGTGAATATTTAAACAAGCATAAAAACCAAGCACTTGGTTTACATATTGAAGGGCCTTATCTCA
GCATTGAGAAAAAAGGTGTACACCGCCCCGAATATATTCGTGAAATTACGCCTGAAATGAAAGATTTCCTCTGCCAAAAT
GGTGATGTGATTACAAAAATGACCATTGCCGCAGAAAACCCAACCATTAACTATACGCCTGATTTTGTGAAAGCGGGCAT
TATTGTCTCTGTAGGCCATTCTAATGCCACTTATGAAGTGGCTAAAGCCGCATTCCACAAAGGCGCAACTTTTGCGACTC
ACTTGCATAATGCAATGTCGCCAATTAGTTCTGGACGTGAAATGGGCGTAGTGGGTGCAGTATTAGATTCTGATGTTTAC
ACTGGCATTATCGTCGATGGTGTGCATATCAATTACGGCAATGTTCGCATTGATAAAAAAATCAAAGGCGACAAACTTTG
TATTGTGACTGACTCTATTGCAGCGGCAGGCGCACCGCCAGAACTAGAAAGTTTTACCTTTGAGGGAAAAACAATTTATA
TCAAAGAAGGGCGTTGCTATGATGTGAATGGCACAATTGCTGGGGCATCAATCACAATGATGGAATCTATTAAAAATGCG
GTAGAATATGTTGAAATTCCTCTTGCGGAAGCCATTAGAATGAGTAACCTTTATCCTGCACGAGCAATTGGTATAGATGA
TCGTTTAGGTTCGGTAGAAAAAGGTAAGATAGCAAACTTAGCCGTGTTTACGCCAAATTACCAAGTAATCGGCACAGTAG
TAAACGGAAAGTGGAAAGAGAATTAA

Upstream 100 bases:

>100_bases
ATTCGCCCTATAATCACAAACAATCATAGGGCAAATTGTCCTTACGTTTAAGAGCAATATAGTTGCTATGTTAAACTGAT
GTTGATATTAGGAACAGAAT

Downstream 100 bases:

>100_bases
TAGTAAACACTTAAATAGTTAATTGATTTAAAAAATCTGTGATATATATCACAGATTTTTTATTAATATTTTGTTACTTA
TAAAATAGCCTAAATATTCA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKYALINCVIYTKYDVLRDFAVIINGEIIEAIVPQAELETGIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCQN
GDVITKMTIAAENPTINYTPDFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDVNGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKEN

Sequences:

>Translated_381_residues
MKYALINCVIYTKYDVLRDFAVIINGEIIEAIVPQAELETGIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCQN
GDVITKMTIAAENPTINYTPDFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDVNGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKEN
>Mature_381_residues
MKYALINCVIYTKYDVLRDFAVIINGEIIEAIVPQAELETGIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEI
MQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCQN
GDVITKMTIAAENPTINYTPDFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCYDVNGTIAGASITMMESIKNA
VEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKEN

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=430, Percent_Identity=28.6046511627907, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI224922791, Length=421, Percent_Identity=28.5035629453682, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1786892, Length=378, Percent_Identity=53.968253968254, Blast_Score=415, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17553768, Length=398, Percent_Identity=30.9045226130653, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=29.7157622739018, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=28.6783042394015, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41592; Mature: 41592

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYALINCVIYTKYDVLRDFAVIINGEIIEAIVPQAELETGIKTIDLQGNNLTAGFIDLQ
CCEEEEEEEEEEHHHHHHHEEEEECCHHHHHHCCHHHHHCCCEEEEECCCEEEEEEEEEE
LNGCGGVMFNDQTSVETLEIMQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHK
ECCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHCC
NQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCQNGDVITKMTIAAENPTINYTP
CCEEEEEECCCEEEEECCCCCCHHHHHHHCHHHHHHHHCCCCEEEEEEEEECCCEECCCC
DFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
HHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCY
EEEEEEEEEEECCCEEEECCCCCCEEEEEECCHHCCCCCCCCCCEEECCEEEEEECCEEE
DVNGTIAGASITMMESIKNAVEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANL
ECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEE
AVFTPNYQVIGTVVNGKWKEN
EEECCCCEEEEEEECCEECCC
>Mature Secondary Structure
MKYALINCVIYTKYDVLRDFAVIINGEIIEAIVPQAELETGIKTIDLQGNNLTAGFIDLQ
CCEEEEEEEEEEHHHHHHHEEEEECCHHHHHHCCHHHHHCCCEEEEECCCEEEEEEEEEE
LNGCGGVMFNDQTSVETLEIMQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHK
ECCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHCC
NQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCQNGDVITKMTIAAENPTINYTP
CCEEEEEECCCEEEEECCCCCCHHHHHHHCHHHHHHHHCCCCEEEEEEEEECCCEECCCC
DFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVY
HHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
TGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFEGKTIYIKEGRCY
EEEEEEEEEEECCCEEEECCCCCCEEEEEECCHHCCCCCCCCCCEEECCEEEEEECCEEE
DVNGTIAGASITMMESIKNAVEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANL
ECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEE
AVFTPNYQVIGTVVNGKWKEN
EEECCCCEEEEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]