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The map label for this gene is citT [C]

Identifier: 148825504

GI number: 148825504

Start: 390985

End: 392370

Strand: Direct

Name: citT [C]

Synonym: CGSHiEE_02015

Alternate gene names: 148825504

Gene position: 390985-392370 (Clockwise)

Preceding gene: 148825503

Following gene: 148825511

Centisome position: 21.57

GC content: 35.21

Gene sequence:

>1386_bases
ATGGGTGAGATGGCATCTTTAAGAAGTCATAAAAATGGCATTATTTTTATTTTAGATATTGTGCTGTTTTTTGTGTTATT
AAATGTATTACCTTTTGAACCAAAAGCTAATTCTGGTTTGGCATTATTAGCTTTTATCGCGGTGCTTTGGTTAAGTGAAG
CATTACACGTTACTATTACTGCATTATTAGTTCCACTTTTGGCTGTGGCATTGGGATTAGTTAGTACCAAACAAGCTTTA
GTTGGTTTTGCTGATCCGACAATATTTTTATTTTTTGGTGGCTTTTCCTTGGCGACGGCATTGCATATTCAAAAACTTGA
TAAATTGATTGCCAATAAGATTATGGCACTAGCATGCGGTAATTTATTTATCGCAGTTATTTATCTCTTTTTGATTACAG
CCTTTCTTTCTATGTGGATGAGTAACACGGCAACCGCTGCAATGATGTTACCCCTCGCCATGGGTATTTTAAGCCAGCTT
GATCGCGAAAAAGATCATAACACCTATGTGTTTGTGCTGTTAGGGATTGCTTACAGTGCATCAATTGGTGGTATGGGAAC
CCTTGTAGGAAGCCCACCAAATGCAATTGTAGCAAGTAATTTAAATTTAACTTTTTCTGATTGGTTATGGTATGGCTTAC
CAATAATGATTATTTTGTTGCCGTTGATGATTGGGATTCTTTATATTATTTTCAAACCAAAACTTCATCTCAATTTTGAA
CAGACCTTTGAAAATATTGAAATGAATCCTATGCGTATATTGACGTTTATTATTTTTTCAGTCATTGCTTTAACGTGGAT
ATTTAGCGGTAAAATTAATCCGTTTATTTCAGGATTACTAGGATTACAAAAAAACATTGCAAGTTTTGATAGTATCGTAG
CCTTATTGGCGGCAATTGTTATTTGTTCAACAGGCGTTGCAAGTTGGAAACAAATTCAATCAAATACCGATTGGGGCGTA
TTAATGCTTTTCGGTGGTGGATTAACATTAAGTGCGGTGTTGAAGGATTCTGGTGCAAGTAAAATTTTAGCGGATAGTAT
TGTTTTTATGATTGATGGACAACATTTCTATCTTATTGGTTTATTAGTTGCGGCGTTCATTATTTTCTTAACTGAATTTA
CTTCTAATACAGCGAGTGCGGCGTTACTTGTACCTATCTTTATTTCTATCGCTCAATCATTGGGTATGCCAGAAATTGGT
TTAGCATTAATTATTGGTATTGGTGCATCCTGTGCCTTTATGCTACCAGTAGCGACACCACCAAATGCGATTGTATTTGG
CTCTGGTCAAGTAAAACAAAGTGAAATGGTCAAAGTTGGTTTCTTACTGAATTTAGTCTGTGTTGTAGTTATTGCCACTA
TGGGTTATATGTTCTGGCTTAAATAA

Upstream 100 bases:

>100_bases
GTTGCTCTCGATCACATTTCTGAATATTGCTCGTTGCATCTTTATAACATTCATTTAACATTGAACCCTATTTAAGTGAT
AGCTCTAACGGAGGAACTTT

Downstream 100 bases:

>100_bases
TATAGAATTGTTTACTTTTAATAAATGATGATTGAAGATCATAAATTTAAACGTAAGAAGTACAATAAAGCCATTTAAAT
AAATGGGTTAAAGCAAATGA

Product: putative di- and tricarboxylate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MGEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTITALLVPLLAVALGLVSTKQAL
VGFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALACGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQL
DREKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFE
QTFENIEMNPMRILTFIIFSVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGV
LMLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIG
LALIIGIGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK

Sequences:

>Translated_461_residues
MGEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTITALLVPLLAVALGLVSTKQAL
VGFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALACGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQL
DREKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFE
QTFENIEMNPMRILTFIIFSVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGV
LMLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIG
LALIIGIGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK
>Mature_460_residues
GEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTITALLVPLLAVALGLVSTKQALV
GFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALACGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQLD
REKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFEQ
TFENIEMNPMRILTFIIFSVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGVL
MLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIGL
ALIIGIGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI31377715, Length=550, Percent_Identity=27.4545454545455, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI301069349, Length=496, Percent_Identity=28.2258064516129, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI58761541, Length=520, Percent_Identity=27.3076923076923, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI29171306, Length=503, Percent_Identity=26.8389662027833, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI19923838, Length=349, Percent_Identity=29.2263610315186, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI301069353, Length=356, Percent_Identity=27.247191011236, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4506979, Length=151, Percent_Identity=38.4105960264901, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI225637552, Length=151, Percent_Identity=38.4105960264901, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI225637549, Length=151, Percent_Identity=38.4105960264901, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301069346, Length=145, Percent_Identity=34.4827586206897, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI31795546, Length=356, Percent_Identity=23.0337078651685, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI219802232, Length=466, Percent_Identity=24.2489270386266, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1786829, Length=410, Percent_Identity=22.6829268292683, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551790, Length=506, Percent_Identity=24.1106719367589, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71988385, Length=485, Percent_Identity=27.6288659793814, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71989118, Length=495, Percent_Identity=26.6666666666667, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32564681, Length=484, Percent_Identity=24.1735537190083, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI32565804, Length=446, Percent_Identity=27.5784753363229, Blast_Score=131, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324340, Length=477, Percent_Identity=25.1572327044025, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322263, Length=458, Percent_Identity=24.8908296943231, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319885, Length=476, Percent_Identity=27.7310924369748, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45551633, Length=516, Percent_Identity=25.5813953488372, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281366409, Length=516, Percent_Identity=25.5813953488372, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17737623, Length=516, Percent_Identity=25.5813953488372, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24666468, Length=516, Percent_Identity=25.5813953488372, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI78706796, Length=472, Percent_Identity=24.7881355932203, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706798, Length=472, Percent_Identity=24.7881355932203, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281362114, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362112, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362116, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 49700; Mature: 49568

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTIT
CCCHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALLVPLLAVALGLVSTKQALVGFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALACG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQLDREKDHNTYVFVLLGIAYSA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHC
SIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFE
CCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHH
QTFENIEMNPMRILTFIIFSVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICSTGVASWKQIQSNTDWGVLMLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIG
HHHCCHHHHHHHHCCCCCEEEEEECCCCEEHHHHHCCCCCHHHHHCEEEEECCCHHHHHH
LLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIGLALIIGIGASCAFMLPVATP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCC
PNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTIT
CCHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALLVPLLAVALGLVSTKQALVGFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALACG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQLDREKDHNTYVFVLLGIAYSA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHC
SIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFE
CCCCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHH
QTFENIEMNPMRILTFIIFSVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICSTGVASWKQIQSNTDWGVLMLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIG
HHHCCHHHHHHHHCCCCCEEEEEECCCCEEHHHHHCCCCCHHHHHCEEEEECCCHHHHHH
LLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIGLALIIGIGASCAFMLPVATP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCC
PNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]