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The map label for this gene is rpoB [H]

Identifier: 148825209

GI number: 148825209

Start: 78222

End: 82253

Strand: Direct

Name: rpoB [H]

Synonym: CGSHiEE_00425

Alternate gene names: 148825209

Gene position: 78222-82253 (Clockwise)

Preceding gene: 148825208

Following gene: 148825210

Centisome position: 4.31

GC content: 39.34

Gene sequence:

>4032_bases
ATGGGTTACTCCTATTCTGAAAAAAAACGAATTCGTAAAGATTTCGGTAAACGTCCGCAAGTTTTAAATGTTCCTTATTT
ATTAACCATTCAGTTGGATTCTTTTGATAAATTTATTCAAAAAGATCCTGAAGGTCAGCAAGGTTTAGAAGCGGCATTCC
GTTCTGTATTCCCTATTGTAAGCAATAATGGCTATACAGAATTACAATATGTAGATTATCGTTTAGAAGAGCCAGAGTTT
GATGTACGTGAGTGCCAAATTCGTGGCTCAACTTATGCAGCAGGCTTACGTGTAAAATTACGTTTAGTGAGCTACGATAA
AGAATCTTCTTCACGCGCAGTTAAAGATATTAAAGAAAATGAAGTTTATATGGGGGAAATCCCATTAATGACTGATAACG
GTACTTTTGTAATTAATGGTACCGAGCGTGTTATCGTTTCACAATTACACCGTAGTCCAGGTGTATTCTTTGATTCTGAC
AAAGGTAAAACCCATTCTTCAGGTAAAGTGCTTTATAACGCACGCATCATTCCTTATCGTGGTTCTTGGTTAGATTTTGA
ATTCGATCCAAAAGATAACTTATTTGCGCGTATTGACCGTCGCCGTAAATTACCGGCAACAATCATTCTTCGTGCATTAG
GCTACACCACTGAAGAAATCTTAAACTTATTCTTTGATAAAATTACCTTTGAAATCTCTGGCGATAAATTGTTAATGACT
TTAGTGCCAGAACGTTTACGTGGTGAAACGGCTTCTTTTGATATTGAAGCAAATGGCAAAGTGTATGTTGAACGTGGTCG
TCGCATCACTGCTCGTCACATTAAAGCATTAGAAAAAGATAATATCTCACAAGTGGTTGTGCCTTCTGAATATATTTTAG
GTAAAGTTGCGTCGAAAGATTATGTTGATTTAGAGTCTGGCGAAATTATTTGTCCTGCAAATGGTGAGATTTCTTTAGAG
ACTCTTGCAAAATTAGCACAAGCTGGTTACACCACGATCGAAACTTTATTTACTAATGATTTAGATTACGGTCCATATAT
TTCTGAAACGCTACGTGTCGATCCAACTTATGACAAAACCAGTGCGCTTTACGAAATTTATCGTATGATGCGTCCGGGCG
AGCCACCAACACCAGAATCTTCAGAAGCGTTATTCAATAATTTATTCTTCTCTGCAGAACGTTATGATTTATCTACAGTA
GGTCGTATGAAGTTCAACCGTTCTTTAGCTTTTCCAGAAGGGGAAGGTGCGGGTATTTTAAGCAATGAAGATATTATTGC
GGTAATGCGTAAATTGATCGACATCCGTAATGGTCGTGGCGAAGTAGACGATATTGACCATTTGGGTAACCGTCGTATCC
GTAGCGTGGGCGAAATGGCTGAAAACCAATTCCGTATCGGTTTAGTGCGTGTTGAAAGAGCGGTGAAAGAACGCTTATCT
TTAGGTGATTTAGATGCAATCACACCGCAAGACTTAATTAACCCGAAACCGATTTCTGCGGCAGTAAAAGAATTCTTTGG
TTCTTCACAGCTTTCGCAATTTATGGATCAAAACAACCCATTGTCAGAAGTGACACACAAACGTCGTATTTCTGCATTAG
GTCCGGGCGGTTTAACGCGTGAGCGTGCAGGCTTTGAAGTGCGTGACGTACATAATACTCACTATGGTCGTTTATGTCCG
ATTGAAACCCCTGAAGGTCCAAACATCGGTTTGATCAACTCACTTTCTGCTTTTGCACGTACTAATGATTATGGTTTCTT
AGAAACACCATATCGTAAAGTGGTTGATGGTCAAGTTACTGAAGAAATTGAATACTTATCTGCAATTGATGAAGCAAACT
ACATCATTGCACAGGCAAACTCAAACTTAGACGAAAATAACCGTTTTACTGATGCTTTCGTTACTGCTCGTGGTGAACGT
GGTGAATCTGGTTTATATAAACCCGAAGATATTCACTATATGGATGTTTCGACACAACAAGTGGTATCTGTTGCGGCTGC
ATTAATTCCATTCCTTGAGCATGACGATGCGAACCGTGCGTTGATGGGTGCGAACATGCAACGTCAAGCAGTTCCAACAT
TACGTGCTGACAAACCATTAGTTGGTACAGGTATGGAAAAACCAATTGCACTTGACTCAGGTGTTGCGGTTGTTGCAAAA
CGTGGAGGTACAGTTCAGTACGTCGATGCGTCTCGTATTGTTATTAAAGTAAATGAAGATGAAACCATTGCAGGTGAAGC
TGGTATTGATATTTATAACTTAATCAAATATACCCGTTCTAACCAAAATACTTGTATTAACCAAATTCCTTGTGTGAATT
TAGGCGATCCAATTAATCGTGGTGAAGTATTAGCAGACGGTCCTTCAACTGATTTAGGGGAACTTGCATTAGGTCAAAAT
ATTCGCGTAGCGTTCATGCCTTGGAACGGCTATAACTTTGAAGACTCAATGTTAGTTTCTGAACGTGTTGTTCAACAAGA
CCGTTTTACTACAATTCACATTCAAGAGTTATCTTGTGTTGCGCGTGATACTAAATTAGGTTCAGAAGAAATTACGGCAG
ATATTCCAAATGTAGGGGAGTCTGCATTAAGTAAACTTGATGAATCTGGTATCGTTTATGTCGGCGCTGAAGTTAAAGGT
GGCGACATCTTAGTAGGTAAAGTAACCCCTAAAGGCGAAACTCAATTAACCCCAGAAGAAAAATTGTTACGTGCAATCTT
TGGGGAAAAAGCTTCCGATGTGAAAGATTCTTCATTACGCGTGCCAAATGGTACATCAGGTACGGTTATTGATGTTCAAG
TCTTCACTCGTGACGGCGTAGAAAAAGATAAACGTGCATTAGAAATCGAAGAAATGCAACTTCGTGAAGCGAAAAAAGAT
TTAACTGAAGAGTTAGAGATTTTAGAAGCTGGTTTATTTGCTCGTGTGCGTAATCTTCTTATTTCTAGTGGTGCTGATGC
AGCGCAATTAGATAAATTAGATCGCACTAAATGGTTAGAACAAACCATTGCAGATGAAGAAAAACAAAACCAATTAGAAC
AGCTTGCTGAGCAATACGAAGAACTTCGTAAAGAGTTTGAACATAAACTTGAAGTGAAACGTAAGAAAATCATTAAAGGC
GATGATCTTGCACCGGGCGTATTAAAAGTTGTGAAAGTTTACCTTGCAGTGAAACGTCAAATCCAGCCGGGAGATAAAAT
GGCGGGTCGTCACGGTAACAAAGGTGTTATCTCGAAAATTAACCCAGTTGAAGATATGCCATACGATGAAAATGGTCAGC
CAGTTGAAATCGTATTAAACCCACTGGGCGTACCGTCTCGTATGAACATCGGTCAGATCCTTGAAACTCACTTAGGTTTA
GCGGCAAAAGGTATTGGTGATCAAATCAATACAATGCTTAAACAAAAACAAGAAGTGGAAAAATTACGTAGCTATATCCA
AAAAGCATACGATTTATTAGGTAATGGTTCACAAAAAGTGGATTTAAGCACTTTTACTGATGAAGAAGTATTGCGTTTAG
CGGGAAATTTACGTAAAGGCTTACCAGTTGCAACGCCAGTGTTCGATGGTGCAGACGAAGCGGAAATCAAAGAACTATTA
AAACTTGGTGGATTACCAACTTCAGGTCAAATTACCCTTTACGATGGTCGTACTGGCGAGAAATTTGAACGTCCAGTAAC
CGTAGGTTATATGTACATGCTCAAATTGAACCACTTAGTTGATGATAAAATGCACGCTCGTTCAACAGGTTCTTATAGCC
TTGTTACACAACAGCCATTGGGTGGTAAAGCACAATTTGGTGGTCAGCGTTTCGGTGAGATGGAGGTATGGGCACTTGAA
GCATATGGTGCAGCCTACACCTTACAAGAAATGCTAACTGTGAAATCCGATGATGTGAATGGTCGTACGAAGATGTATAA
AAATATCGTAAGTGGCAATCAACATATGGACCCAGGCACACCGGAATCTTTCAACGTAATTATGAAAGAAATCCGCTCAC
TTGGTTTAAATATCGAGTTAGACGAAGAGTAA

Upstream 100 bases:

>100_bases
CCACTATAGAAGTAAGGTTCAGAGTGCGGTCATTTTAACGGTCATTCACGTCACAGTTAGTTTGTGGCTAGGTCACTGAA
CAGTTAGCAGAGGAAAACCA

Downstream 100 bases:

>100_bases
TTTCATTCTTGCCTTCCCCCGTAAACAGGGGGAGCGAAGAGAAAGAATGACGAAACAATAAATCGCCGAAGTGCGGTCAA
AATTCTCCGAAATTTTTAAC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1343; Mature: 1342

Protein sequence:

>1343_residues
MGYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEF
DVRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEISGDKLLMT
LVPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLE
TLAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKTSALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTV
GRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLS
LGDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCP
IETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSAIDEANYIIAQANSNLDENNRFTDAFVTARGER
GESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAK
RGGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQN
IRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGSEEITADIPNVGESALSKLDESGIVYVGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKD
LTEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKG
DDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGL
AAKGIGDQINTMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELL
KLGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGTPESFNVIMKEIRSLGLNIELDEE

Sequences:

>Translated_1343_residues
MGYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEF
DVRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEISGDKLLMT
LVPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLE
TLAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKTSALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTV
GRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLS
LGDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCP
IETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSAIDEANYIIAQANSNLDENNRFTDAFVTARGER
GESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAK
RGGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQN
IRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGSEEITADIPNVGESALSKLDESGIVYVGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKD
LTEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKG
DDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGL
AAKGIGDQINTMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELL
KLGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGTPESFNVIMKEIRSLGLNIELDEE
>Mature_1342_residues
GYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFD
VRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDK
GKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEISGDKLLMTL
VPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLET
LAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKTSALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVG
RMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSL
GDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPI
ETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSAIDEANYIIAQANSNLDENNRFTDAFVTARGERG
ESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKR
GGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNI
RVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGSEEITADIPNVGESALSKLDESGIVYVGAEVKGG
DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDL
TEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGD
DLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLA
AKGIGDQINTMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLK
LGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA
YGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGTPESFNVIMKEIRSLGLNIELDEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=263, Percent_Identity=31.1787072243346, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI212286172, Length=263, Percent_Identity=31.1787072243346, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI238908505, Length=297, Percent_Identity=28.6195286195286, Blast_Score=111, Evalue=6e-24,
Organism=Homo sapiens, GI238908503, Length=297, Percent_Identity=28.6195286195286, Blast_Score=111, Evalue=6e-24,
Organism=Homo sapiens, GI4505941, Length=249, Percent_Identity=31.3253012048193, Blast_Score=109, Evalue=2e-23,
Organism=Escherichia coli, GI1790419, Length=1343, Percent_Identity=83.0975428145942, Blast_Score=2318, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506623, Length=234, Percent_Identity=32.0512820512821, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17552304, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=302, Percent_Identity=27.8145695364238, Blast_Score=100, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324781, Length=248, Percent_Identity=32.6612903225806, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324725, Length=250, Percent_Identity=33.2, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=253, Percent_Identity=31.2252964426877, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136446, Length=262, Percent_Identity=32.4427480916031, Blast_Score=113, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17647877, Length=248, Percent_Identity=31.8548387096774, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=105, Evalue=2e-22,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 149806; Mature: 149675

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIV
CCCCHHHHHHHHHHHCCCCCEEECCEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCCC
SNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKEN
CCCCEEEEEEEEEECCCCCCCCHHEEECCCEEEECEEEEEEEEECCCCCHHHHHHHHHCC
EVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
CEEEECEEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEISGDKLLMT
CCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEECCCEEEEE
LVPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKD
ECCHHHCCCCCEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCHHHHHHHHCCCC
YVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKT
CEECCCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHEECCCCCCHH
SALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGIL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLS
CCCHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHCC
LGDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTR
CCCCCCCCHHHCCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVT
HHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHH
EEIEYLSAIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCHHH
VVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAK
HHHHHHHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEE
RGGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINR
CCCEEEEEECCEEEEEECCCCEECCCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCC
GEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCV
CCEEECCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKD
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LTEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
NPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINTMLKQKQEVE
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHH
KLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELL
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
KLGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHCCCCCCCEEEEEECCCCCHHCCCEEHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGT
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVIMKEIRSLGLNIELDEE
CHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
GYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIV
CCCHHHHHHHHHHHCCCCCEEECCEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCCC
SNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKEN
CCCCEEEEEEEEEECCCCCCCCHHEEECCCEEEECEEEEEEEEECCCCCHHHHHHHHHCC
EVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
CEEEECEEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEISGDKLLMT
CCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEECCCEEEEE
LVPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKD
ECCHHHCCCCCEEEEECCCEEEEECCCEEHHHHHHHHHHCCCCEEECCHHHHHHHHCCCC
YVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKT
CEECCCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHEECCCCCCHH
SALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGIL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLS
CCCHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHCC
LGDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTR
CCCCCCCCHHHCCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVT
HHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHH
EEIEYLSAIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCHHH
VVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAK
HHHHHHHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCCEEEEE
RGGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINR
CCCEEEEEECCEEEEEECCCCEECCCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCC
GEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCV
CCEEECCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKD
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LTEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
NPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINTMLKQKQEVE
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHH
KLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELL
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
KLGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHCCCCCCCEEEEEECCCCCHHCCCEEHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMDPGT
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVIMKEIRSLGLNIELDEE
CHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA