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The map label for this gene is espB [H]

Identifier: 148825089

GI number: 148825089

Start: 4373543

End: 4374925

Strand: Reverse

Name: espB [H]

Synonym: TBFG_13916

Alternate gene names: 148825089

Gene position: 4374925-4373543 (Counterclockwise)

Preceding gene: 148825090

Following gene: 148825088

Centisome position: 98.88

GC content: 65.15

Gene sequence:

>1383_bases
ATGACGCAGTCGCAGACCGTGACGGTGGATCAGCAAGAGATTTTGAACAGGGCCAACGAGGTGGAGGCCCCGATGGCGGA
CCCACCGACTGATGTCCCCATCACACCGTGCGAACTCACGGCGGCTAAAAACGCCGCCCAACAGCTGGTATTGTCCGCCG
ACAACATGCGGGAATACCTGGCGGCCGGTGCCAAAGAGCGGCAGCGTCTGGCGACCTCGCTGCGCAACGCGGCCAAGGCG
TATGGCGAGGTTGATGAGGAGGCTGCGACCGCGCTGGACAACGACGGCGAAGGAACTGTGCAGGCAGAATCGGCCGGGGC
CGTCGGAGGGGACAGTTCGGCCGAACTAACCGATACGCCGAGGGTGGCCACGGCCGGTGAACCCAACTTCATGGATCTCA
AAGAAGCGGCAAGGAAGCTCGAAACGGGCGACCAAGGCGCATCGCTCGCGCACTTTGCGGATGGGTGGAACACTTTCAAC
CTGACGCTGCAAGGCGACGTCAAGCGGTTCCGGGGGTTTGACAACTGGGAAGGCGATGCGGCTACCGCTTGCGAGGCTTC
GCTCGATCAACAACGGCAATGGATACTCCACATGGCCAAATTGAGCGCTGCGATGGCCAAGCAGGCTCAATATGTCGCGC
AGCTGCACGTGTGGGCTAGGCGGGAACATCCGACTTATGAAGACATAGTCGGGCTCGAACGGCTTTACGCGGAAAACCCT
TCGGCCCGCGACCAAATTCTCCCGGTGTACGCGGAGTATCAGCCGAGGTCGGAGAAGGTGCTGACCGAATACAACAACAA
GGCAGCCCTGGAACCGGTAAACCCGCCGAAGCCTCCCCCCGCCATCAAGATCGACCCGCCCCCGCCTCCGCAAGAGCAGG
GATTGATCCCTGGCTTCCTGATGCCGCCGTCTGACGGCTCCGGTGTGACTCCCGGTACCGGGATGCCAGCCGCACCGATG
GTTCCGCCTACCGGATCGCCGGGTGGTGGCCTCCCGGCTGACACGGCGGCGCAGCTGACGTCGGCTGGGCGGGAAGCCGC
AGCGCTGTCGGGCGACGTGGCGGTCAAAGCGGCATCGCTCGGTGGCGGTGGAGGCGGCGGGGTGCCGTCGGCGCCGTTGG
GATCCGCGATCGGGGGCGCCGAATCGGTGCGGCCCGCTGGCGCTGGTGACATTGCCGGCTTAGGCCAGGGAAGGGCCGGC
GGCGGCGCCGCGCTGGGCGGCGGTGGCATGGGAATGCCGATGGGTGCCGCGCATCAGGGACAAGGGGGCGCCAAGTCCAA
GGGTTCTCAGCAGGAAGACGAGGCGCTCTACACCGAGGATCGGGCATGGACCGAGGCCGTCATTGGTAACCGTCGGCGCC
AGGACAGTAAGGAGTCGAAGTGA

Upstream 100 bases:

>100_bases
CCGTTCGCGATGCCGGCATGAACGGGCGGCATCAAATTAGTGCAGGAACCTTTCAGTTTAGCGACGATAATGGCTATAGC
ACTAAGGAGGATGATCCGAT

Downstream 100 bases:

>100_bases
GCATGGACGAATTGGACCCGCATGTCGCCCGGGCGTTGACGCTGGCGGCGCGGTTTCAGTCGGCCCTAGACGGGACGCTC
AATCAGATGAACAACGGATC

Product: hypothetical protein

Products: NA

Alternate protein names: Antigen MTB48 [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKA
YGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFN
LTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENP
SARDQILPVYAEYQPRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPM
VPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAG
GGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK

Sequences:

>Translated_460_residues
MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKA
YGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFN
LTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENP
SARDQILPVYAEYQPRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPM
VPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAG
GGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
>Mature_459_residues
TQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAY
GEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNL
TLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPS
ARDQILPVYAEYQPRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMV
PPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGG
GAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS). Secretion requires both EspK and EccCb1 [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47563; Mature: 47432

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYL
CCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTP
HCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC
RVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDA
CEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEEECCHHHHCCCCCCCCCH
ATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
SARDQILPVYAEYQPRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFL
CCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
MPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASL
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCEEEEEECC
GGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQG
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
QGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYL
CCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTP
HCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC
RVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDA
CEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEEECCHHHHCCCCCCCCCH
ATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
SARDQILPVYAEYQPRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFL
CCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
MPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASL
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCEEEEEECC
GGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQG
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
QGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427558; 9634230; 12218036 [H]