Click here to switch to the map view.

The map label for this gene is espK

Identifier: 148825087

GI number: 148825087

Start: 4370593

End: 4372782

Strand: Reverse

Name: espK

Synonym: TBFG_13914

Alternate gene names: 148825087

Gene position: 4372782-4370593 (Counterclockwise)

Preceding gene: 148825088

Following gene: 148825070

Centisome position: 98.83

GC content: 67.49

Gene sequence:

>2190_bases
ATGAGTATTACCAGGCCGACGGGCAGCTATGCCAGACAGATGCTGGATCCGGGCGGCTGGGTGGAAGCCGATGAAGACAC
TTTCTATGACCGGGCCCAGGAATATAGCCAGGTTTTGCAAAGGGTCACCGATGTATTGGACACCTGCCGCCAGCAGAAAG
GCCACGTCTTCGAAGGCGGCCTATGGTCCGGCGGCGCCGCCAATGCTGCCAACGGCGCCCTGGGTGCAAACATCAATCAA
TTGATGACGCTGCAGGATTATCTCGCCACGGTGATTACCTGGCACAGGCATATTGCCGGGTTGATTGAGCAAGCTAAATC
CGATATCGGCAATAATGTGGATGGCGCTCAACGGGAGATCGATATCCTGGAGAATGACCCTAGCCTGGATGCTGATGAGC
GCCATACCGCCATCAATTCATTGGTCACGGCGACGCATGGGGCCAATGTCAGTCTGGTCGCCGAGACCGCTGAGCGGGTG
CTGGAATCCAAGAATTGGAAACCTCCGAAGAACGCACTCGAGGATTTGCTTCAGCAGAAGTCGCCGCCACCCCCAGACGT
GCCTACCCTGGTCGTGCCATCCCCGGGCACACCGGGCACACCGGGAACCCCGATCACCCCGGGAACCCCGATCACCCCGG
GAACCCCAATCACACCCATCCCGGGAGCGCCGGTAACTCCGATCACACCAACGCCCGGCACTCCCGTCACGCCGGTGACC
CCGGGCAAGCCGGTCACCCCGGTGACCCCGGTCAAACCGGGCACACCAGGCGAGCCAACCCCGATCACGCCGGTCACCCC
CCCGGTCGCCCCGGCCACACCGGCAACCCCGGCCACGCCCGTTACCCCAGCTCCCGCTCCACACCCGCAGCCGGCTCCGG
CACCGGCGCCATCGCCTGGGCCCCAGCCGGTTACACCGGCCACTCCCGGTCCGTCTGGTCCAGCAACACCGGGCACCCCA
GGGGGCGAGCCGGCGCCGCACGTCAAACCCGCGGCGTTGGCGGAGCAACCTGGTGTGCCGGGCCAGCATGCGGGCGGGGG
GACGCAGTCGGGGCCTGCCCATGCGGACGAATCCGCCGCGTCGGTGACGCCGGCTGCGGCGTCCGGTGTCCCGGGCGCAC
GGGCGGCGGCCGCCGCGCCGAGCGGTACCGCCGTGGGAGCGGGCGCGCGTTCGAGCGTGGGTACGGCCGCGGCCTCGGGC
GCGGGGTCGCATGCTGCCACTGGGCGGGCGCCGGTGGCTACCTCGGACAAGGCGGCGGCACCGAGCACGCGGGCGGCCTC
GGCGCGGACGGCACCTCCTGCCCGCCCGCCGTCGACCGATCACATCGACAAACCCGATCGCAGCGAGTCTGCAGATGACG
GTACGCCGGTGTCGATGATCCCGGTGTCGGCGGCTCGGGCGGCACGCGACGCCGCCACTGCAGCTGCCAGCGCCCGCCAG
CGTGGCCGCGGTGATGCGCTGCGGTTGGCGCGACGCATCGCGGCGGCGCTCAACGCGTCCGACAACAACGCGGGCGACTA
CGGGTTCTTCTGGATCACCGCGGTGACCACCGACGGTTCCATCGTCGTGGCCAACAGCTATGGGCTGGCCTACATACCCG
ACGGGATGGAATTGCCGAATAAGGTGTACTTGGCCAGCGCGGATCACGCAATCCCGGTTGACGAAATTGCACGCTGTGCC
ACCTACCCGGTTTTGGCCGTGCAAGCCTGGGCGGCTTTCCACGACATGACGCTGCGGGCGGTGATCGGTACCGCGGAGCA
GTTGGCCAGTTCGGATCCCGGTGTGGCCAAGATTGTGCTGGAGCCAGATGACATTCCGGAGAGCGGCAAAATGACGGGCC
GGTCGCGGCTGGAGGTCGTCGACCCCTCGGCGGCGGCTCAGCTGGCCGACACTACCGATCAGCGTTTGCTCGACTTGTTG
CCGCCGGCGCCGGTGGATGTCAATCCACCGGGCGATGAGCGGCACATGCTGTGGTTCGAGCTGATGAAGCCCATGACCAG
CACCGCTACCGGCCGCGAGGCCGCTCATCTGCGGGCGTTCCGGGCCTACGCTGCCCACTCACAGGAGATTGCCCTGCACC
AAGCGCACACTGCGACTGACGCGGCCGTCCAGCGTGTGGCCGTCGCGGACTGGCTGTACTGGCAATACGTCACCGGGTTG
CTCGACCGGGCCCTGGCCGCCGCATGCTGA

Upstream 100 bases:

>100_bases
GCGCGGGGTGGATCCAGCGGCCGAGCCGGCGTGAAATGCCGGAGGCCAACCGGACGGTGATCCGCGAGGCGATCTGGCGG
TTTGGGGAGGGCAGTAGGGG

Downstream 100 bases:

>100_bases
CGAGGCCAGGACAGCAACAGGCGCTGCGTGCGAGACGGAGCCGCTGGCAGGCCCGGTCTACAACGTTGTGGTTGTTGAGG
GTGCCGGAGTCGACGGATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGGLWSGGAANAANGALGANINQ
LMTLQDYLATVITWHRHIAGLIEQAKSDIGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETAERV
LESKNWKPPKNALEDLLQQKSPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITPTPGTPVTPVT
PGKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAPAPSPGPQPVTPATPGPSGPATPGTP
GGEPAPHVKPAALAEQPGVPGQHAGGGTQSGPAHADESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASG
AGSHAATGRAPVATSDKAAAPSTRAASARTAPPARPPSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQ
RGRGDALRLARRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPNKVYLASADHAIPVDEIARCA
TYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL
PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEIALHQAHTATDAAVQRVAVADWLYWQYVTGL
LDRALAAAC

Sequences:

>Translated_729_residues
MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGGLWSGGAANAANGALGANINQ
LMTLQDYLATVITWHRHIAGLIEQAKSDIGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETAERV
LESKNWKPPKNALEDLLQQKSPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITPTPGTPVTPVT
PGKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAPAPSPGPQPVTPATPGPSGPATPGTP
GGEPAPHVKPAALAEQPGVPGQHAGGGTQSGPAHADESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASG
AGSHAATGRAPVATSDKAAAPSTRAASARTAPPARPPSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQ
RGRGDALRLARRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPNKVYLASADHAIPVDEIARCA
TYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL
PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEIALHQAHTATDAAVQRVAVADWLYWQYVTGL
LDRALAAAC
>Mature_728_residues
SITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGGLWSGGAANAANGALGANINQL
MTLQDYLATVITWHRHIAGLIEQAKSDIGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETAERVL
ESKNWKPPKNALEDLLQQKSPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITPTPGTPVTPVTP
GKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAPAPSPGPQPVTPATPGPSGPATPGTPG
GEPAPHVKPAALAEQPGVPGQHAGGGTQSGPAHADESAASVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASGA
GSHAATGRAPVATSDKAAAPSTRAASARTAPPARPPSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQR
GRGDALRLARRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPNKVYLASADHAIPVDEIARCAT
YPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLLP
PAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEIALHQAHTATDAAVQRVAVADWLYWQYVTGLL
DRALAAAC

Specific function: May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESPK_MYCTU (O69743)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   E70803
- RefSeq:   NP_218396.1
- RefSeq:   NP_338547.1
- EnsemblBacteria:   EBMYCT00000002015
- EnsemblBacteria:   EBMYCT00000072999
- GeneID:   886212
- GeneID:   926283
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3993
- KEGG:   mtu:Rv3879c
- TIGR:   MT3993
- TubercuList:   Rv3879c
- GeneTree:   EBGT00050000014850
- HOGENOM:   HBG569623
- OMA:   TEEQFAN
- ProtClustDB:   CLSK792781
- GO:   GO:0005829

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 74493; Mature: 74361

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGG
CCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
LWSGGAANAANGALGANINQLMTLQDYLATVITWHRHIAGLIEQAKSDIGNNVDGAQREI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHE
DILENDPSLDADERHTAINSLVTATHGANVSLVAETAERVLESKNWKPPKNALEDLLQQK
EEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHC
SPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITPTPGTPVTPVT
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAPAPSPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQPVTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSGPAHADESAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
SVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASGAGSHAATGRAPVATSDKAAA
HCCCHHHCCCCCCHHHHCCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCC
PSTRAASARTAPPARPPSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
RGRGDALRLARRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPN
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEECCCCCCCCC
KVYLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVL
EEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
EPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLLPPAPVDVNPPGDERHMLWFE
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LMKPMTSTATGREAAHLRAFRAYAAHSQEIALHQAHTATDAAVQRVAVADWLYWQYVTGL
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRALAAAC
HHHHHHHCC
>Mature Secondary Structure 
SITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGG
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
LWSGGAANAANGALGANINQLMTLQDYLATVITWHRHIAGLIEQAKSDIGNNVDGAQREI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHE
DILENDPSLDADERHTAINSLVTATHGANVSLVAETAERVLESKNWKPPKNALEDLLQQK
EEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHC
SPPPPDVPTLVVPSPGTPGTPGTPITPGTPITPGTPITPIPGAPVTPITPTPGTPVTPVT
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGKPVTPVTPVKPGTPGEPTPITPVTPPVAPATPATPATPVTPAPAPHPQPAPAPAPSPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PQPVTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGVPGQHAGGGTQSGPAHADESAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
SVTPAAASGVPGARAAAAAPSGTAVGAGARSSVGTAAASGAGSHAATGRAPVATSDKAAA
HCCCHHHCCCCCCHHHHCCCCCCEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCC
PSTRAASARTAPPARPPSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAASARQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
RGRGDALRLARRIAAALNASDNNAGDYGFFWITAVTTDGSIVVANSYGLAYIPDGMELPN
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCEEEECCCCEEECCCCCCCCC
KVYLASADHAIPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVL
EEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
EPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLLPPAPVDVNPPGDERHMLWFE
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LMKPMTSTATGREAAHLRAFRAYAAHSQEIALHQAHTATDAAVQRVAVADWLYWQYVTGL
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRALAAAC
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036