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The map label for this gene is 148824996

Identifier: 148824996

GI number: 148824996

Start: 4248375

End: 4248740

Strand: Direct

Name: 148824996

Synonym: TBFG_13823

Alternate gene names: NA

Gene position: 4248375-4248740 (Clockwise)

Preceding gene: 148824995

Following gene: 148824997

Centisome position: 96.02

GC content: 62.57

Gene sequence:

>366_bases
ATGCGGTTCGTTGTCACCGGCGGCCTCGCTGGGATAGTTGACTTTGGCCTCTACGTCGTGCTGTACAAGGTGGCGGGCCT
ACAGGTCGACCTGTCCAAGGCCATCAGCTTCATCGTCGGCACCATCACCGCGTACCTGATCAACCGCCGGTGGACATTCC
AGGCCGAGCCCAGCACGGCCCGATTCGTCGCGGTCATGCTCCTCTACGGAATCACCTTCGCCGTGCAGGTCGGACTCAAC
CACCTCTGCCTCGCACTCTTGCACTACCGGGCGTGGGCCATCCCCGTCGCGTTTGTGATCGCGCAGGGCACCGCCACGGT
AATCAACTTCATCGTGCAGCGAGCCGTGATCTTCCGGATCCGCTGA

Upstream 100 bases:

>100_bases
CCGCACCAGGCTCGCCGCCCCCATTAGACTTCCCCCGATGATCCGATCGGAGTCTGGTGCCGCGCCGCCACGCCAACACC
TGCACCTGTCGGCACAGGTA

Downstream 100 bases:

>100_bases
GCCGGTCAGGGTCGAATCGGGCGGGTACCCTCTTTGACGATGTTGAGCGTGGGAGCTACCACTACCGCCACCCGGCTGAC
CGGGTGGGGCCGCACAGCGC

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLN
HLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR

Sequences:

>Translated_121_residues
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLN
HLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR
>Mature_121_residues
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLN
HLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR

Specific function: Unknown

COG id: COG2246

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gtrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3789_MYCTU (P64292)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   A70697
- RefSeq:   NP_218306.1
- RefSeq:   NP_338448.1
- EnsemblBacteria:   EBMYCT00000002016
- EnsemblBacteria:   EBMYCT00000070050
- GeneID:   886109
- GeneID:   922609
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3897
- KEGG:   mtu:Rv3789
- TIGR:   MT3897
- TubercuList:   Rv3789
- GeneTree:   EBGT00050000016022
- HOGENOM:   HBG428785
- OMA:   AVQVGIN
- ProtClustDB:   CLSK2484248
- GO:   GO:0006810
- InterPro:   IPR007267

Pfam domain/function: PF04138 GtrA

EC number: NA

Molecular weight: Translated: 13377; Mature: 13377

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d87da24)-; HASH(0x1e5bc248)-; HASH(0x1e17cb3c)-; HASH(0x1e997bb8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTA
CEEEEECCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
RFVAVMLLYGITFAVQVGLNHLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
R
H
>Mature Secondary Structure
MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTA
CEEEEECCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
RFVAVMLLYGITFAVQVGLNHLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
R
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036