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The map label for this gene is sigD

Identifier: 148824621

GI number: 148824621

Start: 3844330

End: 3844968

Strand: Reverse

Name: sigD

Synonym: TBFG_13448

Alternate gene names: 148824621

Gene position: 3844968-3844330 (Counterclockwise)

Preceding gene: 148824622

Following gene: 148824620

Centisome position: 86.9

GC content: 65.73

Gene sequence:

>639_bases
ATGGTCGATCCGGGAGTTAGCCCGGGATGTGTCCGCTTCGTAACGTTGGAGATATCGCCGTCGATGACAATGCAAGGGGA
ACGTCTCGACGCTGTGGTTGCGGAGGCCGTGGCAGGAGACCGGAACGCGCTTCGGGAGGTGCTGGAGACCATCCGCCCGA
TCGTCGTGCGATATTGCCGAGCGCGAGTCGGCACGGTCGAGCGGAGCGGCCTGTCAGCAGATGACGTGGCACAGGAGGTG
TGCTTGGCCACCATAACGGCGCTGCCGCGCTATCGGGACCGCGGCCGGCCATTCCTGGCGTTTCTGTACGGCATCGCGGC
GCACAAGGTTGCCGACGCCCATCGGGCAGCCGGCCGTGACCGGGCCTATCCCGCCGAAACGCTTCCTGAGCGCTGGTCAG
CCGACGCCGGCCCGGAGCAGATGGCCATCGAGGCCGATTCGGTCACCCGGATGAACGAATTGCTTGAGATCTTGCCGGCC
AAGCAACGCGAGATCCTCATTCTGCGTGTTGTCGTCGGCCTGTCCGCGGAAGAGACCGCCGCCGCCGTCGGCAGCACCAC
GGGGGCGGTCCGGGTGGCCCAACACCGTGCACTTCAGCGGCTGAAGGACGAGATTGTTGCGGCAGGTGACTATGCGTGA

Upstream 100 bases:

>100_bases
AACAGCTGCGCGAACTCACCAAAATACGCAATATTTGCGCAGGCCAGGTGCGGCGCGCCGGTGGATGCTGGCGTACCGCT
TAAAACGCGGTTGGGCCGTT

Downstream 100 bases:

>100_bases
ATTTGGTAATCCCCTTGGCGATCGGCCGCCATTGGATGAGCTGGCCCGCACCGATCTGCTGCTCGACGCACTCGCCGAAC
GGGAGGAGGTTGACTTCGCG

Product: RNA polymerase sigma factor SigD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEV
CLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPA
KQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA

Sequences:

>Translated_212_residues
MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEV
CLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPA
KQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
>Mature_212_residues
MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEV
CLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPA
KQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPSD_MYCBO (P66812)

Other databases:

- EMBL:   BX248346
- RefSeq:   NP_857088.1
- ProteinModelPortal:   P66812
- SMR:   P66812
- EnsemblBacteria:   EBMYCT00000017616
- GeneID:   1091026
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3448c
- GeneTree:   EBGT00050000015256
- HOGENOM:   HBG753452
- OMA:   ICLAVAT
- ProtClustDB:   PRK09648
- BioCyc:   MBOV233413:MB3448C-MONOMER
- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02937

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2; SSF88946 Sigma_r2; SSF88659 Sigma_r3_r4

EC number: NA

Molecular weight: Translated: 22920; Mature: 22920

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCR
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRD
HHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
RAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETA
CCCCHHHHHHHCCCCCCCHHEEECHHHHHHHHHHHHHCCCCCHHEEHHHHHHCCCCHHHH
AAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCR
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRD
HHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
RAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETA
CCCCHHHHHHHCCCCCCCHHEEECHHHHHHHHHHHHHCCCCCHHEEHHHHHHCCCCHHHH
AAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972