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The map label for this gene is crtB

Identifier: 148824605

GI number: 148824605

Start: 3825207

End: 3826115

Strand: Reverse

Name: crtB

Synonym: TBFG_13432

Alternate gene names: 148824605

Gene position: 3826115-3825207 (Counterclockwise)

Preceding gene: 148824606

Following gene: 148824604

Centisome position: 86.48

GC content: 62.82

Gene sequence:

>909_bases
ATGACCGAGATCGAACAGGCGTATCGAATCACCGAGTCGATCACGCGCACGGCCGCCAGAAACTTCTACTACGGCATCCG
ACTCTTGCCGCGCGAAAAGCGAGCGGCACTATCTGCGGTCTATGCGCTCGGCCGCCGGATCGACGACGTCGCCGACGGCG
AGCTGGCCCCCGAGACCAAGATCACCGAGCTCGATGCCATCAGGAAATCACTTGATAATATTGATGATTCATCCGATCCG
GTGCTGGTTGCGCTGGCTGACGCGGCTCGCCGGTTTCCGGTGCCGATCGCGATGTTCGCAGAGTTGATTGACGGCGCCCG
TATGGAAATCGACTGGACTGGTTGCCGCGATTTCGACGAGCTGATCGTCTACTGCCGCCGGGGGGCCGGCACGATCGGAA
AGCTTTGTCTTTCCATCTTTGGACCCGTCAGCACGGCGACGTCGCGATACGCCGAGCAGTTGGGAATCGCTCTGCAGCAA
ACCAATATTCTGCGCGACGTTCGAGAGGACTTTTTGAATGGACGGATCTACCTGCCGCGCGACGAGCTGGACCGATTAGG
CGTACGCCTCCGCCTGGACGACACCGGGGCACTCGATGACCCCGACGGACGGCTCGCGGCACTGCTGCGGTTCAGTGCCG
ACCGCGCCGCAGACTGGTATTCGCTGGGACTGCGGCTGATTCCACACCTCGACCGCCGCAGCGCTGCCTGCTGTGCGGCC
ATGTCTGGCATCTACCGCCGTCAGCTCGCCTTGATCAGAGCATCGCCGGCGGTCGTCTACGATCGGCGAATCTCTCTGTC
GGGACTGAAGAAGGCCCAAGTGGCGGCGGCAGCACTGGCCTCTTCGGTAACCTGCGGACCGGCCCATGGACCGCTACCGG
CCGACCTCGGGAGTCACCCCAGCCACTAG

Upstream 100 bases:

>100_bases
ATCGGCATTCCCGATCGCCCGGCCGCTGAGCTTCAGGATTTGGCTCACTACATCGTCGATCGTCAGGCGTGACTGACCAA
CACCGTAGTTGGAGGACGGC

Downstream 100 bases:

>100_bases
ACTGACTGGCCGTGGTGCAGCCTGCTGACATCGACGTGCCTGAGACACCGGCTCGACCGGTGTTGGTGGTCGACTTCGGT
GCCCAATATGCCCAGTTGAT

Product: phytoene synthase phyA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDP
VLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQ
TNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAA
MSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH

Sequences:

>Translated_302_residues
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDP
VLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQ
TNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAA
MSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH
>Mature_301_residues
TEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDPV
LVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQT
NILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAAM
SGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CRTB_MYCBO (P65861)

Other databases:

- EMBL:   BX248346
- RefSeq:   NP_857071.1
- ProteinModelPortal:   P65861
- SMR:   P65861
- EnsemblBacteria:   EBMYCT00000017627
- GeneID:   1090989
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3430c
- GeneTree:   EBGT00050000017775
- HOGENOM:   HBG693191
- OMA:   ADSDLPR
- ProtClustDB:   CLSK872176
- BioCyc:   MBOV233413:MB3430C-MONOMER
- BRENDA:   2.5.1.32
- InterPro:   IPR002060
- InterPro:   IPR017828
- InterPro:   IPR019845
- InterPro:   IPR008949
- Gene3D:   G3DSA:1.10.600.10
- TIGRFAMs:   TIGR03465

Pfam domain/function: PF00494 SQS_PSY; SSF48576 Terpenoid_synth

EC number: =2.5.1.32

Molecular weight: Translated: 33142; Mature: 33011

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1; PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETK
CCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDE
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCHHH
LIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPR
HHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
DELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAA
HHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
MSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SH
CC
>Mature Secondary Structure 
TEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETK
CCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDE
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCHHH
LIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPR
HHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
DELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAA
HHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
MSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972