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The map label for this gene is baiCD [H]

Identifier: 148824568

GI number: 148824568

Start: 3783810

End: 3785000

Strand: Direct

Name: baiCD [H]

Synonym: TBFG_13395

Alternate gene names: 148824568

Gene position: 3783810-3785000 (Clockwise)

Preceding gene: 148824567

Following gene: 148824569

Centisome position: 85.52

GC content: 67.34

Gene sequence:

>1191_bases
GTGGCTCCCGGCAGCTGCGAAGCCCCGGACGTGTTCAACCCGGCCAAACTCGGTCCGCTCACGCTGCGTAACCGGGTCAT
CAAGGCCGCCACCTTCGAGGCCCGCACACCTGACGCGTTGGTGACCGATGACCTGATCGAGTACCACCGGCTGCCGGCCG
CGGGCGGGGTCGCCATGACCACCGTCGCCTATTGCGCGGTCTCCCCCGGCGGACGCACCTGCGGCAACCAGATCTGGATG
CGCCCGCATGCGGTGCCGGGACTGCGCCGGCTCACCGAGGCGATACACGCCGAGGGGGCGGCGATCAGCGCCCAGATCGG
CCACGCCGGCCCGGTGGCCGACGCCCGCTCCAACCAGGCGACCGCGCTGGCTCCGGTGCGGTTCTTCAATCCGATCGCTA
TGCGGTTCGCCCAGAAGGCGACCCGCGAGGACATCGACGATGTGCTGGCCGCGCACGCCCATGCCGCCCGGCTGGCCGTC
GACGCCGGCTTCGACGCCGTCGAAATCCATTTGGGGCATAACTATCTGGCGAGCGCGTTTCTGTCTCCGCTGCTCAACCG
GCGTGATGACGAGTTCGGCGGTTCGTTGCAGAACCGGGCGAAGGTAGCTCGCGGATTGGTGATGGCCGTGCGCCGCGCCG
TCCGGCAGCAGGTCGCGGTGACCGCCAAGCTCAACATGACCGATGGCATCCGCGGCGGCATCACAGTCGACGAGGCACTG
ACCACCGCCAGGTGGCTGCAGGACGACGGCGGGCTAGACGCGATCGAGCTCACCGCGGGCAGCTCGCTGGTCAACCCGAT
GTATTTGTTCCGCGGCGACGCGCCGGTTAAGGAGTTCGCCGCCGCGTTCAAACCACCGCTGCGCTGGGGCATCCGGATGA
CCGGCCATAGGTTTTTCCGCGAATACCCCTACCGCGATGCCTATCTGTTACGCGAGGCTCGGTTGTTTCGCGCCGAGCTG
ACAATCCCGCTGATTCTGCTGGGCGGCATCACCAACCGAACGACCATGGACCTGGCGATGGCCGAAGGGTTCGAGTTCGT
CGCGATGGCTCGGGCGCTGCTCGCCGAGCCCGACCTGGTCAATCGGATCGCGGCCGAAGGCAGCCAGGTGCGGTCGGCGT
GCACACACTGTAATCAGTGCATGGCCACGATTTATCGCCGCACTCACTGTGTGGTCACCGGGGCTCCATAG

Upstream 100 bases:

>100_bases
TGGTGTATCGAGCGGGCGACGACGAAGTCACGATGCTGAAGGCCCGATACCACTACTGATTTGGGGGCTGGTGGTATTCC
GGCGGGCTTAAGCTCCCCAT

Downstream 100 bases:

>100_bases
CGTCCAGATTGACGCCACCGTGAAGAAGTGCAACCCATTGTGCCGGAAATCCGGTTGACTTCCCCGCGCGAATCCGGCTC
AGGCACTATTGACCGCGCGC

Product: oxidoreductase

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: Bile acid-inducible operon protein C; Bile acid-inducible operon protein D [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAPGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMTTVAYCAVSPGGRTCGNQIWM
RPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAV
DAGFDAVEIHLGHNYLASAFLSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEAL
TTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAEL
TIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLVNRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP

Sequences:

>Translated_396_residues
MAPGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMTTVAYCAVSPGGRTCGNQIWM
RPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAV
DAGFDAVEIHLGHNYLASAFLSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEAL
TTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAEL
TIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLVNRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP
>Mature_395_residues
APGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMTTVAYCAVSPGGRTCGNQIWMR
PHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAVD
AGFDAVEIHLGHNYLASAFLSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEALT
TARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAELT
IPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLVNRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP

Specific function: Catalyzes The NADP-Dependent Reduction Of 2,4-Dienoyl- CoA To Yield Trans-2- Enoyl-CoA. [C]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=395, Percent_Identity=26.8354430379747, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787939, Length=379, Percent_Identity=27.1767810026385, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=276, Percent_Identity=29.3478260869565, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=416, Percent_Identity=23.7980769230769, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=368, Percent_Identity=24.7282608695652, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=371, Percent_Identity=24.2587601078167, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=267, Percent_Identity=26.5917602996255, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=389, Percent_Identity=23.3933161953728, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540738, Length=275, Percent_Identity=26.5454545454545, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325086, Length=82, Percent_Identity=36.5853658536585, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR016040
- InterPro:   IPR001155
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 42882; Mature: 42751

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
TVAYCAVSPGGRTCGNQIWMRPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQA
HHHHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
TALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAF
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHH
LSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEAL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHH
TTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFR
HHHHHHHCCCCCCEEEEECCCCHHCCHHEEECCCCHHHHHHHHCCCHHHCHHHHHHHHHH
EYPYRDAYLLREARLFRAELTIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLV
HCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHH
NRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
APGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHH
TVAYCAVSPGGRTCGNQIWMRPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQA
HHHHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCC
TALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAF
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHH
LSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEAL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHH
TTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFR
HHHHHHHCCCCCCEEEEECCCCHHCCHHEEECCCCHHHHHHHHCCCHHHCHHHHHHHHHH
EYPYRDAYLLREARLFRAELTIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLV
HCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHH
NRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254270 [H]