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The map label for this gene is moaC

Identifier: 148824528

GI number: 148824528

Start: 3721372

End: 3721905

Strand: Reverse

Name: moaC

Synonym: TBFG_13355

Alternate gene names: 148824528

Gene position: 3721905-3721372 (Counterclockwise)

Preceding gene: 148824529

Following gene: 148824527

Centisome position: 84.12

GC content: 63.3

Gene sequence:

>534_bases
GTGAACGACCACGATGGGGTGCTTACCCACCTTGATGAACAAGGCGCCGCCCGAATGGTCGATGTGTCGGCGAAGGCGGT
GACCTTGCGGCGAGCGCGGGCATCCGGGGCCGTCCTGATGAAACCGTCGACCCTGGACATGATCTGTCACGGCACCGCGG
CAAAGGGCGATGTCATAGCGACCGCACGGATAGCCGGCATTATGGCGGCCAAACGGACCGGTGAGCTTATCCCGCTGTGT
CACCCGCTGGGGATCGAGGCGGTCACCGTCACGCTCGAGCCGCAGGGCGCGGACCGGCTCTCGATTGCGGCGACGGTGAC
CACGGTGGCACGTACGGGTGTGGAGATGGAGGCGTTGACCGCCGTTACGGTGACAGCGCTCACGGTTTACGACATGTGCA
AAGCAGTCGACCGTGCCATGACGATCACGGATATCAGATTGGACGAAAAAAGCGGTGGCCGATCGGGTCATTACCGGCGG
CACGACGCGGACGTCAAACCCAGCGATGGTGGCTCCACCGAGGATGGATGTTGA

Upstream 100 bases:

>100_bases
GTTGGACGCGCCAGATGCACTGTTTGACTCGCGTCGACTTCGACCTCGCCGAGGCTTTCAGCGCAGTGCACGATGAGCAA
TGCAGCCAGCAGGTGGCACG

Downstream 100 bases:

>100_bases
ATGATTACTGTCAATGTGCTCTACTTTGGCGCGGTTCGCGAAGCGTGCAAGGTCGCTCACGAGAAGATCTCACTCGAAAG
CGGCACCACCGTCGACGGCT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIATARIAGIMAAKRTGELIPLC
HPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALTAVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRR
HDADVKPSDGGSTEDGC

Sequences:

>Translated_177_residues
MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIATARIAGIMAAKRTGELIPLC
HPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALTAVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRR
HDADVKPSDGGSTEDGC
>Mature_177_residues
MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIATARIAGIMAAKRTGELIPLC
HPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALTAVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRR
HDADVKPSDGGSTEDGC

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=57.1428571428571, Blast_Score=159, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=44.078947368421, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=170, Percent_Identity=50.5882352941176, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI28574492, Length=159, Percent_Identity=49.685534591195, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC3_MYCBO (P65393)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_856998.2
- ProteinModelPortal:   P65393
- SMR:   P65393
- EnsemblBacteria:   EBMYCT00000015891
- GeneID:   1093734
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3353c
- GeneTree:   EBGT00050000016668
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   MBOV233413:MB3353C-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 18555; Mature: 18555

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIA
CCCCCCCEEEECCCCCEEEEECCHHEEEEEHHCCCCEEEECCCCEEEEEECCCCCCCEEE
TARIAGIMAAKRTGELIPLCHPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALT
HHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCHHHHH
AVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRRHDADVKPSDGGSTEDGC
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIA
CCCCCCCEEEECCCCCEEEEECCHHEEEEEHHCCCCEEEECCCCEEEEEECCCCCCCEEE
TARIAGIMAAKRTGELIPLCHPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALT
HHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCHHHHH
AVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRRHDADVKPSDGGSTEDGC
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972