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The map label for this gene is cdd [H]

Identifier: 148824519

GI number: 148824519

Start: 3715121

End: 3715522

Strand: Reverse

Name: cdd [H]

Synonym: TBFG_13346

Alternate gene names: 148824519

Gene position: 3715522-3715121 (Counterclockwise)

Preceding gene: 148824524

Following gene: 148824518

Centisome position: 83.98

GC content: 66.92

Gene sequence:

>402_bases
ATGCCTGATGTCGATTGGAATATGCTGCGGGGCAATGCAACCCAGGCAGCAGCCGGAGCCTATGTGCCGTATTCGCGGTT
TGCGGTGGGTGCGGCCGCACTGGTCGACGATGGTCGCGTGGTGACCGGATGCAACGTGGAAAACGTCTCGTATGGCTTGA
CTTTGTGCGCCGAATGTGCGGTGGTGTGCGCCCTGCATTCGACCGGCGGCGGCCGGCTGCTCGCGCTGGCCTGCGTCGAC
GGCCATGGATCCGTGCTGATGCCGTGCGGGCGATGCCGTCAGGTGCTGCTCGAACACGGGGGTTCCGAGCTACTGATCGA
CCATCCGGTGCGACCCCGCCGGCTCGGCGACCTGCTGCCCGACGCCTTCGGCCTCGACGACCTCCCCCGGGAACGCCGGT
GA

Upstream 100 bases:

>100_bases
CAGGTTGCCCGCGGTGTCGAACAGTCCGATCGGGATCGTGTGTGGATCCGGGGTTAGGCTGGCTTTTCTTAGTCGGCCCA
TCGACGAGCGGGGTTGCCGA

Downstream 100 bases:

>100_bases
CCGACTTCGCATTCGACGCCCCGACCGTCATCCGCACCAAACGTGACGGCGGCCGGTTGTCCGACGCCGCCATCGACTGG
GTCGTCAAGGCCTATACCGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECAVVCALHSTGGGRLLALACVD
GHGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLPDAFGLDDLPRERR

Sequences:

>Translated_133_residues
MPDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECAVVCALHSTGGGRLLALACVD
GHGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLPDAFGLDDLPRERR
>Mature_132_residues
PDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECAVVCALHSTGGGRLLALACVDG
HGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLPDAFGLDDLPRERR

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=127, Percent_Identity=36.2204724409449, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540514, Length=120, Percent_Identity=39.1666666666667, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551074, Length=134, Percent_Identity=39.5522388059701, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=140, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582741, Length=123, Percent_Identity=35.7723577235772, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920920, Length=132, Percent_Identity=34.8484848484849, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14072; Mature: 13941

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECA
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHEEECCCCEEECCCCCCCHHHHHHHHHHH
VVCALHSTGGGRLLALACVDGHGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLP
HHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHCC
DAFGLDDLPRERR
CCCCCCCCCCCCC
>Mature Secondary Structure 
PDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECA
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHEEECCCCEEECCCCCCCHHHHHHHHHHH
VVCALHSTGGGRLLALACVDGHGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLP
HHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCHHHHHHCC
DAFGLDDLPRERR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]