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The map label for this gene is lrp [C]

Identifier: 148824493

GI number: 148824493

Start: 3683560

End: 3684012

Strand: Reverse

Name: lrp [C]

Synonym: TBFG_13320

Alternate gene names: 148824493

Gene position: 3684012-3683560 (Counterclockwise)

Preceding gene: 148824496

Following gene: 148824492

Centisome position: 83.27

GC content: 61.15

Gene sequence:

>453_bases
ATGAACGAGGCGCTCGACGATATCGATCGGATCCTGGTGCGCGAACTGGCCGCCGACGGACGTGCGACGCTGTCAGAGTT
GGCCACGCGAGCCGGGCTGTCGGTCTCGGCGGTCCAATCGCGAGTGCGCCGGCTGGAGTCTCGTGGTGTGGTCCAGGGAT
ATTCGGCGCGAATCAATCCCGAGGCGGTTGGGCATTTGTTGTCGGCGTTCGTGGCTATCACTCCTCTTGATCCGTCTCAA
CCAGATGATGCCCCCGCGCGCCTAGAACATATCGAGGAGGTCGAGTCCTGTTACTCGGTGGCCGGCGAAGAGAGCTACGT
CTTGCTGGTGCGCGTCGCGTCCGCACGGGCGCTCGAGGACCTGTTGCAACGGATCCGGACAACGGCGAACGTGCGGACGC
GAAGCACGATCATTCTGAACACTTTTTACAGCGATAGGCAGCATATACCATAA

Upstream 100 bases:

>100_bases
ACATGGCTGACAACCCGGCGGCGAAGCGCGCGCGCAGCTGGCCAGTCTGCAGTCTTTTCGAGCGGCTCATGCGGCACTGC
CGTTGCGATAGTCTCCGGCC

Downstream 100 bases:

>100_bases
TTTTTCCAGCATAAATATCAATATTCCGTAAATCCTGCTATCATAGCGTCATGGCCGCCGTCGTGAAGTCCGTCGCTCTT
GCCGGTAGACCAACAACACC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQ
PDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP

Sequences:

>Translated_150_residues
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQ
PDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP
>Mature_150_residues
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQ
PDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQRIRTTANVRTRSTIILNTFYSDRQHIP

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=121, Percent_Identity=40.495867768595, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1790182, Length=139, Percent_Identity=26.6187050359712, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16511; Mature: 16511

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINP
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
EAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALED
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
LLQRIRTTANVRTRSTIILNTFYSDRQHIP
HHHHHHHHHCCCHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MNEALDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINP
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCH
EAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALED
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
LLQRIRTTANVRTRSTIILNTFYSDRQHIP
HHHHHHHHHCCCHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]