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The map label for this gene is manB [H]

Identifier: 148824459

GI number: 148824459

Start: 3649090

End: 3650487

Strand: Reverse

Name: manB [H]

Synonym: TBFG_13286

Alternate gene names: 148824459

Gene position: 3650487-3649090 (Counterclockwise)

Preceding gene: 148824460

Following gene: 148824458

Centisome position: 82.51

GC content: 64.81

Gene sequence:

>1398_bases
ATGTCTTGGCCCGCCGCGGCTGTGGACCGCGTTATCAAGGCTTACGACGTACGCGGGCTGGTCGGCGAAGAGATCGACGA
GTCGCTGGTTACCGATCTCGGCGCCGCATTCGCGCGGTTGATGCGGACCGAGGATGCGCGACCAGTGGTGATCGGTCACG
ACATGCGGGACAGTTCGCCGTCGCTGGCCGACGCGTTCGCGGCCGGGGTGACCGGGCAGGGCCTCGACGTGGTGCGAGTT
GGTTTGGCGTCCACCGATCAGCTTTATTTCGCCTCGGGGCTGTTGGACTGCCCGGGAGCGATGTTCACCGCGAGCCACAA
CCCGGCGGCATACAACGGCATCAAGATGTGTCGGGCCGCCGCCAAACCAGTCGGAGCCGATACCGGGCTGACCGCCATCC
GTGACGACCTGATCGCCGGCGTCGCACGATACGACGGGACGCCCGGAACCATTGCCGACCAGGACGTGCTGGTCGACTAC
GGGGCGTTCCTGCGATCGCTGGTGGACACCTCGGGGCTACGTCCGTTGCGGGTGGCCGTGGACGCCGGCAACGGCATGGC
CGGTCACACCGCGCCGGCGGTCCTTGGGGTGATCGACTCGATCACCTTGTTGCCCTCGTATTTTGAGCTCGACGGATCGT
TTCCCAATCACGAGGCCAATCCGCTGGACCCGGCGAACCTGGTGGATCTGCAGGCCTATGTGCGTGACACCGGCGCCGAT
ATCGGGCTTGCTTTCGACGGCGACGCCGACCGCTGCTTCGTGGTCGACGAACGCGGCCAGCCGGTCTCGCCGTCGACGGT
TACCGCATTGGTGGCCGCGCGGGAACTCAACCGGGAGATCGGCGCCACCATCATCCACAACGTGATCACCTCCCGCGCGG
TGCCCGAGCTGGTCGCCGAGCGCGGCGGTACGCCGCTGCGTTCGCGGGTTGGGCACTCCTATATCAAGGCACTGATGGCC
GAGACCGGGGCGATTTTCGGTGGTGAACATTCGGCGCACTATTACTTCCGTGACTTCTGGGGTGCCGATTCCGGAATGCT
GGCCGCACTGCATGTGCTGGCCGCCCTCGGTGAGCAGAGCAGACCGCTGTCGGAGTTGACCGCGGACTACCAACGCTATG
AATCCTCCGGCGAGATCAACTTCACCGTGGTCGACTCTTCGGCCTGTGTGGAGGCCGTGTTGAAATCGTTCGGCAACCGG
ATTGTCAGTATTGATCACCTCGATGGCGTGACCGTTGACTTAGGCGACGACAGCTGGTTCAACCTGCGCAGCTCAAACAC
CGAGCCGTTGCTGCGGCTCAATGTGGAGGGCCGCAGCGTCGGGGACGTTGACGCGGTGGTACGTCAGGTCAGCGCTGAAA
TCGCTGCCCAGAGCGCACATGCGAAGGCCGGACCGTGA

Upstream 100 bases:

>100_bases
CTTCCCATGCTGTTCGAGACCGATTCGGCCCGCGTCGTTCGCGGGCCGATAGGCTGGCGGCCAAGAGTCGCAGAAAATCT
AGGTTGTCAGGAGCCCGCGC

Downstream 100 bases:

>100_bases
ACGTCGCCCGGGCGATCGATCTCGAGGACACCGAAGGCCTGATCGCTGCCGACCGGGGTGCCCTGCTGCGGGCCGCATCG
ATGGCCGGCGCACAGGTGCG

Product: phosphomannomutase/phosphoglucomutase

Products: NA

Alternate protein names: Phosphoglucomutase; PGM; Glucose phosphomutase; Phosphomannomutase; PMM [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSWPAAAVDRVIKAYDVRGLVGEEIDESLVTDLGAAFARLMRTEDARPVVIGHDMRDSSPSLADAFAAGVTGQGLDVVRV
GLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKMCRAAAKPVGADTGLTAIRDDLIAGVARYDGTPGTIADQDVLVDY
GAFLRSLVDTSGLRPLRVAVDAGNGMAGHTAPAVLGVIDSITLLPSYFELDGSFPNHEANPLDPANLVDLQAYVRDTGAD
IGLAFDGDADRCFVVDERGQPVSPSTVTALVAARELNREIGATIIHNVITSRAVPELVAERGGTPLRSRVGHSYIKALMA
ETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALGEQSRPLSELTADYQRYESSGEINFTVVDSSACVEAVLKSFGNR
IVSIDHLDGVTVDLGDDSWFNLRSSNTEPLLRLNVEGRSVGDVDAVVRQVSAEIAAQSAHAKAGP

Sequences:

>Translated_465_residues
MSWPAAAVDRVIKAYDVRGLVGEEIDESLVTDLGAAFARLMRTEDARPVVIGHDMRDSSPSLADAFAAGVTGQGLDVVRV
GLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKMCRAAAKPVGADTGLTAIRDDLIAGVARYDGTPGTIADQDVLVDY
GAFLRSLVDTSGLRPLRVAVDAGNGMAGHTAPAVLGVIDSITLLPSYFELDGSFPNHEANPLDPANLVDLQAYVRDTGAD
IGLAFDGDADRCFVVDERGQPVSPSTVTALVAARELNREIGATIIHNVITSRAVPELVAERGGTPLRSRVGHSYIKALMA
ETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALGEQSRPLSELTADYQRYESSGEINFTVVDSSACVEAVLKSFGNR
IVSIDHLDGVTVDLGDDSWFNLRSSNTEPLLRLNVEGRSVGDVDAVVRQVSAEIAAQSAHAKAGP
>Mature_464_residues
SWPAAAVDRVIKAYDVRGLVGEEIDESLVTDLGAAFARLMRTEDARPVVIGHDMRDSSPSLADAFAAGVTGQGLDVVRVG
LASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKMCRAAAKPVGADTGLTAIRDDLIAGVARYDGTPGTIADQDVLVDYG
AFLRSLVDTSGLRPLRVAVDAGNGMAGHTAPAVLGVIDSITLLPSYFELDGSFPNHEANPLDPANLVDLQAYVRDTGADI
GLAFDGDADRCFVVDERGQPVSPSTVTALVAARELNREIGATIIHNVITSRAVPELVAERGGTPLRSRVGHSYIKALMAE
TGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALGEQSRPLSELTADYQRYESSGEINFTVVDSSACVEAVLKSFGNRI
VSIDHLDGVTVDLGDDSWFNLRSSNTEPLLRLNVEGRSVGDVDAVVRQVSAEIAAQSAHAKAGP

Specific function: Involved in xanthan production [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=445, Percent_Identity=37.3033707865169, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=27.5167785234899, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 49041; Mature: 48910

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWPAAAVDRVIKAYDVRGLVGEEIDESLVTDLGAAFARLMRTEDARPVVIGHDMRDSSP
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SLADAFAAGVTGQGLDVVRVGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKMCRAA
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHH
AKPVGADTGLTAIRDDLIAGVARYDGTPGTIADQDVLVDYGAFLRSLVDTSGLRPLRVAV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DAGNGMAGHTAPAVLGVIDSITLLPSYFELDGSFPNHEANPLDPANLVDLQAYVRDTGAD
ECCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IGLAFDGDADRCFVVDERGQPVSPSTVTALVAARELNREIGATIIHNVITSRAVPELVAE
EEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGTPLRSRVGHSYIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALGEQS
CCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCC
RPLSELTADYQRYESSGEINFTVVDSSACVEAVLKSFGNRIVSIDHLDGVTVDLGDDSWF
CCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEE
NLRSSNTEPLLRLNVEGRSVGDVDAVVRQVSAEIAAQSAHAKAGP
ECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWPAAAVDRVIKAYDVRGLVGEEIDESLVTDLGAAFARLMRTEDARPVVIGHDMRDSSP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
SLADAFAAGVTGQGLDVVRVGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKMCRAA
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHH
AKPVGADTGLTAIRDDLIAGVARYDGTPGTIADQDVLVDYGAFLRSLVDTSGLRPLRVAV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DAGNGMAGHTAPAVLGVIDSITLLPSYFELDGSFPNHEANPLDPANLVDLQAYVRDTGAD
ECCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
IGLAFDGDADRCFVVDERGQPVSPSTVTALVAARELNREIGATIIHNVITSRAVPELVAE
EEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGGTPLRSRVGHSYIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALGEQS
CCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCC
RPLSELTADYQRYESSGEINFTVVDSSACVEAVLKSFGNRIVSIDHLDGVTVDLGDDSWF
CCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEE
NLRSSNTEPLLRLNVEGRSVGDVDAVVRQVSAEIAAQSAHAKAGP
ECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280 [H]