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The map label for this gene is thiL [H]

Identifier: 148824167

GI number: 148824167

Start: 3344260

End: 3345261

Strand: Reverse

Name: thiL [H]

Synonym: TBFG_12992

Alternate gene names: 148824167

Gene position: 3345261-3344260 (Counterclockwise)

Preceding gene: 148824168

Following gene: 148824166

Centisome position: 75.61

GC content: 69.56

Gene sequence:

>1002_bases
GTGACCACTAAAGATCACTCACTTGCAACGGAGTCCCCGACGCTGCAGCAGCTCGGCGAGTTCGCCGTGATCGACCGGCT
GGTGCGGGGGCGCCGACAACCCGCCACGGTACTGCTCGGGCCCGGCGACGATGCCGCGCTGGTGTCTGCCGGCGATGGTC
GCACTGTGGTGTCGACGGACATGCTGGTGCAAGATAGTCACTTCCGGCTGGACTGGTCGACACCGCAGGACGTCGGCCGC
AAGGCGATCGCCCAGAATGCCGCCGACATCGAGGCGATGGGGGCGCGGGCCACCGCGTTCGTGGTCGGCTTTGGAGCACC
CGCTGAGACGCCGGCGGCGCAGGCGAGCGCGTTGGTCGACGGAATGTGGGAGGAGGCGGGGCGCATTGGTGCCGGCATCG
TCGGCGGCGATCTGGTCAGCTGCCGGCAGTGGGTGGTGTCGGTCACCGCGATTGGTGACCTTGACGGTCGTGCCCCGGTG
CTGCGCTCCGGGGCGAAGGCCGGCTCGGTGCTGGCCGTCGTCGGTGAGCTGGGCCGCTCGGCTGCTGGCTATGCGCTGTG
GTGCAACGGGATTGAAGACTTCGCCGAACTGCGCCGCCGCCATTTGGTGCCGCAGCCGCCCTACGGCCACGGCGCGGCGG
CCGCGGCTGTCGGGGCTCAAGCGATGATCGATGTCTCCGACGGGCTGCTCGCCGATCTGCGGCACATCGCCGAGGCATCC
GGCGTGCGCATCGACCTGTCCGCCGCGGCGTTGGCCGCTGACCGCGACGCTTTGACTGCGGCCGCAACCGCTCTGGGCAC
CGACCCCTGGCCGTGGGTGCTAAGCGGGGGTGAAGATCATGCCCTGGTCGCCTGTTTCGTCGGTCCGGTGCCGGCCGGGT
GGCGCACCATTGGCCGGGTTCTCGACGGGCCGGCTAGGGTGCTGGTCGACGGCGAGGAGTGGACTGGATACGCGGGCTGG
CAATCGTTTGGGGAGCCAGACAATCAAGGTTCGCTAGGGTGA

Upstream 100 bases:

>100_bases
CCGACCGTAAGACCGGGCCTCGCCCGGCAGGTGGCTGTGAAGCGCGGAAGGGAAGCAGCCCCAAGGCTGCCGAACAACCC
CGAGACGGGGTGCAAGTCGC

Downstream 100 bases:

>100_bases
CGCGGTGACCGTCTGTACGCGAAAGGGATGCAGTGACCGCACGGCCGTTGAGTGAGCTCGTCGAGCGGGGGTGGGCCGCC
GCGCTCGAGCCGGTGGCCGA

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGR
KAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPV
LRSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEAS
GVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGW
QSFGEPDNQGSLG

Sequences:

>Translated_333_residues
MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGR
KAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPV
LRSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEAS
GVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGW
QSFGEPDNQGSLG
>Mature_332_residues
TTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTDMLVQDSHFRLDWSTPQDVGRK
AIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVDGMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVL
RSGAKAGSVLAVVGELGRSAAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEASG
VRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRVLDGPARVLVDGEEWTGYAGWQ
SFGEPDNQGSLG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=282, Percent_Identity=36.8794326241135, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34331; Mature: 34200

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEEC
MLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVD
EEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHH
GMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVLRSGAKAGSVLAVVGELGRS
HHHHHHCCCCCCCCCCHHHHHHHHHEEHEEECCCCCCCHHHHCCCCCCHHHHHHHHHCCC
AAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEAS
CCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHC
GVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRV
CCEEEEHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHH
LDGPARVLVDGEEWTGYAGWQSFGEPDNQGSLG
HCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTKDHSLATESPTLQQLGEFAVIDRLVRGRRQPATVLLGPGDDAALVSAGDGRTVVSTD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEEC
MLVQDSHFRLDWSTPQDVGRKAIAQNAADIEAMGARATAFVVGFGAPAETPAAQASALVD
EEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHH
GMWEEAGRIGAGIVGGDLVSCRQWVVSVTAIGDLDGRAPVLRSGAKAGSVLAVVGELGRS
HHHHHHCCCCCCCCCCHHHHHHHHHEEHEEECCCCCCCHHHHCCCCCCHHHHHHHHHCCC
AAGYALWCNGIEDFAELRRRHLVPQPPYGHGAAAAAVGAQAMIDVSDGLLADLRHIAEAS
CCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHC
GVRIDLSAAALAADRDALTAAATALGTDPWPWVLSGGEDHALVACFVGPVPAGWRTIGRV
CCEEEEHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHH
LDGPARVLVDGEEWTGYAGWQSFGEPDNQGSLG
HCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]