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The map label for this gene is 148824148

Identifier: 148824148

GI number: 148824148

Start: 3323574

End: 3324311

Strand: Reverse

Name: 148824148

Synonym: TBFG_12973

Alternate gene names: NA

Gene position: 3324311-3323574 (Counterclockwise)

Preceding gene: 148824149

Following gene: 148824147

Centisome position: 75.14

GC content: 53.66

Gene sequence:

>738_bases
ATGGGGCTAGTGTGGCGCAGTCGGACTAGTCTTGTAGGGCAACTGATCGGACTAGTCAGGTTAGTGGCGAGTTTTGCGGC
CCAGTTATTCTACCGGCCGAGCGACGCAGTGGCGGAAGAATACCACAAGTGGTACTACGGCAACTTAGTGTGGACGAAGA
CCACTTATATGGGGATCAATTGCTGGAAATCCGTCAGCGATATGTGGAATTACCAGGAGATCCTGAGCGAGTTGCAACCA
TCCCTCGTCATCGAGTTCGGCACCCGCTACGGCGGCTCGGCGGTGTATTTTGCCAACATCATGAGGCAGATCGGCCAGCC
ATTCAAGGTACTTACCGTGGACAACTCACACAAAGCCCTCGATCCAAGAGCCCGGCGCGAACCAGATGTTTTGTTCGTTG
AATCGTCATCCACCGACCCGGCGATTGCCGAACAAATTCAACGCCTCAAAAACGAATACCCTGGCAAGATCTTCGCCATC
TTAGATAGCGACCACTCGATGAATCATGTGCTGGCCGAGATGAAATTACTACGGCCGCTACTCTCCGCCGGTGACTACCT
AGTAGTCGAGGATTCCAACATCAACGGCCACCCAGTCCTGCCCGGGTTTGGGCCTGGACCCTATGAAGCGATCGAGGCAT
ATGAGGATGAATTTCCAAACGATTACAAGCATGATGCGGAGCGGGAGAACAAATTCGGCTGGACTTCCGCGCCCAACGGA
TTTCTGATCCGCAACTAG

Upstream 100 bases:

>100_bases
CATGTATTGAGTCCGCTTCGACCTCATCAGTTCTCTTAAAGAGGCTTGCTAAATGACCAACATTCGACTGACTACGGTTT
CGCAGTGAGGAGATGATGGA

Downstream 100 bases:

>100_bases
CGGTCGGTGTGAGAAATAGCTCGACGCATTGCATTTTGGGGGATTGCATTTTTGGGAGGTTGCCTGCGGGTACGGGCTGC
CTCGAGATTAGGGGGCGAGT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQP
SLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAI
LDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNG
FLIRN

Sequences:

>Translated_245_residues
MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQP
SLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAI
LDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNG
FLIRN
>Mature_244_residues
GLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPS
LVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAIL
DSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGF
LIRN

Specific function: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD)

COG id: COG3510

COG function: function code V; Cephalosporin hydroxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rhamnosyl O-methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNMT_MYCBO (Q7TXJ7)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856628.1
- ProteinModelPortal:   Q7TXJ7
- EnsemblBacteria:   EBMYCT00000016692
- GeneID:   1093888
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2983c
- GeneTree:   EBGT00050000018653
- HOGENOM:   HBG336035
- OMA:   DEARECK
- ProtClustDB:   CLSK792190
- BioCyc:   MBOV233413:MB2983C-MONOMER
- InterPro:   IPR007072

Pfam domain/function: PF04989 CmcI

EC number: NA

Molecular weight: Translated: 27845; Mature: 27714

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGIN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECHH
CWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKAL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
DPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
LSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNG
HCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
FLIRN
CEECC
>Mature Secondary Structure 
GLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECHH
CWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKAL
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
DPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
LSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNG
HCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
FLIRN
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972