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The map label for this gene is pbpA [H]

Identifier: 148824055

GI number: 148824055

Start: 3186984

End: 3188795

Strand: Reverse

Name: pbpA [H]

Synonym: TBFG_12880

Alternate gene names: 148824055

Gene position: 3188795-3186984 (Counterclockwise)

Preceding gene: 148824058

Following gene: 148824053

Centisome position: 72.07

GC content: 66.78

Gene sequence:

>1812_bases
ATGGTAACTAAAACAACATTAGCCTCAGCCACCTCAGGTTTGCTGCTGCTTGCGGTCGTCGCCATGTCGGGCTGCACCCC
GCGTCCCCAAGGGCCCGGTCCGGCGGCCGAAAAGTTCTTCGCCGCGCTGGCCATCGGTGACACCGCCTCCGCCGCCCAGC
TCAGCGACAACCCCAACGAGGCGCGCGAAGCGCTGAACGCGGCCTGGGCGGGGCTGCAGGCCGCCCACCTGGATGCGCAG
GTTCTCAGCGCCAAGTACGCCGAGGACACCGGTACGGTCGCTTATCGCTTCAGCTGGCATCTGCCCAAGGACCGAATCTG
GACCTATGACGGCCAGCTGAAGATGGCCCGCGACGAAGGGCGTTGGCACGTTCGCTGGACCACCAGCGGGTTGCATCCCA
AGCTAGGCGAACATCAAACGTTCGCGCTACGAGCCGACCCGCCGCGGCGCGCCTCGGTGAACGAAGTCGGCGGCACCGAT
GTGCTGGTGCCGGGCTATCTGTATCACTACTCGCTGGACGCCGGCCAGGCCGGCCGCGAGCTCTTCGGCACGGCACACGC
GGTGGTGGGCGCGCTGCACCCCTTCGACGACACGCTCAATGATCCGCAGCTGCTGGCCGAACAGGCCAGCTCGTCGACCC
AGCCGTTGGACCTGGTCACGTTGCACGCCGACGACAGCAACCGGGTGGCCGCGGCGATCGGGCAGCTGCCTGGCGTGGTG
ATCACACCGCAGGCCGAGCTGCTCCCGACCGACAAGCACTTCGCGCCGGCGGTCCTCAACGATGTCAAGAAGGCCGTCGT
CGATGAACTCGACGGCAAGGCGGGTTGGCGGGTGGTGAGCGTCAACCAAAATGGCGTCGACGTCTCGGTGCTGCACGAGG
TCGCCCCATCACCTGCGTCGTCGGTTTCGATCACGTTGGATCGGGTCGTGCAAAACGCCGCGCAACACGCGGTGAACACC
CGGGGCGGCAAGGCGATGATCGTCGTGATCAAGCCGTCGACCGGCGAGATCCTGGCGATCGCGCAGAACGCCGGGGCCGA
TGCGGACGGTCCGGTCGCGACCACCGGTCTATATCCACCCGGGTCGACATTCAAGATGATCACCGCCGGTGCGGCCGTCG
AGCGTGACCTGGCTACCCCTGAGACGCTGCTGGGTTGCCCCGGGGAGATCGACATCGGGCATCGCACCATTCCCAACTAC
GGTGGCTTTGATCTGGGCGTGGTGCCGATGTCACGCGCGTTTGCCAGTTCCTGCAACACCACCTTCGCCGAGCTGAGCAG
CAGGCTGCCTCCCCGCGGTCTGACTCAGGCGGCCCGGCGGTACGGGATCGGGCTTGACTACCAGGTGGACGGCATCACCA
CGGTGACCGGTTCGGTGCCGCCGACGGTGGACCTGGCCGAACGCACCGAGGACGGTTTCGGCCAGGGCAAGGTGCTGGCC
AGCCCGTTCGGCATGGCCTTGGTGGCGGCGACGGTAGCCGCCGGGAAGACCCCGGTTCCACAGCTGATCGCCGGCCGGCC
GACGGCCGTCGAAGGCGATGCCACACCGATCAGCCAGAAGATGGTCGACGCGCTGCGGCCCATGATGCGGTTGGTGGTGA
CCAATGGCACCGCCAAGGAGATCGCTGGCTGTGGCGAGGTGTTCGGTAAGACCGGCGAAGCCGAATTCCCGGGCGGATCG
CATTCCTGGTTCGCCGGGTACCGTGGCGATCTGGCATTTGCGTCGCTGATCGTCGGGGGCGGTAGCTCGGAATACGCGGT
GCGGATGACCAAGGTGATGTTCGAATCGCTGCCGCCGGGGTACCTGGCGTAG

Upstream 100 bases:

>100_bases
TTCGCGGTGGTGTTCCATTCGCGACCTAGTCTCGGCGTAACGGTTCGGTCTCGGTGTGTCGCGGCCGGTGTCTCCGTCAC
AGTTCTTAACATCAGCAACG

Downstream 100 bases:

>100_bases
CGCGGCTCGCCCCTCCTCGTTTGTACGACGACACGCCGTTAGGGCCGTACAACTGCGGACGCTCGCGCCCACACGGACGC
GTCATGATCGGAATGCGCTG

Product: penicillin-binding lipoprotein

Products: NA

Alternate protein names: PBPA [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMVDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA

Sequences:

>Translated_603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMVDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA
>Mature_603_residues
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNEAREALNAAWAGLQAAHLDAQ
VLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEGRWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTD
VLVPGYLYHYSLDAGQAGRELFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPASSVSITLDRVVQNAAQHAVNT
RGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPPGSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNY
GGFDLGVVPMSRAFASSCNTTFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMVDALRPMMRLVVTNGTAKEIAGCGEVFGKTGEAEFPGGS
HSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPGYLA

Specific function: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Probable). Note=Localized to the division site (septum) along with newly synthesized peptidoglycan, between segregated nucleoids (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=293, Percent_Identity=24.9146757679181, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 63001; Mature: 63001

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHCCCCHHH
AREALNAAWAGLQAAHLDAQVLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEECCC
RWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTDVLVPGYLYHYSLDAGQAGRE
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCHH
LFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEE
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPAS
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC
SVSITLDRVVQNAAQHAVNTRGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPP
CEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCCC
GSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNYGGFDLGVVPMSRAFASSCNT
CCCEEEEECCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCH
TFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
HHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCHHHHCCCCCCCCCEEE
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMVDALRPMMRLVVTNGTAKE
CCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IAGCGEVFGKTGEAEFPGGSHSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
YLA
CCC
>Mature Secondary Structure
MVTKTTLASATSGLLLLAVVAMSGCTPRPQGPGPAAEKFFAALAIGDTASAAQLSDNPNE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCCCCHHCCCCHHH
AREALNAAWAGLQAAHLDAQVLSAKYAEDTGTVAYRFSWHLPKDRIWTYDGQLKMARDEG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCEEEEEECCC
RWHVRWTTSGLHPKLGEHQTFALRADPPRRASVNEVGGTDVLVPGYLYHYSLDAGQAGRE
EEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCHH
LFGTAHAVVGALHPFDDTLNDPQLLAEQASSSTQPLDLVTLHADDSNRVAAAIGQLPGVV
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEE
ITPQAELLPTDKHFAPAVLNDVKKAVVDELDGKAGWRVVSVNQNGVDVSVLHEVAPSPAS
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC
SVSITLDRVVQNAAQHAVNTRGGKAMIVVIKPSTGEILAIAQNAGADADGPVATTGLYPP
CEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCCC
GSTFKMITAGAAVERDLATPETLLGCPGEIDIGHRTIPNYGGFDLGVVPMSRAFASSCNT
CCCEEEEECCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCH
TFAELSSRLPPRGLTQAARRYGIGLDYQVDGITTVTGSVPPTVDLAERTEDGFGQGKVLA
HHHHHHHCCCCCHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCHHHHCCCCCCCCCEEE
SPFGMALVAATVAAGKTPVPQLIAGRPTAVEGDATPISQKMVDALRPMMRLVVTNGTAKE
CCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IAGCGEVFGKTGEAEFPGGSHSWFAGYRGDLAFASLIVGGGSSEYAVRMTKVMFESLPPG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
YLA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA