Click here to switch to the map view.

The map label for this gene is norM [H]

Identifier: 148824026

GI number: 148824026

Start: 3153947

End: 3155257

Strand: Reverse

Name: norM [H]

Synonym: TBFG_12851

Alternate gene names: 148824026

Gene position: 3155257-3153947 (Counterclockwise)

Preceding gene: 148824027

Following gene: 148824025

Centisome position: 71.31

GC content: 68.95

Gene sequence:

>1311_bases
GTGGGGCACCGCGCGGGCGGCCGTCAGATCGCGCAGCTGGCGTTGCCCGCGCTGGGCGTGCTGGCCGCCGAGCCGCTGTA
CCTGCTGTTCGACATCGCCGTGGTGGGCCGGCTGGGGGCGATATCGCTGGCGGGTCTGGCTATCGGCAGTCTGGTGCTCG
GCCTGGTTGGTTCCCAGGCGACGTTTTTGTCCTACGGCACCACAGCGCGCGCGGCGCGTCGTTACGGTGCCGGCAACCGG
GTGGCCGCGGTCACCGAAGGTGTACAGGCGACCTGGTTGGCGTTGGGTCTGGGCGCGTTGGTCGTCGTCGTGGTGGAAGC
CACCGCGACGCCGCTGGTGTCGGCGATCGCTTCTGGCGATGGCATCACCGCGGCGGCCTTGCCGTGGCTGCGGATCGCGA
TCCTGGGCACGCCGGCGATCCTGGTCTCGCTCGCCGGCAACGGCTGGCTGCGCGGCGTGCAGGACACCGTGCGACCGCTG
CGGTATGTGGTCGCCGGCTTCGGGTCGTCGGCTCTGCTGTGCCCGCTGCTGGTTTACGGTTGGCTGGGGTTGCCCCGCTG
GGGGTTAACCGGCTCGGCGGTGGCCAATCTGGTGGGGCAGTGGCTGGCGGCGCTGCTGTTTGCCGGTGCGTTACTGGCCG
AGCGGGTGTCGCTGCGGCCGGACCGCGCCGTGCTGGGCGCCCAGCTGATGATGGCGCGGGACCTGATCGTGCGGACCCTG
GCCTTCCAAGTTTGTTATGTCTCGGCTGCGGCGGTGGCCGCGAGGTTCGGCGCTGCCGCGCTCGCGGCCCACCAGGTCGT
GTTGCAGTTGTGGGGTCTTCTTGCGCTGGTTCTTGATTCGCTAGCGATTGCGGCGCAGTCGCTGGTCGGTGCCGCGTTGG
GTGCCGGTGATGCCGGGCACGCTAAGGCGGTGGCATGGCGGGTGACGGCGTTTTCGCTGTTGGCGGCGGGAATTTTGGCA
GCGGCGTTAGGGCTAGGCTCCTCGGTGCTGCCCGGGCTATTCACCGACGATCGATCGGTACTCGCCGCGATCGGGGTGCC
GTGGTGGTTCATGGTAGTCCAATTGCCTTTTGCGGGAATTGTTTTCGCAGTTGACGGGGTGCTGCTGGGCGCGGGCGACG
CCGCGTTCATGCGGACGGCGACGGTGGCGAGTGCGTTGGTGGGCTTTTTGCCGCTTGTCTGGTTGTCGCTGGCGTATGGC
TGGGGGCTGGCGGGTATCTGGTCGGGACTGGGCACGTTTATCGTGCTGCGGCTGATATTCGTCGGATGGCGGGCGTACAG
CGGTCGGTGGGCGGTGACGGGCGCGGCGTAG

Upstream 100 bases:

>100_bases
CGGTGGTCACCGGCTGGCCGCGGGGTATACGACCACCGGCTCGATCGACGACGCTGTGGCGTCGTTGCGCGCGGCGCTTG
GTTAGCCGCCGTTGAGCCAG

Downstream 100 bases:

>100_bases
CTGGCCGACATTGCCGTGACGGCGGTGATTGGTTCATCGACCGTGGCGGCAAACTCGCCGACAGAATACGGAGCTACACT
GCGCCGATGGCGGCGCCGCA

Product: DNA-damage-inducible protein F dinF

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYGTTARAARRYGAGNR
VAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDGITAAALPWLRIAILGTPAILVSLAGNGWLRGVQDTVRPL
RYVVAGFGSSALLCPLLVYGWLGLPRWGLTGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRTL
AFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVLDSLAIAAQSLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILA
AALGLGSSVLPGLFTDDRSVLAAIGVPWWFMVVQLPFAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYG
WGLAGIWSGLGTFIVLRLIFVGWRAYSGRWAVTGAA

Sequences:

>Translated_436_residues
MGHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYGTTARAARRYGAGNR
VAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDGITAAALPWLRIAILGTPAILVSLAGNGWLRGVQDTVRPL
RYVVAGFGSSALLCPLLVYGWLGLPRWGLTGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRTL
AFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVLDSLAIAAQSLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILA
AALGLGSSVLPGLFTDDRSVLAAIGVPWWFMVVQLPFAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYG
WGLAGIWSGLGTFIVLRLIFVGWRAYSGRWAVTGAA
>Mature_435_residues
GHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQATFLSYGTTARAARRYGAGNRV
AAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGDGITAAALPWLRIAILGTPAILVSLAGNGWLRGVQDTVRPLR
YVVAGFGSSALLCPLLVYGWLGLPRWGLTGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRTLA
FQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVLDSLAIAAQSLVGAALGAGDAGHAKAVAWRVTAFSLLAAGILAA
ALGLGSSVLPGLFTDDRSVLAAIGVPWWFMVVQLPFAGIVFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYGW
GLAGIWSGLGTFIVLRLIFVGWRAYSGRWAVTGAA

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=448, Percent_Identity=27.9017857142857, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI226510954, Length=444, Percent_Identity=22.972972972973, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 44442; Mature: 44311

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQA
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TFLSYGTTARAARRYGAGNRVAAVTEGVQATWLALGLGALVVVVVEATATPLVSAIASGD
HHHCCCCHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GITAAALPWLRIAILGTPAILVSLAGNGWLRGVQDTVRPLRYVVAGFGSSALLCPLLVYG
CCHHHHHHHHHHHHHCCHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
WLGLPRWGLTGSAVANLVGQWLAALLFAGALLAERVSLRPDRAVLGAQLMMARDLIVRTL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AFQVCYVSAAAVAARFGAAALAAHQVVLQLWGLLALVLDSLAIAAQSLVGAALGAGDAGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKAVAWRVTAFSLLAAGILAAALGLGSSVLPGLFTDDRSVLAAIGVPWWFMVVQLPFAGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHH
VFAVDGVLLGAGDAAFMRTATVASALVGFLPLVWLSLAYGWGLAGIWSGLGTFIVLRLIF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VGWRAYSGRWAVTGAA
HHHHHCCCCEEEECCC
>Mature Secondary Structure 
GHRAGGRQIAQLALPALGVLAAEPLYLLFDIAVVGRLGAISLAGLAIGSLVLGLVGSQA
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH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HHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]