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The map label for this gene is ycdJ [C]

Identifier: 148823904

GI number: 148823904

Start: 3040053

End: 3041078

Strand: Direct

Name: ycdJ [C]

Synonym: TBFG_12729

Alternate gene names: 148823904

Gene position: 3040053-3041078 (Clockwise)

Preceding gene: 148823903

Following gene: 148823905

Centisome position: 68.71

GC content: 63.74

Gene sequence:

>1026_bases
ATGACCGAGCGGAAGCGAAATCTTCGGCCAGTGCGCGACGTGGCACCGCCTACGCTGCAGTTCCGCACCGTCCACGGTTA
TCGGCGGGCATTCCGGATCGCCGGTTCCGGGCCGGCGATTCTGCTTATCCACGGGATAGGTGACAATTCCACCACCTGGA
ATGGGGTGCACGCCAAGCTCGCCCAACGATTCACCGTCATCGCTCCGGATCTACTGGGCCACGGGCAATCCGACAAGCCG
CGTGCCGACTATTCGGTTGCGGCTTACGCCAACGGCATGCGGGACCTCCTCAGCGTGCTCGACATCGAGCGGGTGACCAT
CGTGGGCCATTCGCTCGGCGGCGGGGTAGCAATGCAATTCGCCTACCAGTTCCCTCAGCTAGTCGACCGACTGATCCTGG
TCAGCGCGGGCGGTGTCACCAAGGACGTCAACATCGTCTTCCGGTTGGCCTCGTTGCCCATGGGCAGCGAGGCTATGGCC
TTGCTACGGTTGCCGCTGGTGCTGCCGGCAGTGCAAATCGCCGGGCGGATCGTGGGTAAGGCCATCGGTACCACCAGCTT
GGGGCACGACCTGCCCAATGTGCTGCGCATTTTGGACGACCTGCCAGAGCCGACGGCTTCTGCGGCGTTCGGCCGCACCC
TGCGGGCAGTGGTGGACTGGCGGGGGCAGATGGTCACCATGCTGGACCGATGCTATTTGACCGAAGCCATCCCGGTACAG
ATCATCTGGGGCACAAAGGATGTCGTGCTGCCAGTCCGTCACGCTCACATGGCGCATGCCGCCATGCCGGGCTCGCAATT
GGAGATTTTCGAGGGCTCGGGACATTTCCCGTTTCACGACGACCCTGCGCGCTTCATCGACATCGTCGAACGCTTCATGG
ACACCACTGAGCCCGCCGAATACGACCAGGCCGCGCTGCGCGCGTTGCTTCGCCGGGGTGGCGGCGAAGCAACCGTCACC
GGCTCGGCAGACACCCGTGTTGCAGTACTGAACGCCATCGGGTCCAACGAACGCAGCGCTACCTGA

Upstream 100 bases:

>100_bases
GCTCAGCAGGCCGAGAAGAAGTCCGACGACGACCCGACCTAACGCCGCGAAAGCGGCCCACAAAACGGCCCCAGTCGGCC
CGACAACAAGATTGGCGAGG

Downstream 100 bases:

>100_bases
TCACCACCGGGTCTGTTAGGGCTCTTCCCCAGGTCGTACAGTCGGGCCATGGCCATTGAGGTTTCGGTGTTGCGGGTTTT
CACCGATTCAGACGGGAATT

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKP
RADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMA
LLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVT
GSADTRVAVLNAIGSNERSAT

Sequences:

>Translated_341_residues
MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKP
RADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMA
LLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVT
GSADTRVAVLNAIGSNERSAT
>Mature_340_residues
TERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPR
ADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMAL
LRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQI
IWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVTG
SADTRVAVLNAIGSNERSAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family

Homologues:

Organism=Homo sapiens, GI218777840, Length=135, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI13376164, Length=135, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI18777795, Length=100, Percent_Identity=36, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=277, Percent_Identity=23.1046931407942, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2715_MYCTU (P0A572)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- EMBL:   X59273
- PIR:   F70532
- RefSeq:   NP_217231.1
- RefSeq:   NP_337290.1
- ProteinModelPortal:   P0A572
- EnsemblBacteria:   EBMYCT00000000612
- EnsemblBacteria:   EBMYCT00000069284
- GeneID:   887974
- GeneID:   925509
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2788
- KEGG:   mtu:Rv2715
- TIGR:   MT2788
- TubercuList:   Rv2715
- GeneTree:   EBGT00050000015213
- HOGENOM:   HBG748003
- OMA:   YRRAYRI
- ProtClustDB:   CLSK792027
- InterPro:   IPR000073
- InterPro:   IPR000639
- PRINTS:   PR00111
- PRINTS:   PR00412

Pfam domain/function: PF00561 Abhydrolase_1

EC number: NA

Molecular weight: Translated: 36933; Mature: 36802

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00120 LIPASE_SER

Important sites: ACT_SITE 111-111 ACT_SITE 247-247 ACT_SITE 275-275

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKL
CCCCCCCCCCHHHCCCCCEEEEEHHHHHHHEEECCCCCEEEEEEECCCCCCCCCHHHHHH
AQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQF
HHHHHEECHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
AYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGK
HHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
HHCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEE
IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAE
EEECCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCH
YDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSAT
HHHHHHHHHHHCCCCCEEEECCCCCEEEEEEHHCCCCCCCC
>Mature Secondary Structure 
TERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAILLIHGIGDNSTTWNGVHAKL
CCCCCCCCCHHHCCCCCEEEEEHHHHHHHEEECCCCCEEEEEEECCCCCCCCCHHHHHH
AQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMRDLLSVLDIERVTIVGHSLGGGVAMQF
HHHHHEECHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
AYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGK
HHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIGTTSLGHDLPNVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQ
HHCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEE
IIWGTKDVVLPVRHAHMAHAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDTTEPAE
EEECCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCH
YDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSAT
HHHHHHHHHHHCCCCCEEEECCCCCEEEEEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036