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The map label for this gene is suhB

Identifier: 148823891

GI number: 148823891

Start: 3027818

End: 3028690

Strand: Reverse

Name: suhB

Synonym: TBFG_12716

Alternate gene names: 148823891

Gene position: 3028690-3027818 (Counterclockwise)

Preceding gene: 148823895

Following gene: 148823889

Centisome position: 68.45

GC content: 68.27

Gene sequence:

>873_bases
GTGACACGACCTGACAACGAACCCGCGCGGCTGCGCTCTGTGGCCGAAAACCTTGCTGCCGAGGCGGCGGCCTTCGTTCG
CGGTCGTCGGGCCGAGGTTTTCGGCATCTCCAGGGCGGGCGACGGCGACGGCGCGGTGCGCGCGAAGAGCAGCCCGACCG
ATCCGGTGACCGTGGTCGACACCGACACGGAGCGGCTCTTGCGTGATCGGTTGGCTCAACTTCGGCCCGGTGACCCGATT
CTCGGGGAGGAAGGTGGTGGTCCCGCCGACGTGACGGCTACACCCTCCGACCGGGTCACTTGGGTGCTCGACCCCATCGA
CGGCACGGTGAATTTCGTCTACGGCATCCCGGCGTACGCGGTGTCGATTGGGGCACAGGTTGGCGGCATCACGGTGGCGG
GCGCGGTCGCCGACGTCGCCGCTCGCACGGTGTATTCGGCGGCGACGGGCCTCGGCGCACATCTCACCGATGAGCGGGGG
AGACATGTGTTGCGGTGCACCGGTGTCGACGAGTTGTCGATGGCGTTGCTGGGTACCGGCTTCGGGTACTCGGTTCGGTG
CCGCGAGAAGCAGGCAGAATTGCTGGCTCATGTTGTGCCGTTGGTCCGCGACGTGCGTCGGATCGGTTCTGCGGCGCTGG
ACTTGTGCATGGTAGCGGCGGGTCGGCTGGACGCCTACTACGAGCACGGGGTGCAGGTGTGGGACTGTGCGGCAGGTGCG
TTGATCGCCGCTGAGGCGGGGGCCCGCGTGTTGTTGTCAACGCCGAGAGCGGGCGGCGCGGGGTTGGTGGTGGTGGCTGC
CGCGCCCGGAATCGCCGACGAGCTGTTGGCGGCGCTACAGCGATTCAACGGCCTAGAGCCGATCCCGGACTGA

Upstream 100 bases:

>100_bases
GATGACCCTCACCTTAAACTGCGGCCCGGCAGTTGCGAGGGCGTTATGGCCGCTGGAGTCCACGCCACCATGCGGGTGGC
GACTGTGATGCGATAGGCCG

Downstream 100 bases:

>100_bases
GCCGGCCGATCAGCAGCTGTTGGCGTGGATCTTGGCCAGCAGCGCGGGATCTGAGGGCTCGGTGGCGCCGGGGCGCAGGT
TGGCAAGCACGGCGTCGATG

Product: extragenic suppressor protein suhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPI
LGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERG
RHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGA
LIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD

Sequences:

>Translated_290_residues
MTRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPI
LGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERG
RHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGA
LIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD
>Mature_289_residues
TRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPIL
GEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGR
HVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGAL
IAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI221625487, Length=216, Percent_Identity=34.2592592592593, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI5031789, Length=220, Percent_Identity=33.6363636363636, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI7657236, Length=258, Percent_Identity=34.1085271317829, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI221625507, Length=124, Percent_Identity=33.8709677419355, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788882, Length=244, Percent_Identity=34.8360655737705, Blast_Score=121, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI193202570, Length=218, Percent_Identity=34.4036697247706, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193202572, Length=216, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320493, Length=219, Percent_Identity=32.4200913242009, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6321836, Length=231, Percent_Identity=28.1385281385281, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357329, Length=284, Percent_Identity=33.4507042253521, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24664926, Length=211, Percent_Identity=35.0710900473934, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24664922, Length=241, Percent_Identity=31.9502074688797, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357303, Length=206, Percent_Identity=34.9514563106796, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24664918, Length=196, Percent_Identity=34.1836734693878, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21357957, Length=206, Percent_Identity=31.5533980582524, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_MYCBO (P65166)

Other databases:

- EMBL:   BX248343
- RefSeq:   NP_856366.1
- ProteinModelPortal:   P65166
- SMR:   P65166
- EnsemblBacteria:   EBMYCT00000016352
- GeneID:   1091891
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2720c
- GeneTree:   EBGT00050000015694
- HOGENOM:   HBG730251
- OMA:   VNFIVQK
- ProtClustDB:   CLSK792016
- BioCyc:   MBOV233413:MB2720C-MONOMER
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- PANTHER:   PTHR20854
- PRINTS:   PR00377

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 30027; Mature: 29896

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 83-83 BINDING 206-206 BINDING 235-235

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVD
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCEEEEE
TDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCEEEEECCHHHH
VSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGRHVLRCTGVDELSMALLGTG
HHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
FGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCC
LIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD
EEEECCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCEEEEE
TDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCEEEEECCHHHH
VSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGRHVLRCTGVDELSMALLGTG
HHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
FGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCC
LIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD
EEEECCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972