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The map label for this gene is hemY

Identifier: 148823867

GI number: 148823867

Start: 3004538

End: 3005896

Strand: Reverse

Name: hemY

Synonym: TBFG_12692

Alternate gene names: 148823867

Gene position: 3005896-3004538 (Counterclockwise)

Preceding gene: 148823868

Following gene: 148823866

Centisome position: 67.94

GC content: 72.33

Gene sequence:

>1359_bases
ATGACTCCCCGCTCGTATTGTGTTGTAGGAGGCGGGATTTCGGGATTGACCTCGGCGTACCGGCTGCGGCAGGCTGTCGG
CGATGACGCGACCATCACCTTGTTCGAACCGGCCGATAGGCTCGGCGGGGTATTGCGCACCGAGCATATCGGCGGACAGC
CAATGGACCTCGGCGCGGAGGCGTTCGTGCTGCGTAGGCCCGAGATGCCGGCGCTTTTGGCCGAGCTGGGCCTGTCGGAC
CGCCAACTCGCCAGCACCGGCGCGCGGCCGCTCATCTACAGCCAGCAGCGCTTGCACCCGCTGCCGCCGCAGACGGTCGT
CGGGATCCCGTCGTCGGCGGGCTCCATGGCGGGGCTGGTCGACGACGCAACCCTGGCGCGGATCGACGCCGAAGCCGCTC
GTCCGTTCACCTGGCAGGTGGGCAGCGATCCCGCGGTGGCCGACTTGGTGGCTGACCGGTTCGGCGACCAAGTCGTGGCC
CGGTCGGTGGACCCGCTGTTAAGCGGGGTATACGCGGGCTCGGCGGCGACGATCGGGCTGCGCGCGGCCGCCCCGAGCGT
GGCCGCGGCCCTGGATCGCGGGGCGACCAGTGTGACCGACGCGGTCCGGCAGGCGCTGCCGCCGGGAAGCGGCGGGCCGG
TGTTCGGCGCGCTGGACGGCGGGTATCAGGTGCTGCTCGACGGGCTCGTCCGGCGCAGCCGGGTGCACTGGGTGCGGGCC
AGGGTGGTCCAGCTCGAACGCGGCTGGGTGCTGCGCGACGAAACCGGCGGCCGCTGGCAGGCCGACGCCGTCATCCTGGC
GGTTCCGGCGCCGCGGTTGGCGCGCCTCGTCGATGGCATCGCGCCGCGCACACATGCCGCCGCCCGGCAGATCGTGAGCG
CGTCGTCGGCGGTGGTGGCGCTGGCGGTGCCCGGCGGCACCGCGTTTCCGCACTGTTCCGGCGTGCTGGTGGCCGGCGAC
GAGTCACCGCATGCCAAGGCGATCACATTGTCGTCGCGCAAATGGGGTCAGCGCGGCGACGTCGCGCTGTTGCGGCTGTC
GTTCGGTCGGTTCGGCGACGAACCGGCCCTGACGGCCTCCGACGACCAACTCCTGGCCTGGGCAGCGGACGACTTGGTCA
CGGTGTTCGGTGTGGCCGTCGACCCGGTCGACGTTCGGGTCCGGCGCTGGATCGAGGCGATGCCGCAGTACGGTCCCGGC
CATGCCGATGTGGTCGCCGAGCTGCGCGCCGGCCTGCCACCGACGCTGGCCGTTGCGGGCAGCTACCTCGACGGGATCGG
CGTGCCGGCCTGCGTCGGCGCGGCGGGCCGGGCCGTCACCAGCGTCATCGAGGCCTTAGATGCGCAGGTGGCACGATAG

Upstream 100 bases:

>100_bases
ACGCCGGTGCGGCCGGCCATATCTTCAACCTCGGCCACGGGGTGCTGCCAGAAAGCGATCCCGCGGTGCTGGCCGACCTG
GTCTCGCTCGTACACTCGCT

Downstream 100 bases:

>100_bases
ATGCCATGGCCCGTCTTGACTATGACGCGTTGAATGCGACGCTGCGCTACCTGATGTTCTCAGTGTTCTCGGTGAGTCCC
GGTGCGCTCGGTGACCAGCG

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSD
RQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVA
RSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA
RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGD
ESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPG
HADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR

Sequences:

>Translated_452_residues
MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSD
RQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVA
RSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA
RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGD
ESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPG
HADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
>Mature_451_residues
TPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSDR
QLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVAR
SVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRAR
VVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE
SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGH
ADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPOX_MYCBO (P0A5A8)

Other databases:

- EMBL:   BX248343
- RefSeq:   NP_856342.1
- ProteinModelPortal:   P0A5A8
- SMR:   P0A5A8
- EnsemblBacteria:   EBMYCT00000016904
- GeneID:   1091915
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2696c
- GeneTree:   EBGT00050000016546
- HOGENOM:   HBG450176
- OMA:   ATHDALI
- ProtClustDB:   PRK11883
- BioCyc:   MBOV233413:MB2696C-MONOMER
- BRENDA:   1.3.3.4
- GO:   GO:0005737
- InterPro:   IPR002937
- InterPro:   IPR004572
- TIGRFAMs:   TIGR00562

Pfam domain/function: PF01593 Amino_oxidase

EC number: =1.3.3.4

Molecular weight: Translated: 46847; Mature: 46716

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE
CCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCEEEECCCCCCCCCCCCC
AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV
EEEEECCCCHHHHHHCCCCCHHHHHCCCCCEEECHHHCCCCCCCCEEECCCCCCCCHHHH
DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL
CCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEE
RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA
HHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA
HHHHHHCCEEEECCCCCCEEECEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS
EEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCEECC
DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHH
SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE
CCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCEEEECCCCCCCCCCCCC
AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV
EEEEECCCCHHHHHHCCCCCHHHHHCCCCCEEECHHHCCCCCCCCEEECCCCCCCCHHHH
DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL
CCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEE
RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA
HHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA
HHHHHHCCEEEECCCCCCEEECEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS
EEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCEECC
DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHH
SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972