Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 148823787

GI number: 148823787

Start: 2936516

End: 2937550

Strand: Reverse

Name: ruvB [H]

Synonym: TBFG_12612

Alternate gene names: 148823787

Gene position: 2937550-2936516 (Counterclockwise)

Preceding gene: 148823788

Following gene: 148823783

Centisome position: 66.39

GC content: 69.86

Gene sequence:

>1035_bases
ATGACCGAGCGGTCCGACCGCGACGTTTCGCCCGCACTCACCGTCGGAGAGGGCGACATCGACGTCAGCCTGCGGCCGCG
CTCGTTACGCGAATTCATCGGCCAGCCCCGGGTCCGCGAACAGCTGCAGCTGGTCATCGAGGGAGCCAAAAACCGCGGCG
GCACACCGGATCACATTCTGCTGTCCGGTCCGCCGGGCTTGGGCAAGACGTCGTTGGCGATGATCATCGCCGCCGAGCTG
GGGTCCTCGCTGCGGGTGACGTCGGGGCCGGCGTTGGAACGCGCCGGTGACCTGGCGGCGATGCTGTCCAACCTGGTCGA
GCACGACGTGTTGTTTATCGACGAGATCCACCGCATCGCCCGGCCCGCCGAGGAGATGCTGTATCTGGCGATGGAAGACT
TCCGCGTCGATGTGGTGGTCGGCAAAGGTCCTGGGGCCACGTCGATTCCGCTGGAGGTCGCGCCGTTCACCCTGGTCGGG
GCGACTACCCGGTCGGGCGCGTTGACCGGCCCGCTGCGCGACCGGTTCGGCTTCACCGCGCACATGGATTTCTACGAGCC
CGCCGAGCTGGAGCGGGTGCTGGCCCGCTCCGCCGGAATTCTGGGTATCGAGCTGGGCGCCGACGCCGGCGCCGAAATCG
CCCGCCGTTCTCGGGGAACGCCGCGGATCGCCAACCGGTTGTTGCGCCGGGTGCGTGACTTCGCCGAGGTGCGCGCCGAC
GGCGTCATCACCCGCGACGTCGCCAAGGCCGCACTGGAGGTCTACGACGTCGACGAGCTGGGTCTGGACCGGCTGGACCG
AGCGGTGCTCTCGGCGCTGACCCGCAGCTTCGGCGGTGGTCCGGTGGGTGTGTCGACGCTGGCGGTGGCGGTCGGGGAGG
AGGCCGCCACGGTCGAGGAGGTGTGCGAACCATTTCTGGTGCGCGCGGGTATGGTCGCGCGCACCCCGCGCGGCCGGGTG
GCCACCGCCCTGGCCTGGACGCACCTGGGCATGACGCCACCGGTCGGAGCGAGTCAACCGGGGTTGTTCGAGTAG

Upstream 100 bases:

>100_bases
AACAGGCCGAGGAGGCCACCGATACGGTGCTGGCCGCCAACCATGACGCGACGACATCCAGCGCGCTGCGGTCTGCCTTG
TCGTTGCTGGGGAAGGCCCG

Downstream 100 bases:

>100_bases
TGCGCTGGAGGACCCGCTACGACGGTCCGTTCGCGCCGTTGGCGCCAAAAAGGATCCCGCCGCTGCCGCCGGTGCCGCCA
TTGACGCCGTTGCCGCCGTT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAEL
GSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVG
ATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRAD
GVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRV
ATALAWTHLGMTPPVGASQPGLFE

Sequences:

>Translated_344_residues
MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAEL
GSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVG
ATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRAD
GVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRV
ATALAWTHLGMTPPVGASQPGLFE
>Mature_343_residues
TERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELG
SSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGA
TTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRADG
VITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVA
TALAWTHLGMTPPVGASQPGLFE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=55.4545454545455, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF00004 AAA; PF05491 RuvB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 36627; Mature: 36496

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHIL
CCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
LSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIA
EECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTA
CCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHCCCEE
HMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRAD
ECCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEE
CCHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
VCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPVGASQPGLFE
HHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHIL
CCCCCCCCCCEEEECCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEE
LSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIA
EECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTA
CCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHCCCEE
HMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRAD
ECCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEE
CCHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHH
VCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPVGASQPGLFE
HHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA