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The map label for this gene is bcp

Identifier: 148823717

GI number: 148823717

Start: 2851002

End: 2851475

Strand: Direct

Name: bcp

Synonym: TBFG_12542

Alternate gene names: 148823717

Gene position: 2851002-2851475 (Clockwise)

Preceding gene: 148823715

Following gene: 148823722

Centisome position: 64.44

GC content: 62.87

Gene sequence:

>474_bases
GTGACCAAAACCACGCGTCTGACCCCCGGAGACAAAGCCCCTGCCTTCACCCTGCCCGATGCCGACGGCAACAACGTGTC
GCTGGCCGACTACCGAGGACGCCGCGTCATCGTGTACTTCTACCCGGCGGCCTCGACACCGGGATGCACCAAGCAGGCTT
GTGATTTTCGCGACAATCTGGGCGATTTCACCACTGCCGGCCTCAACGTCGTCGGTATCTCCCCCGACAAGCCGGAGAAG
CTCGCTACGTTCCGCGATGCCCAGGGCCTGACGTTTCCGCTGCTGTCTGATCCCGACCGCGAGGTGTTGACGGCCTGGGG
TGCCTACGGGGAGAAGCAGATGTATGGCAAGACGGTGCAGGGGGTGATCCGGTCCACCTTCGTCGTCGATGAAGACGGAA
AGATCGTCGTCGCGCAGTACAACGTCAAGGCCACCGGCCACGTCGCTAAGCTTCGGCGCGACCTGTCGGTATAG

Upstream 100 bases:

>100_bases
TGCTTGATGGTATTGGGATCGCGGTCCACCACGTGCTGTCCTCCAAGTTCTCCAGTCGCCCACTGCCGGCCTGCGTCGCC
CGCCGAACTACCCTAGATCA

Downstream 100 bases:

>100_bases
CCGCGAGCTTGGCCAGCAGCAGCGCTTCGGCGGTCGCCGCGCGTTCCAGCACACCCAGATGCAGGCTTTCATTGACACTG
TGCGCCTGCGTTCCGGGGTC

Product: bacterioferritin comigratory protein bcp

Products: NA

Alternate protein names: Bacterioferritin comigratory protein; Thioredoxin reductase

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTKTTRLTPGDKAPAFTLPDADGNNVSLADYRGRRVIVYFYPAASTPGCTKQACDFRDNLGDFTTAGLNVVGISPDKPEK
LATFRDAQGLTFPLLSDPDREVLTAWGAYGEKQMYGKTVQGVIRSTFVVDEDGKIVVAQYNVKATGHVAKLRRDLSV

Sequences:

>Translated_157_residues
MTKTTRLTPGDKAPAFTLPDADGNNVSLADYRGRRVIVYFYPAASTPGCTKQACDFRDNLGDFTTAGLNVVGISPDKPEK
LATFRDAQGLTFPLLSDPDREVLTAWGAYGEKQMYGKTVQGVIRSTFVVDEDGKIVVAQYNVKATGHVAKLRRDLSV
>Mature_156_residues
TKTTRLTPGDKAPAFTLPDADGNNVSLADYRGRRVIVYFYPAASTPGCTKQACDFRDNLGDFTTAGLNVVGISPDKPEKL
ATFRDAQGLTFPLLSDPDREVLTAWGAYGEKQMYGKTVQGVIRSTFVVDEDGKIVVAQYNVKATGHVAKLRRDLSV

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788825, Length=141, Percent_Identity=51.063829787234, Blast_Score=155, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322180, Length=134, Percent_Identity=40.2985074626866, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): BCP_MYCTU (O53226)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842580
- PIR:   F70870
- RefSeq:   NP_217037.1
- RefSeq:   NP_337090.1
- ProteinModelPortal:   O53226
- EnsemblBacteria:   EBMYCT00000000912
- EnsemblBacteria:   EBMYCT00000070277
- GeneID:   887694
- GeneID:   925722
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2597
- KEGG:   mtu:Rv2521
- TIGR:   MT2597
- TubercuList:   Rv2521
- GeneTree:   EBGT00050000015906
- HOGENOM:   HBG493509
- OMA:   LRDNMDD
- ProtClustDB:   CLSK791902
- GO:   GO:0005829
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: =1.11.1.15

Molecular weight: Translated: 17077; Mature: 16946

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: ACT_SITE 49-49

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTTRLTPGDKAPAFTLPDADGNNVSLADYRGRRVIVYFYPAASTPGCTKQACDFRDNL
CCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHCHHHCC
GDFTTAGLNVVGISPDKPEKLATFRDAQGLTFPLLSDPDREVLTAWGAYGEKQMYGKTVQ
CCEECCCEEEEEECCCCCHHHHEECCCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
GVIRSTFVVDEDGKIVVAQYNVKATGHVAKLRRDLSV
HHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TKTTRLTPGDKAPAFTLPDADGNNVSLADYRGRRVIVYFYPAASTPGCTKQACDFRDNL
CCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHCHHHCC
GDFTTAGLNVVGISPDKPEKLATFRDAQGLTFPLLSDPDREVLTAWGAYGEKQMYGKTVQ
CCEECCCEEEEEECCCCCHHHHEECCCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHHHH
GVIRSTFVVDEDGKIVVAQYNVKATGHVAKLRRDLSV
HHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036