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The map label for this gene is yjjK [C]

Identifier: 148823676

GI number: 148823676

Start: 2797040

End: 2798716

Strand: Reverse

Name: yjjK [C]

Synonym: TBFG_12501

Alternate gene names: 148823676

Gene position: 2798716-2797040 (Counterclockwise)

Preceding gene: 148823677

Following gene: 148823675

Centisome position: 63.26

GC content: 62.73

Gene sequence:

>1677_bases
ATGGCTGAGTTCATCTACACGATGAAGAAGGTCCGCAAGGCGCACGGCGATAAGGTGATCCTCGACGACGTGACGTTGAG
TTTCTATCCGGGCGCCAAGATCGGTGTCGTCGGCCCCAACGGGGCCGGTAAGTCGAGCGTCTTGCGGATCATGGCCGGTT
TGGACAAGCCGAACAACGGCGATGCCTTCCTGGCCACCGGCGCCACCGTGGGCATCCTGCAACAGGAACCGCCGCTGAAC
GAGGACAAGACCGTTCGCGGCAATGTGGAAGAGGGCATGGGGGACATCAAGATCAAGCTCGACCGCTTCAACGAGGTCGC
CGAATTGATGGCCACCGACTACACCGACGAGCTGATGGAAGAGATGGGTCGGCTGCAAGAGGAACTGGACCACGCCGACG
CGTGGGACCTCGACGCGCAGCTCGAGCAGGCCATGGATGCGCTGCGCTGTCCGCCGGCCGACGAGCCGGTAACCAACCTA
TCCGGTGGCGAGCGTCGCCGGGTGGCGCTGTGCAAACTGCTGTTGTCCAAACCCGACCTGTTGTTGCTCGACGAGCCGAC
CAACCACCTAGACGCGGAAAGTGTGCAGTGGCTCGAACAGCATCTGGCCAGCTACCCCGGTGCGATCCTGGCGGTCACCC
ACGACCGTTACTTCCTGGACAACGTCGCGGAATGGATCCTGGAGCTCGATCGTGGCCGCGCCTACCCCTATGAGGGCAAC
TACTCGACCTATCTGGAGAAAAAAGCCGAGCGGCTCGCGGTGCAAGGCCGCAAGGACGCGAAGCTGCAAAAGCGGTTGAC
CGAGGAGTTGGCTTGGGTCCGGTCCGGGGCCAAGGCGCGCCAGGCCAAAAGCAAGGCGCGCCTGCAGCGCTACGAGGAGA
TGGCAGCCGAGGCGGAGAAGACCCGCAAGCTCGACTTCGAGGAGATTCAGATCCCGGTCGGGCCCCGCCTAGGCAACGTG
GTGGTTGAGGTCGACCACCTCGATAAGGGCTACGACGGGCGCGCCCTGATCAAGGACCTGTCGTTCAGCTTGCCCCGCAA
TGGCATCGTCGGCGTCATTGGGCCCAACGGGGTAGGCAAGACCACACTGTTCAAAACCATCGTCGGGCTCGAGACACCGG
ACAGCGGCAGCGTCAAGGTCGGCGAGACCGTCAAGCTGAGTTACGTGGACCAGGCCCGTGCTGGCATCGATCCGCGGAAG
ACCGTCTGGGAGGTTGTCTCGGACGGTCTGGACTATATCCAGGTCGGTCAAACCGAAGTGCCGTCACGGGCCTACGTGTC
GGCATTCGGGTTTAAGGGACCGGACCAGCAAAAACCGGCCGGTGTGCTATCCGGCGGGGAGCGCAACAGGCTCAACCTTG
CGTTGACGCTCAAACAGGGCGGCAACCTGATTCTGCTCGACGAACCGACGAACGACCTGGATGTCGAGACTCTGGGTTCG
CTGGAGAATGCTCTGCTGAACTTCCCCGGCTGCGCCGTGGTGATTTCGCACGATCGCTGGTTTCTTGACCGCACGTGCAC
GCACATCCTGGCGTGGGAGGGTGACGACGACAACGAGGCGAAGTGGTTCTGGTTCGAGGGCAACTTCGGCGCCTACGAGG
AGAACAAGGTGGAACGGCTCGGTGTCGACGCCGCTCGACCGCATAGGGTCACCCACCGCAAGCTGACGCGCGGCTAA

Upstream 100 bases:

>100_bases
CCCTGCCCATATCGGCTTAGGGGTCGCCTCGATGCTGCCCCGGCGGTGCCTAGGATGGTTCGCGAGGTAACCCGAAGGAC
CAGAAAGGCAACACCGCGGC

Downstream 100 bases:

>100_bases
TGTTAGCTTCGCCCACGCCCCGTGACGATGCGTCCGGAACGCCGCACCCAGGAGCGGGAAAATTGAATCGAGCGGTACCC
GTCGTGAGTTGGGAGCAATC

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMAGLDKPNNGDAFLATGATVGILQQEPPLN
EDKTVRGNVEEGMGDIKIKLDRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRCPPADEPVTNL
SGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGN
YSTYLEKKAERLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEKTRKLDFEEIQIPVGPRLGNV
VVEVDHLDKGYDGRALIKDLSFSLPRNGIVGVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGS
LENALLNFPGCAVVISHDRWFLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRVTHRKLTRG

Sequences:

>Translated_558_residues
MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMAGLDKPNNGDAFLATGATVGILQQEPPLN
EDKTVRGNVEEGMGDIKIKLDRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRCPPADEPVTNL
SGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGN
YSTYLEKKAERLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEKTRKLDFEEIQIPVGPRLGNV
VVEVDHLDKGYDGRALIKDLSFSLPRNGIVGVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGS
LENALLNFPGCAVVISHDRWFLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRVTHRKLTRG
>Mature_557_residues
AEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMAGLDKPNNGDAFLATGATVGILQQEPPLNE
DKTVRGNVEEGMGDIKIKLDRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRCPPADEPVTNLS
GGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNY
STYLEKKAERLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEKTRKLDFEEIQIPVGPRLGNVV
VEVDHLDKGYDGRALIKDLSFSLPRNGIVGVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRKT
VWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGSL
ENALLNFPGCAVVISHDRWFLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRVTHRKLTRG

Specific function: Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI148612853, Length=517, Percent_Identity=30.3675048355899, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI10947137, Length=556, Percent_Identity=27.8776978417266, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI27881506, Length=552, Percent_Identity=27.8985507246377, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI10947135, Length=572, Percent_Identity=28.4965034965035, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI69354671, Length=572, Percent_Identity=28.6713286713287, Blast_Score=172, Evalue=7e-43,
Organism=Escherichia coli, GI2367384, Length=561, Percent_Identity=56.6844919786096, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1787182, Length=502, Percent_Identity=36.6533864541833, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1787041, Length=513, Percent_Identity=31.7738791423002, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1789751, Length=543, Percent_Identity=30.7550644567219, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI48994943, Length=490, Percent_Identity=23.8775510204082, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788225, Length=204, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081791, Length=170, Percent_Identity=30.5882352941176, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789891, Length=228, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787370, Length=181, Percent_Identity=28.7292817679558, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788165, Length=185, Percent_Identity=30.8108108108108, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI48994883, Length=234, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788761, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=180, Percent_Identity=29.4444444444444, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=172, Percent_Identity=27.3255813953488, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081782, Length=208, Percent_Identity=29.3269230769231, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081834, Length=222, Percent_Identity=28.8288288288288, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=553, Percent_Identity=28.9330922242315, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17555318, Length=537, Percent_Identity=27.0018621973929, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17553372, Length=513, Percent_Identity=31.1890838206628, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI115534520, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=226, Percent_Identity=29.646017699115, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=209, Percent_Identity=25.8373205741627, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=509, Percent_Identity=29.2730844793713, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321121, Length=540, Percent_Identity=27.962962962963, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6323278, Length=388, Percent_Identity=27.0618556701031, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=386, Percent_Identity=26.4248704663212, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=26.5625, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=29.5938104448743, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24642252, Length=519, Percent_Identity=28.5163776493256, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI18859989, Length=519, Percent_Identity=28.5163776493256, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24641342, Length=596, Percent_Identity=27.6845637583893, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24648314, Length=165, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2477_MYCTU (O53204)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   D70867
- RefSeq:   NP_216993.1
- RefSeq:   NP_337040.1
- HSSP:   P58301
- ProteinModelPortal:   O53204
- SMR:   O53204
- EnsemblBacteria:   EBMYCT00000003609
- EnsemblBacteria:   EBMYCT00000070076
- GeneID:   887757
- GeneID:   925776
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2552
- KEGG:   mtu:Rv2477c
- TIGR:   MT2552
- TubercuList:   Rv2477c
- GeneTree:   EBGT00050000015051
- HOGENOM:   HBG758042
- OMA:   KWYWFEG
- ProtClustDB:   PRK11819
- GO:   GO:0005829
- GO:   GO:0009295
- GO:   GO:0040007
- GO:   GO:0006810
- InterPro:   IPR022374
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406
- Gene3D:   G3DSA:3.40.1140.10
- SMART:   SM00382
- TIGRFAMs:   TIGR03719

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 61894; Mature: 61763

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMAGLDKPNNG
CCHHHHHHHHHHHHCCCEEEEECEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCC
DAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKLDRFNEVAELMATDYTDELME
CEEEECCCEEEEEECCCCCCCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHCCCHHHHHH
EMGRLQEELDHADAWDLDAQLEQAMDALRCPPADEPVTNLSGGERRRVALCKLLLSKPDL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
LLLDEPTNHLDAESVQWLEQHLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGN
EEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
YSTYLEKKAERLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIVGVIGPNGVGK
HHCCCHHHEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCH
TTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRKTVWEVVSDGLDYIQVGQTEV
HHHHHHHHCCCCCCCCCEEECCEEEEEEHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCC
PSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGS
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHH
LENALLNFPGCAVVISHDRWFLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERL
HHHHHHCCCCEEEEEECCCEEHHHHEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHH
GVDAARPHRVTHRKLTRG
CCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIMAGLDKPNNG
CHHHHHHHHHHHHCCCEEEEECEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCC
DAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKLDRFNEVAELMATDYTDELME
CEEEECCCEEEEEECCCCCCCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHCCCHHHHHH
EMGRLQEELDHADAWDLDAQLEQAMDALRCPPADEPVTNLSGGERRRVALCKLLLSKPDL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
LLLDEPTNHLDAESVQWLEQHLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGN
EEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
YSTYLEKKAERLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIVGVIGPNGVGK
HHCCCHHHEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCH
TTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRKTVWEVVSDGLDYIQVGQTEV
HHHHHHHHCCCCCCCCCEEECCEEEEEEHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCC
PSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGS
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHH
LENALLNFPGCAVVISHDRWFLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERL
HHHHHHCCCCEEEEEECCCEEHHHHEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHH
GVDAARPHRVTHRKLTRG
CCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036