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The map label for this gene is malL [H]

Identifier: 148823671

GI number: 148823671

Start: 2788238

End: 2789878

Strand: Direct

Name: malL [H]

Synonym: TBFG_12496

Alternate gene names: 148823671

Gene position: 2788238-2789878 (Clockwise)

Preceding gene: 148823670

Following gene: 148823672

Centisome position: 63.02

GC content: 67.28

Gene sequence:

>1641_bases
ATGGACCAACACCAGCGACCGGATCCAATGGGCCCCGGCTCTCCTCGCGCCAGCGCTCGTCGACCGGAGCCAGATCCGAT
GGGCGAGCCGTGGTGGTCGCGAGCCGTGTTCTACCAGGTCTATCCCCGATCGTTCGCCGACAGCAACGGCGACGGGGTGG
GCGACCTGGACGGGTTGGCGAGCCGGCTTGACCACCTGCAACAGCTCGGTGTCGACGCGATCTGGATCAACCCGGTCACC
GTCTCGCCGATGGCAGACCACGGATACGACGTCGCCGATCCCCGCGACATCGACCCACTCTTCGGCGGGATGCCGGCGTT
CGAACGGTTGGTCGCTGCGGCACACCGGCAGGGCATCAAAGTCACCATGGACGTGGTGCCCAACCACACCAGTTCGGCGC
ACCCATGGTTTCAGGCCGCGCTGGCTGACCTCCCGGGTAGCCCGGCGCGGGATCGCTATTTCTTTCGCGACGGGCGGGGC
CCCGACGGGTCGCTGCCGCCGAACAACTGGGAGTCGGTGTTCGGCGGGCCGGCCTGGACCCGAGTGCGCGAACCGGACGG
CAACCCGGGCCAGTGGTACCTGCACCTTTTCGACACCGAACAGCCGGACCTGAACTGGGACAACCCGGAAATCCTTGACG
ACTTCGAGAAAACACTGCGCTTCTGGCTGGACCGCGGCGTGGATGGCTTCCGCATCGACGTGGCGCACGGCATGGCCAAG
CCCCCGGGCCTGCCGGACTCACCGGACCTGGGCATCGAGGTGCTGCACCACCGCGATGACGACCCGCGCTTCAACCACCC
GAATGTGCACGCGATTCACCGCGACATCCGCACGGTGATCGACGAGTACCCCGGAGCGGTAACCGTCGGCGAGGTGTGGG
TACACGACAACGCCCGCTGGGCGGAGTATCTGCGGCCCGACGAACTGCATCTCGGCTTCAATTTCCGGCTGGCGCGAACC
GAGTTCGACGCCGCCGAGATCCGCGACGCGGTGGCGAACTCCCTGGCCGCCGCGGCGCTGCAGAACGCGACCCCAACCTG
GACGCTGGCCAATCACGATGTGGGACGGGAGGTTAGCCGCTACGGCGGCGGCGAGATCGGGCTGCGCCGGGCCAAGGCGA
TGGCGGTGGTGATGCTCGCCCTGCCGGGCGTGGTCTTCCTCTACAACGGCCAGGAACTGGGTTTGCCCGACGTGGACCTG
CCCGACGAGGTGCTGCAGGATCCGACGTGGGAACGCTCGGGACGCACCGAACGCGGTCGCGATGGCTGCCGGGTGCCGAT
TCCCTGGTCGGGCAACATTCCCCCGTTCGGGTTCTCGACGTGTCCAGACACCTGGTTGCCGATGCCGCCGGAATGGGCGG
CGCTGACCGCCGAAAAACAACGCGCTGATGCCGGCTCGACCTTGTCGTTTTTTCGACTTGCACTCAGATTACGTAGGGAA
CGAAATGAATTCGACGGCGACGTCGACTGGCTGGCCGCGCCCGACGATGCGCTGATATTCCGGCGTCACGGCGGGGGTTT
GGTGTGCGCGCTCAACGCCGCTGAGCGTCCGCTGGCGCTGCCGGCAGGTGAACCCATCCTGGCCAGCGCACCGTTGACCG
ACGCCACGTTGCCACCCAATGCCGCGGCCTGGCTGGTGTAG

Upstream 100 bases:

>100_bases
TGGCCTCCATCGACTCAGAAACGCTCGATGACGAGCACCGTCGAGAGTTGCTGGATTATCTGGAGATGGCCGCTCACTCG
CTGGTCAACTCCCCGTTTTG

Downstream 100 bases:

>100_bases
CGGCATTCCGAGCTATGCCTGCCCGACATATAAGCGCATACGCATCCTAGGCGGGCACCGTCTAGGTATGATGATGCGGA
TCGCCGTGCGGCTACCCGGG

Product: alpha-glucosidase aglA (maltase)

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLASRLDHLQQLGVDAIWINPVT
VSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRG
PDGSLPPNNWESVFGGPAWTRVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARWAEYLRPDELHLGFNFRLART
EFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDL
PDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRE
RNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPNAAAWLV

Sequences:

>Translated_546_residues
MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLASRLDHLQQLGVDAIWINPVT
VSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRG
PDGSLPPNNWESVFGGPAWTRVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARWAEYLRPDELHLGFNFRLART
EFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDL
PDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRE
RNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPNAAAWLV
>Mature_546_residues
MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLASRLDHLQQLGVDAIWINPVT
VSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRG
PDGSLPPNNWESVFGGPAWTRVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARWAEYLRPDELHLGFNFRLART
EFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDL
PDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRE
RNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPNAAAWLV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=469, Percent_Identity=30.7036247334755, Blast_Score=225, Evalue=7e-59,
Organism=Escherichia coli, GI1790687, Length=480, Percent_Identity=36.6666666666667, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1786604, Length=577, Percent_Identity=23.050259965338, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32565753, Length=560, Percent_Identity=23.5714285714286, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=530, Percent_Identity=24.9056603773585, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322245, Length=499, Percent_Identity=34.2685370741483, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6319776, Length=576, Percent_Identity=31.9444444444444, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6321726, Length=508, Percent_Identity=33.6614173228346, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321731, Length=576, Percent_Identity=31.7708333333333, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322241, Length=508, Percent_Identity=33.6614173228346, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6322021, Length=508, Percent_Identity=33.6614173228346, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6324416, Length=508, Percent_Identity=33.6614173228346, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24583749, Length=483, Percent_Identity=36.4389233954451, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24583747, Length=483, Percent_Identity=36.4389233954451, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI221330053, Length=553, Percent_Identity=32.9113924050633, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24586599, Length=538, Percent_Identity=32.3420074349442, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24586589, Length=507, Percent_Identity=35.5029585798817, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24586597, Length=512, Percent_Identity=33.0078125, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24583745, Length=483, Percent_Identity=33.7474120082816, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24586591, Length=506, Percent_Identity=32.2134387351779, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586587, Length=469, Percent_Identity=31.9829424307036, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI45549022, Length=545, Percent_Identity=30.4587155963303, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24586593, Length=508, Percent_Identity=32.8740157480315, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI281360393, Length=455, Percent_Identity=29.4505494505495, Blast_Score=165, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 60444; Mature: 60444

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCHHHCCCCCCCCCCHHHHH
SRLDHLQQLGVDAIWINPVTVSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIK
HHHHHHHHCCCCEEEECCEEECCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCE
VTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRGPDGSLPPNNWESVFGGPAWT
EEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCC
RVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
EEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCC
PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARW
CCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHH
AEYLRPDELHLGFNFRLARTEFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSR
HHHCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHH
YGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDLPDEVLQDPTWERSGRTERGR
HCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
DGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRE
CCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPN
HHHCCCCCEEEECCCCEEEEEECCCCEEEEECCCCCCEECCCCCCEEECCCCCCCCCCCC
AAAWLV
CCCCCC
>Mature Secondary Structure
MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCHHHCCCCCCCCCCHHHHH
SRLDHLQQLGVDAIWINPVTVSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIK
HHHHHHHHCCCCEEEECCEEECCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCE
VTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRGPDGSLPPNNWESVFGGPAWT
EEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCC
RVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
EEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCC
PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARW
CCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHH
AEYLRPDELHLGFNFRLARTEFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSR
HHHCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHH
YGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDLPDEVLQDPTWERSGRTERGR
HCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
DGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRE
CCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPN
HHHCCCCCEEEECCCCEEEEEECCCCEEEEECCCCCCEECCCCCCEEECCCCCCCCCCCC
AAAWLV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]