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The map label for this gene is hrcA [H]

Identifier: 148823576

GI number: 148823576

Start: 2667357

End: 2668388

Strand: Reverse

Name: hrcA [H]

Synonym: TBFG_12399

Alternate gene names: 148823576

Gene position: 2668388-2667357 (Counterclockwise)

Preceding gene: 148823578

Following gene: 148823575

Centisome position: 60.31

GC content: 63.95

Gene sequence:

>1032_bases
ATGGGAAGCGCCGACGAGCGTCGCTTTGAGGTGCTGCGTGCCATCGTCGCCGACTTCGTTGCAACCCAGGAACCGATCGG
CTCCAAATCCCTGGTGGAACGCCATAACCTGGGAGTCTCGTCGGCCACAGTCCGCAATGACATGGCGGTGCTGGAAGCCG
AAGGCTATATCACTCAGCCACACACCAGTTCCGGACGCGTGCCCACGGAGAAGGGCTACCGCGAGTTCGTCGACCGGCTC
GAGGACGTCAAACCCCTATCGTCGGCCGAGCGCCGGGCGATCCAGAGCTTCCTTGAATCCGGTGTCGATCTCGACGACGT
GCTGCGCCGTGCCGTGCGATTGCTGGCGCAGCTGACCCGCCAGGTGGCCGTCGTGCAGTACCCGACGTTGTCAACGTCGA
CCGTTCGCCACTTGGAGGTGATCGCGCTGACACCGGCCCGGCTGCTGATGATGGTCATCACCGACTCCGGCCGGGTTGAT
CAGCGCATCGTCGAACTCGGCGATGTCATCGACGATCACCAGCTAGCCCAGCTGCGTGAAATACTCGGCCAGGCGCTGGA
AGGCAAGAAGCTTTCAGCGGCTTCGGTGGCGGTCGCCGACCTCGCCAGCCAGCTGGGCGGCGCCGGCGGATTGGGCGACG
CCGTGGGCCGCGCGGCGACCGTATTGCTGGAGTCGCTAGTGGAGCACACCGAGGAACGCCTTTTGCTGGGCGGTACCGCC
AATCTAACCCGCAACGCTGCGGACTTCGGTGGTTCACTGCGGTCAATATTGGAAGCACTTGAGGAGCAGGTGGTGGTGTT
GCGGCTGCTGGCGGCTCAGCAGGAAGCCGGCAAGGTGACGGTTCGCATAGGTCATGAGACGGCGTCTGAGCAGATGGTGG
GCACCTCGATGGTGTCGACGGCCTACGGTACCGCCCATACCGTCTACGGCGGTATGGGTGTGGTGGGCCCCACCCGGATG
GACTATCCGGGAACTATCGCCAGCGTGGCTGCGGTTGCTCTTTATATCGGCGACGTCCTGGGTGCTCGATGA

Upstream 100 bases:

>100_bases
CCCCTGACCATCGGCAGACGCCTGCTAGATGACGGTCAGTGGCCGCCGAGAACGTAAAATGAAGCCGGTCAGGCAGCGTA
AGAAGTGAGGTGAGCAGTCG

Downstream 100 bases:

>100_bases
ACGCGCACCTGCTGCAGGGTTTGTGGATAGCCGCTTGAGAAGCGGCATAAAGACGCGGCATAGGAGAATCAAGCGTGGCA
CGCGATTATTACGGGCTGCT

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRL
EDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMMVITDSGRVD
QRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRM
DYPGTIASVAAVALYIGDVLGAR

Sequences:

>Translated_343_residues
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRL
EDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMMVITDSGRVD
QRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRM
DYPGTIASVAAVALYIGDVLGAR
>Mature_342_residues
GSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLE
DVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMMVITDSGRVDQ
RIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTAN
LTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMD
YPGTIASVAAVALYIGDVLGAR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 36507; Mature: 36376

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAVVQYPTLSTSTVRHLEVIALTPARLLMMVITDSGRVDQRIVELGDVIDDHQLAQLRE
HHHHHCCCCCCHHHHHHHHHEEECHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHH
ILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVST
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
AYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
HHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQP
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCHHEEECCCCEECC
HTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTR
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QVAVVQYPTLSTSTVRHLEVIALTPARLLMMVITDSGRVDQRIVELGDVIDDHQLAQLRE
HHHHHCCCCCCHHHHHHHHHEEECHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHH
ILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
NLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVST
HHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
AYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
HHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA