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The map label for this gene is 148823547

Identifier: 148823547

GI number: 148823547

Start: 2636685

End: 2636969

Strand: Reverse

Name: 148823547

Synonym: TBFG_12370

Alternate gene names: NA

Gene position: 2636969-2636685 (Counterclockwise)

Preceding gene: 148823548

Following gene: 148823545

Centisome position: 59.6

GC content: 63.16

Gene sequence:

>285_bases
ATGACCATCAACTATCAGTTCGGTGATGTCGACGCTCATGGCGCCATGATCCGCGCTCAGGCCGGGTTGCTGGAGGCGGA
GCATCAGGCCATCGTTCGTGATGTGTTGGCCGCGGGTGACTTTTGGGGCGGCGCCGGTTCGGTGGCTTGCCAGGAGTTCA
TCACCCAGCTGGGCCGTAACTTCCAGGTGATCTACGAGCAGGCCAACGCCCACGGGCAGAAGGTGCAGGCTGCCGGCAAC
AACATGGCACAAACCGACAGCGCCGTCGGCTCCAGCTGGGCCTGA

Upstream 100 bases:

>100_bases
ACAACTACGAGCAGCAAGAGCAGGCCTCCCAGCAGATCCTCAGCAGCTAACGTCAGCCGCTGCAGCACAATACTTTTACA
AGCGAAGGAGAACAGGTTCG

Downstream 100 bases:

>100_bases
CAGGGTCGACGAACCCTAGGAAGAAGCCTAGGTCGACGGCCACACGCGCCAGCGTACGGGTATCCCCGTGCGCTGGCGCG
TGGCTTAGAACCGCCCGCCG

Product: Esat-6 like protein esxO (Esat-6 like protein 6)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGN
NMAQTDSAVGSSWA

Sequences:

>Translated_94_residues
MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGN
NMAQTDSAVGSSWA
>Mature_93_residues
TINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGNN
MAQTDSAVGSSWA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ES6L6_MYCTU (P95242)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   C70662
- RefSeq:   NP_216862.1
- RefSeq:   NP_336890.1
- PDB:   3OGI
- PDBsum:   3OGI
- EnsemblBacteria:   EBMYCT00000003937
- EnsemblBacteria:   EBMYCT00000069038
- GeneID:   888956
- GeneID:   926392
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2411
- KEGG:   mtu:Rv2346c
- TIGR:   MT2411
- TubercuList:   Rv2346c
- GeneTree:   EBGT00050000017993
- HOGENOM:   HBG569450
- OMA:   ACQEFIS
- ProtClustDB:   CLSK790909
- InterPro:   IPR009416
- InterPro:   IPR010310
- PIRSF:   PIRSF037656

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 9954; Mature: 9823

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRN
CEECCCCCCCCCCCCEEHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
FQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
CEEEHHHHCCCCCEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRN
EECCCCCCCCCCCCEEHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
FQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
CEEEHHHHCCCCCEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036