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The map label for this gene is 148823519

Identifier: 148823519

GI number: 148823519

Start: 2602636

End: 2603514

Strand: Reverse

Name: 148823519

Synonym: TBFG_12342

Alternate gene names: NA

Gene position: 2603514-2602636 (Counterclockwise)

Preceding gene: 148823520

Following gene: 148823515

Centisome position: 58.84

GC content: 66.67

Gene sequence:

>879_bases
GTGACCATCGTCGTCGGGTATTTGGCTGGCAAGGTCGGTCCGTCCGCATTACATCTAGCCGTCCGCGTCGCGCGGATGCA
CAAGACGTCGCTCACAGTGGCCACCATCGTGCGCAGGCACTGGCCGACACCGTCGCTCGCCCGCGTCGACGCCGAGTACG
AGCTCTGGTCTGAGCAGCTGGCTGCCGCCTCCGCGCGAGAGGCCCAGCGCTACCTGCGCAGACTGGCCGACGGGATCGAG
GTCAGCTACCACCACCGCGCACACCGATCGGTGTCGGCTGGTCTGCTCGACGTCGTCGAGGAACTCGAAGCCGAGGTGCT
GGTGCTGGGGTCGTTTCCCAGCGGGCGGCGCGCGCGGGTGTTGATCGGCTCGACCGCCGACCGGCTGCTGCATTCGTCGC
CGGTACCGGTGGCGATCACCCCCCGCCGCTACCGTTGCTACACCGACCGGTTGACACGGCTCAGCTGCGGCTACTCCGCG
ACGTCGGGTTCGGTCGACGTGGTGAGGCGATGCGGCCACCTGGCCAGCCGGTATGGCGTGCCGATGCGGGTGATCACATT
CGCGGTCCGCGGCCGGACCATGTATCCGCCCGAAGTGGGGCTGCATGCCGAGGCTTCGGTTCTGGAGGCATGGGCGGCGC
AAGCGCGAGAACTGTTGGAAAAACTAAGAATTAACGGCGTCGTGAGTGAAGACGTTGTGCTGCAAGTGGTCACCGGGAAC
GGCTGGGCGCAGGCGCTGGACGCTGCGGACTGGCAGGACGGGGAGATCCTGGCCTTGGGCACCTCGCCGTTCGGTGATGT
CGCGAGAGTATTCCTCGGCTCCTGGAGTGGCAAGATCATTCGCTACAGCCCGGTCCCCGTGCTAGTACTACCGGGCTAG

Upstream 100 bases:

>100_bases
ACTGGTACACCTGGCTGGCGTTCAGCGGATGGGTGGCGGTGGCAGTGATCTTTTACCTGATGTGGGGTCGGCACCACAGT
GCGCTCAACGAGGAAGTGCC

Downstream 100 bases:

>100_bases
ATCGCAACTAGCGCTGTGTGGCAGCATTGGCCGCCGCCTGTGCCTGCCTCAGGGTTGTCGTGACATCGCCACGGCCGAGG
AACATTTCGTCGAAGTAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: USP Rv2319c

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLADGIE
VSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSA
TSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGN
GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG

Sequences:

>Translated_292_residues
MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLADGIE
VSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSA
TSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGN
GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG
>Mature_291_residues
TIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLADGIEV
SYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSAT
SGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGNG
WAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG

Specific function: Unknown

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2319_MYCTU (P64995)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   H70703
- RefSeq:   NP_216835.1
- RefSeq:   NP_336861.1
- ProteinModelPortal:   P64995
- EnsemblBacteria:   EBMYCT00000003710
- EnsemblBacteria:   EBMYCT00000071730
- GeneID:   885171
- GeneID:   924030
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2382
- KEGG:   mtu:Rv2319c
- TIGR:   MT2382
- TubercuList:   Rv2319c
- GeneTree:   EBGT00050000015434
- HOGENOM:   HBG509996
- OMA:   WKKGDLL
- ProtClustDB:   CLSK872049
- GO:   GO:0040007
- InterPro:   IPR014729
- InterPro:   IPR006015
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01438

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 31867; Mature: 31736

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQL
CEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHH
AAASAREAQRYLRRLADGIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARV
HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
LIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGV
EECCCHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
PMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGN
CHHHEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG
CHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEECC
>Mature Secondary Structure 
TIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQL
EEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHH
AAASAREAQRYLRRLADGIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARV
HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
LIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGV
EECCCHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
PMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGN
CHHHEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG
CHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036