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The map label for this gene is 148823504

Identifier: 148823504

GI number: 148823504

Start: 2586597

End: 2587886

Strand: Direct

Name: 148823504

Synonym: TBFG_12327

Alternate gene names: NA

Gene position: 2586597-2587886 (Clockwise)

Preceding gene: 148823502

Following gene: 148823509

Centisome position: 58.46

GC content: 67.44

Gene sequence:

>1290_bases
ATGACCCAAACGCTGCGCCTTACCGCGCTGGACGAGATGTTCATCACCGATGACATTGACATCGTTCCTTCGGTGCAGAT
CGAGGCGCGGGTGTCCGGTCGTTTCGACCTCGACCGGCTTGCCGCTGCCCTGCGCGCCGCCGTCGCCAAGCACGCCCTGG
CTCGGGCGCGGCTTGGCCGCGCCAGCCTAACCGCACGGACGCTGTATTGGGAGGTACCCGACCGCGCGGATCACCTCGCC
GTGGAGATCACCGATGAACCCGTCGGTGAAGTTCGCAGTCGCTTTTATGCGCGGGCTCCCGAACTGCACCGAAGCCCGGT
CTTTGCCGTCGCGGTGGTACGCGAGACCGTGGGCGACCGCCTCCTGCTCAACTTCCACCACGCGGCCTTCGACGGCATGG
GCGGGCTGCGTCTGTTGCTCTCACTGGCCCGGGCCTATGCGGGCGAGCCTGACGAGGTCGGTGGCCCTCCGATCGAGGAA
GCCCGCAACCTTAAAGGCGTCGCCGGCTCCCGCGACCTGTTCGACGTCCTGATCCGCGCCCGCGGCCTGGCAAAACCGGC
CATCGACCGGAAGCGGACCACCCGGGTCGCCCCGGATGGCGGCTCGCCCGACGGGCCGCGCTTCGTGTTCGCCCCACTCA
CCATCGAGAGCGACGAGATGGCAACCGCGGTTGCTCGTCGACCCGAGGGGGCGACGGTGAACGACCTGGCGATGGCCGCG
CTGGCGTTGACGATCCTGCAGTGGAACCGCACACACGATGTCCCAGCCGCCGATTCCGTGTCGGTGAACATGCCGGTGAA
CTTCCGGCCGACCGCGTGGTCGACCGAGGTCATCTCGAACTTTGCCAGCTACCTGGCGATCGTGCTGCGGGTCGACGAGG
TGACCGATCTCGAGAAGGCGACCGCCATCGTCGCCGGGATCACCGGACCATTGAAGCAATCCGGCGCCGCCGGGTGGGTC
GTGGATCTGCTCGAAGGGGGAAAGGTGTTGCCGGCGATGCTCAAGCGCCAACTTCAGCTGCTTCTCCCCTTGGTCGAAGA
TCGGTTCGTCGAAAGCGTCTGTCTGTCCAACCTGGGCCGCGTCGACGTCCCCGCTTTCGGGGGCGAGGCCGGGGACACCA
CTGAGGTGTGGTTCAGTCCGACGGCGGCCATGAGCGTCATGCCGATCGGGGTTGGCCTCGTCGGCTTCGGAGGAACGCTG
CGCGCCATGTTCCGCGGCGACGGGCGAACCATCGGCGGCGAGGCGCTGGGCCGCTTCGCCGCACTGTATCGCGACACACT
GCTGACCTGA

Upstream 100 bases:

>100_bases
AGCGCCGGCAACGGATGGTCGGCGAGGGCGCTGATCGGGCAACGATGCCCAGGCCAGGCGGCCCCAGCGAACGCCGCACC
GGCTGGAGGAAGATAGCCCC

Downstream 100 bases:

>100_bases
GGGCCCGGCATGACCGACAACGAGTGCCCGGCCGACAGCCGACGGCGCCATGTCCTGCGGCTCGCCCTGTTCGCCGGGAT
TTTGCTGGGGCTGTTCTACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALRAAVAKHALARARLGRASLTARTLYWEVPDRADHLA
VEITDEPVGEVRSRFYARAPELHRSPVFAVAVVRETVGDRLLLNFHHAAFDGMGGLRLLLSLARAYAGEPDEVGGPPIEE
ARNLKGVAGSRDLFDVLIRARGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMATAVARRPEGATVNDLAMAA
LALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNFASYLAIVLRVDEVTDLEKATAIVAGITGPLKQSGAAGWV
VDLLEGGKVLPAMLKRQLQLLLPLVEDRFVESVCLSNLGRVDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGTL
RAMFRGDGRTIGGEALGRFAALYRDTLLT

Sequences:

>Translated_429_residues
MTQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALRAAVAKHALARARLGRASLTARTLYWEVPDRADHLA
VEITDEPVGEVRSRFYARAPELHRSPVFAVAVVRETVGDRLLLNFHHAAFDGMGGLRLLLSLARAYAGEPDEVGGPPIEE
ARNLKGVAGSRDLFDVLIRARGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMATAVARRPEGATVNDLAMAA
LALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNFASYLAIVLRVDEVTDLEKATAIVAGITGPLKQSGAAGWV
VDLLEGGKVLPAMLKRQLQLLLPLVEDRFVESVCLSNLGRVDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGTL
RAMFRGDGRTIGGEALGRFAALYRDTLLT
>Mature_428_residues
TQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALRAAVAKHALARARLGRASLTARTLYWEVPDRADHLAV
EITDEPVGEVRSRFYARAPELHRSPVFAVAVVRETVGDRLLLNFHHAAFDGMGGLRLLLSLARAYAGEPDEVGGPPIEEA
RNLKGVAGSRDLFDVLIRARGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMATAVARRPEGATVNDLAMAAL
ALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNFASYLAIVLRVDEVTDLEKATAIVAGITGPLKQSGAAGWVV
DLLEGGKVLPAMLKRQLQLLLPLVEDRFVESVCLSNLGRVDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGTLR
AMFRGDGRTIGGEALGRFAALYRDTLLT

Specific function: Unknown

COG id: COG4908

COG function: function code R; Uncharacterized protein containing a NRPS condensation (elongation) domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2305_MYCTU (Q50660)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   E70734
- RefSeq:   NP_216821.1
- RefSeq:   NP_336834.1
- ProteinModelPortal:   Q50660
- EnsemblBacteria:   EBMYCT00000003014
- EnsemblBacteria:   EBMYCT00000069074
- GeneID:   885752
- GeneID:   924058
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2362
- KEGG:   mtu:Rv2305
- TIGR:   MT2362
- TubercuList:   Rv2305
- GeneTree:   EBGT00050000018654
- HOGENOM:   HBG131024
- OMA:   HLALRWS
- ProtClustDB:   CLSK791767
- InterPro:   IPR001242

Pfam domain/function: PF00668 Condensation

EC number: NA

Molecular weight: Translated: 46125; Mature: 45993

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALRAAVAKHALARARLGR
CCCEEEEEEHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ASLTARTLYWEVPDRADHLAVEITDEPVGEVRSRFYARAPELHRSPVFAVAVVRETVGDR
HHEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCE
LLLNFHHAAFDGMGGLRLLLSLARAYAGEPDEVGGPPIEEARNLKGVAGSRDLFDVLIRA
EEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
RGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMATAVARRPEGATVNDLAMAA
HCCCCCCCCCHHCCEECCCCCCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHH
LALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNFASYLAIVLRVDEVTDLEKA
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIVAGITGPLKQSGAAGWVVDLLEGGKVLPAMLKRQLQLLLPLVEDRFVESVCLSNLGR
HHHHHCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGTLRAMFRGDGRTIGGEALGRFA
CCCCCCCCCCCCCCEEEECCCHHHEEEECCCEEECCCHHHHHEECCCCCEECHHHHHHHH
ALYRDTLLT
HHHHHHHCC
>Mature Secondary Structure 
TQTLRLTALDEMFITDDIDIVPSVQIEARVSGRFDLDRLAAALRAAVAKHALARARLGR
CCEEEEEEHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ASLTARTLYWEVPDRADHLAVEITDEPVGEVRSRFYARAPELHRSPVFAVAVVRETVGDR
HHEEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCE
LLLNFHHAAFDGMGGLRLLLSLARAYAGEPDEVGGPPIEEARNLKGVAGSRDLFDVLIRA
EEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHH
RGLAKPAIDRKRTTRVAPDGGSPDGPRFVFAPLTIESDEMATAVARRPEGATVNDLAMAA
HCCCCCCCCCHHCCEECCCCCCCCCCEEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHH
LALTILQWNRTHDVPAADSVSVNMPVNFRPTAWSTEVISNFASYLAIVLRVDEVTDLEKA
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIVAGITGPLKQSGAAGWVVDLLEGGKVLPAMLKRQLQLLLPLVEDRFVESVCLSNLGR
HHHHHCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VDVPAFGGEAGDTTEVWFSPTAAMSVMPIGVGLVGFGGTLRAMFRGDGRTIGGEALGRFA
CCCCCCCCCCCCCCEEEECCCHHHEEEECCCEEECCCHHHHHEECCCCCEECHHHHHHHH
ALYRDTLLT
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036