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The map label for this gene is murG [H]

Identifier: 148823362

GI number: 148823362

Start: 2425680

End: 2426912

Strand: Reverse

Name: murG [H]

Synonym: TBFG_12183

Alternate gene names: 148823362

Gene position: 2426912-2425680 (Counterclockwise)

Preceding gene: 148823363

Following gene: 148823361

Centisome position: 54.85

GC content: 74.05

Gene sequence:

>1233_bases
GTGAAGGACACGGTCAGCCAGCCGGCCGGCGGGCGCGGGGCAACGGCGCCCCGGCCCGCCGATGCCGCCTCGCCGTCTTG
TGGTTCCTCGCCGTCTGCTGATTCCGTGTCGGTCGTTCTCGCCGGCGGCGGGACCGCCGGGCACGTCGAGCCCGCCATGG
CCGTCGCCGACGCCTTGGTCGCGTTGGATCCGCGCGTCCGGATTACCGCGTTGGGCACCCTCCGTGGACTAGAGACCAGG
CTGGTGCCCCAGCGCGGCTACCACCTGGAGCTGATCACGGCGGTGCCGATGCCGCGCAAGCCCGGCGGCGACCTGGCCCG
GCTGCCGTCGCGGGTGTGGCGCGCCGTCCGGGAGGCCCGGGACGTGCTCGACGATGTCGACGCCGACGTCGTCGTCGGTT
TCGGTGGGTACGTCGCGCTACCGGCTTACCTAGCCGCTCGCGGCCTGCCTTTGCCGCCCCGGCGCCGGCGCCGGATCCCG
GTGGTGATCCACGAAGCCAACGCCAGGGCGGGACTGGCCAACCGGGTCGGCGCCCATACCGCGGACCGGGTGCTCTCCGC
GGTGCCGGATTCCGGGCTGCGGCGCGCCGAGGTGGTTGGGGTCCCGGTCCGTGCGTCGATCGCCGCGCTGGACCGCGCGG
TGCTGCGAGCCGAGGCGCGGGCACACTTCGGCTTCCCCGACGACGCGCGGGTGCTGCTGGTGTTCGGGGGTTCGCAGGGC
GCGGTCTCGCTCAACCGGGCGGTGTCCGGCGCCGCCGCCGACCTGGCCGCCGCCGGTGTTTGCGTGCTGCATGCCCATGG
ACCCCAGAACGTGCTGGAGTTGCGCCGTCGGGCTCAAGGTGACCCACCGTACGTGGCGGTGCCCTATTTGGACCGGATGG
AGCTGGCCTACGCCGCCGCCGATCTGGTGATCTGCCGGGCCGGGGCGATGACGGTCGCCGAAGTATCCGCCGTCGGTCTG
CCGGCCATCTACGTGCCGCTGCCGATCGGCAACGGTGAACAGCGGCTGAATGCGTTGCCGGTAGTCAATGCCGGCGGCGG
CATGGTGGTCGCCGACGCCGCCCTGACCCCCGAGTTGGTGGCCCGCCAGGTTGCCGGGCTGCTCACCGACCCCGCGCGGC
TGGCCGCGATGACCGCGGCCGCAGCCAGGGTGGGACATCGCGATGCCGCGGGCCAGGTGGCCCGGGCCGCGGTGGCCGTC
GCCACCGGGGCCGGTGCCAGGACAACGACGTGA

Upstream 100 bases:

>100_bases
ATCCGCCGGTTCGTCGATCAGTGCATCATGGAGCTGGCCAGCGGTACGCGGGCCAGCGTCGCACACGGCGCGTTCGGGCA
TTGGAAGGTCAGCGTTACGG

Downstream 100 bases:

>100_bases
GCACCGAGCAGTTGCCGCCCGATCTGCGGCGGGTGCACATGGTCGGCATCGGCGGAGCTGGCATGTCGGGCATCGCCCGA
ATCCTGCTGGACCGCGGCGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVEPAMAVADALVALDPRVRITALGTLRGLETR
LVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIP
VVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQG
AVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAADLVICRAGAMTVAEVSAVGL
PAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAAVAV
ATGAGARTTT

Sequences:

>Translated_410_residues
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVEPAMAVADALVALDPRVRITALGTLRGLETR
LVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIP
VVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQG
AVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAADLVICRAGAMTVAEVSAVGL
PAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAAVAV
ATGAGARTTT
>Mature_410_residues
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVEPAMAVADALVALDPRVRITALGTLRGLETR
LVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREARDVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIP
VVIHEANARAGLANRVGAHTADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQG
AVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAADLVICRAGAMTVAEVSAVGL
PAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELVARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAAVAV
ATGAGARTTT

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=374, Percent_Identity=37.9679144385027, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 41847; Mature: 41847

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVEPAMAVADALV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
ALDPRVRITALGTLRGLETRLVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREAR
HCCCCEEEEEEEHHHCCHHEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
DVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIPVVIHEANARAGLANRVGAHT
HHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCHHHHHCCHH
ADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQG
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
AVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAA
CEEHHHHHCCHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
DLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELV
HHHEECCCCCHHHHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCCCEEEECCCCCHHHH
ARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAAVAVATGAGARTTT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure
MKDTVSQPAGGRGATAPRPADAASPSCGSSPSADSVSVVLAGGGTAGHVEPAMAVADALV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
ALDPRVRITALGTLRGLETRLVPQRGYHLELITAVPMPRKPGGDLARLPSRVWRAVREAR
HCCCCEEEEEEEHHHCCHHEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
DVLDDVDADVVVGFGGYVALPAYLAARGLPLPPRRRRRIPVVIHEANARAGLANRVGAHT
HHHHHCCCCEEEECCCHHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCHHHHHCCHH
ADRVLSAVPDSGLRRAEVVGVPVRASIAALDRAVLRAEARAHFGFPDDARVLLVFGGSQG
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
AVSLNRAVSGAAADLAAAGVCVLHAHGPQNVLELRRRAQGDPPYVAVPYLDRMELAYAAA
CEEHHHHHCCHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
DLVICRAGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGGMVVADAALTPELV
HHHEECCCCCHHHHHHHCCCCEEEEEECCCCCHHHHCCCCEEECCCCEEEECCCCCHHHH
ARQVAGLLTDPARLAAMTAAAARVGHRDAAGQVARAAVAVATGAGARTTT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]