Click here to switch to the map view.

The map label for this gene is metH

Identifier: 148823335

GI number: 148823335

Start: 2396050

End: 2399628

Strand: Reverse

Name: metH

Synonym: TBFG_12156

Alternate gene names: 148823335

Gene position: 2399628-2396050 (Counterclockwise)

Preceding gene: 148823337

Following gene: 148823333

Centisome position: 54.24

GC content: 65.13

Gene sequence:

>3579_bases
GTGACTGCGGCCGACAAGCACCTCTACGACACCGATCTGCTCGACGTCTTGTCGCAGCGAGTGATGGTCGGCGACGGTGC
AATGGGAACCCAACTACAGGCCGCGGACCTCACGCTCGACGACTTCCGCGGCCTGGAGGGCTGCAACGAGATCCTCAACG
AAACCCGCCCTGACGTGCTGGAAACCATTCACCGCAACTATTTCGAAGCGGGCGCCGACGCCGTCGAGACGAACACGTTT
GGCTGCAACCTGTCCAACCTCGGCGACTACGACATCGCCGACAGGATCCGCGATCTATCACAGAAGGGCACCGCGATCGC
ACGCCGGGTGGCCGACGAGCTGGGCAGTCCCGACCGCAAGCGCTACGTGCTGGGGTCGATGGGGCCGGGCACCAAGCTGC
CGACTCTGGGCCACACCGAATACGCGGTGATCCGCGACGCCTACACCGAGGCCGCGCTGGGCATGCTGGACGGCGGAGCC
GACGCCATCCTGGTGGAAACCTGCCAGGACCTACTGCAGCTGAAGGCGGCGGTGTTGGGGTCGCGGCGGGCGATGACGCG
GGCCGGGCGGCACATTCCGGTGTTTGCCCACGTCACCGTCGAGACCACCGGCACCATGCTGCTGGGCAGCGAGATCGGGG
CGGCGTTGACCGCTGTCGAGCCGCTCGGTGTGGACATGATCGGCTTGAACTGCGCGACGGGTCCGGCCGAGATGAGCGAG
CACCTGCGCCACCTGTCCCGGCACGCCCGCATCCCGGTGTCGGTGATGCCCAACGCCGGGTTGCCGGTGCTGGGCGCCAA
GGGCGCCGAATATCCGTTGCTGCCCGACGAATTGGCCGAGGCGCTGGCCGGCTTCATCGCCGAGTTCGGGCTCTCGCTGG
TCGGTGGCTGCTGCGGCACCACCCCGGCCCATATCCGCGAAGTGGCTGCCGCGGTTGCGAACATCAAGCGTCCCGAGCGA
CAGGTCAGCTACGAGCCGTCGGTGTCGTCGCTGTACACCGCAATCCCGTTCGCCCAGGACGCCTCGGTTCTGGTGATCGG
GGAGCGAACGAACGCCAACGGCTCCAAGGGTTTTCGTGAGGCGATGATCGCCGAGGACTACCAGAAGTGCCTGGACATCG
CCAAGGACCAGACCCGCGACGGCGCCCACCTGCTGGACCTGTGTGTGGACTACGTGGGCCGCGACGGTGTGGCCGACATG
AAGGCGCTGGCCAGCCGGCTGGCCACGTCCTCGACGCTGCCGATCATGCTGGACTCCACCGAAACCGCGGTGCTGCAGGC
GGGTTTGGAGCATCTGGGTGGCCGTTGCGCGATCAACTCGGTGAACTACGAGGACGGCGACGGCCCGGAATCGCGCTTTG
CCAAGACCATGGCGCTGGTCGCCGAGCACGGCGCGGCGGTGGTCGCGCTGACCATCGACGAAGAGGGCCAGGCCCGCACC
GCGCAGAAGAAGGTCGAGATCGCCGAGCGGCTGATCAACGACATCACCGGCAACTGGGGCGTCGACGAATCATCCATCCT
CATCGACACCTTGACGTTCACCATCGCCACCGGTCAGGAGGAGTCCCGCCGCGACGGCATCGAGACCATCGAGGCGATCC
GCGAACTGAAAAAGCGCCACCCGGATGTGCAGACCACACTTGGTCTGTCCAACATCTCGTTTGGTCTCAATCCCGCAGCG
CGCCAGGTGCTCAACTCGGTGTTCCTGCACGAATGCCAAGAAGCGGGGCTGGATTCGGCGATCGTGCACGCGTCGAAGAT
CCTGCCGATGAACCGGATTCCCGAGGAGCAACGCAACGTCGCCCTGGATCTGGTCTACGACCGCCGCCGCGAGGACTACG
ATCCGCTGCAGGAGCTGATGCGGCTGTTCGAAGGCGTGTCGGCGGCCTCCTCGAAAGAGGACCGACTGGCTGAACTAGCT
GGGCTGCCGCTGTTCGAACGGCTGGCCCAACGCATCGTCGACGGCGAGCGCAACGGCCTGGACGCCGATCTCGACGAGGC
GATGACGCAAAAGCCGCCGCTTCAGATCATCAACGAACATCTGCTGGCCGGCATGAAGACGGTCGGCGAGCTCTTCGGCT
CCGGCCAGATGCAGCTGCCGTTCGTGCTGCAGTCGGCGGAGGTAATGAAAGCCGCCGTCGCGTATCTGGAACCGCACATG
GAGCGCTCGGACGACGATTCGGGCAAGGGACGCATCGTGCTGGCCACCGTCAAGGGCGACGTGCACGACATCGGCAAGAA
CCTGGTCGACATCATCTTGAGCAACAACGGCTACGAAGTGGTCAACATCGGCATCAAGCAGCCAATCGCCACCATCCTCG
AAGTCGCCGAGGACAAGAGCGCCGACGTGGTCGGCATGTCGGGCCTGCTGGTGAAGTCGACCGTGGTGATGAAGGAAAAC
CTCGAGGAGATGAACACCCGGGGAGTCGCCGAAAAGTTCCCGGTGCTGCTCGGCGGCGCGGCGTTGACGCGCAGCTATGT
CGAAAACGACCTGGCCGAGATCTACCAGGGCGAAGTGCATTACGCGCGAGACGCTTTCGAGGGCCTGAAGTTGATGGACA
CCATCATGAGCGCCAAGCGCGGCGAGGCGCCCGACGAAAACAGCCCGGAAGCCATTAAGGCGCGTGAGAAAGAAGCCGAA
CGTAAGGCCCGCCACCAGCGATCCAAACGCATTGCCGCACAGCGCAAAGCCGCCGAAGAACCAGTCGAGGTGCCCGAACG
CTCCGATGTCGCGGCCGACATCGAGGTCCCGGCGCCGCCGTTCTGGGGTTCGCGGATCGTCAAGGGCCTGGCGGTGGCCG
ACTACACCGGTCTGCTCGATGAGCGCGCATTGTTTTTGGGCCAGTGGGGTTTACGCGGCCAGCGCGGCGGTGAGGGTCCG
TCCTACGAAGATCTCGTCGAGACCGAGGGCCGGCCGCGGCTGCGGTACTGGTTGGACCGGCTGTCCACCGACGGCATCTT
GGCGCACGCCGCCGTGGTGTACGGCTATTTCCCGGCGGTGTCCGAGGGCAACGACATCGTGGTGCTCACCGAGCCCAAGC
CCGACGCCCCGGTGCGCTACCGGTTTCACTTCCCGCGCCAGCAGCGCGGTCGGTTTTTGTGCATTGCCGATTTCATCCGC
TCGCGGGAGCTGGCCGCCGAGCGTGGCGAGGTTGACGTGCTGCCGTTCCAGCTGGTGACCATGGGTCAGCCGATCGCGGA
TTTCGCCAACGAGCTGTTCGCGTCCAACGCCTACCGCGACTACCTGGAGGTGCACGGTATCGGCGTGCAGCTCACCGAGG
CGCTGGCCGAGTACTGGCACCGGCGGATCCGTGAGGAGCTCAAGTTCTCCGGGGATCGGGCGATGGCGGCCGAGGATCCG
GAGGCGAAAGAAGACTATTTCAAGCTCGGCTACCGCGGTGCTCGCTTTGCCTTCGGCTACGGCGCATGCCCGGATCTGGA
GGACCGCGCCAAGATGATGGCGCTGCTGGAGCCCGAACGCATCGGTGTGACGTTATCCGAGGAATTACAGCTGCATCCCG
AACAGTCGACCGACGCGTTCGTCCTGCACCATCCGGAAGCCAAGTACTTCAACGTTTAA

Upstream 100 bases:

>100_bases
CTGAGACTCTTGTGGCAGCTGTGACCGATGCGACGTCGCGGTACCTGGCAGAGCGCTGTCAACGACTGAGGAAATTTCAT
AGGCCGACTATCCTTGCCAT

Downstream 100 bases:

>100_bases
TCTGACCCGTCCCACGTGTGCGGAAGCATCGGCTGCGACAGGACGTCGGCGAATCCGCCGCCTAGGTGAGTAAGCCCGGT
CGCTGATCCGGGCGCCGATT

Product: 5-methyltetrahydrofolate-homocystein methyltransferase metH

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS

Number of amino acids: Translated: 1192; Mature: 1191

Protein sequence:

>1192_residues
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVLETIHRNYFEAGADAVETNTF
GCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRKRYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGA
DAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGTTPAHIREVAAAVANIKRPER
QVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADM
KALASRLATSSTLPIMLDSTETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAA
RQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELA
GLPLFERLAQRIVDGERNGLDADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKEN
LEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAE
RKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRYRFHFPRQQRGRFLCIADFIR
SRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDP
EAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV

Sequences:

>Translated_1192_residues
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVLETIHRNYFEAGADAVETNTF
GCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRKRYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGA
DAILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGTTPAHIREVAAAVANIKRPER
QVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADM
KALASRLATSSTLPIMLDSTETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAA
RQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELA
GLPLFERLAQRIVDGERNGLDADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKEN
LEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAE
RKARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRYRFHFPRQQRGRFLCIADFIR
SRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDP
EAKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
>Mature_1191_residues
TAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVLETIHRNYFEAGADAVETNTFG
CNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRKRYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGAD
AILVETCQDLLQLKAAVLGSRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEH
LRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGTTPAHIREVAAAVANIKRPERQ
VSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMK
ALASRLATSSTLPIMLDSTETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQARTA
QKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAAR
QVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNVALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAG
LPLFERLAQRIVDGERNGLDADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHME
RSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKENL
EEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVHYARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAER
KARHQRSKRIAAQRKAAEEPVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGPS
YEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRYRFHFPRQQRGRFLCIADFIRS
RELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPE
AKEDYFKLGYRGARFAFGYGACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain

Homologues:

Organism=Homo sapiens, GI169790923, Length=1250, Percent_Identity=31.2, Blast_Score=492, Evalue=1e-138,
Organism=Escherichia coli, GI1790450, Length=1225, Percent_Identity=31.4285714285714, Blast_Score=531, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17535405, Length=1245, Percent_Identity=31.1646586345381, Blast_Score=513, Evalue=1e-145,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): METH_MYCTU (O33259)

Other databases:

- EMBL:   BX842578
- PIR:   G70513
- RefSeq:   NP_216640.1
- ProteinModelPortal:   O33259
- EnsemblBacteria:   EBMYCT00000000678
- GeneID:   888711
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv2124c
- TubercuList:   Rv2124c
- GeneTree:   EBGT00050000017538
- HOGENOM:   HBG289648
- OMA:   YVTDASR
- ProtClustDB:   CLSK872016
- BRENDA:   2.1.1.13
- GO:   GO:0005829
- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223
- Gene3D:   G3DSA:3.40.50.280
- Gene3D:   G3DSA:3.20.20.20
- Gene3D:   G3DSA:3.10.196.10
- Gene3D:   G3DSA:1.10.1240.10
- Gene3D:   G3DSA:3.20.20.330
- PIRSF:   PIRSF000381
- TIGRFAMs:   TIGR02082

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans; SSF52242 Cbl-bd; SSF51717 DHP_synth_like; SSF56507 Met_synth_B12; SSF47644 Met_synth_Cbl-bd; SSF82282 S_methyl_trans

EC number: =2.1.1.13

Molecular weight: Translated: 130324; Mature: 130193

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50974 ADOMET_ACTIVATION; PS51332 B12_BINDING; PS51337 B12_BINDING_NTER; PS50970 HCY; PS50972 PTERIN_BINDING; PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 787-787 BINDING 940-940 BINDING 1135-1135 BINDING 1139-1139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
CCCCCCCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCHHHHCCHHHHHHHHHCCCHHHH
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRK
HHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HHHHHHHCCCCCEEEEEEEEECCCCEEECHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGT
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TPAHIREVAAAVANIKRPERQVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
CHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHH
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCH
ETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHH
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRH
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHC
PDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNV
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHCE
ALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLFERLAQRIVDGERNGL
EEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
DADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHC
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCC
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVH
CCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCHH
YARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARHQRSKRIAAQRKAAEE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRY
CHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEE
RFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRD
EEECCHHHCCCEEEHHHHHHHHHHHHHCCCEEEECHHHHHCCCCHHHHHHHHHHCCHHHH
YLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKEDYFKLGYRGARFAFGY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECC
GACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
CCCCCHHHHHHHHHHCCHHHCCCEEHHHHEECCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TAADKHLYDTDLLDVLSQRVMVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
CCCCCCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCHHHHCCHHHHHHHHHCCCHHHH
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSQKGTAIARRVADELGSPDRK
HHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SRRAMTRAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HHHHHHHCCCCCEEEEEEEEECCCCEEECHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
HLRHLSRHARIPVSVMPNAGLPVLGAKGAEYPLLPDELAEALAGFIAEFGLSLVGGCCGT
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
TPAHIREVAAAVANIKRPERQVSYEPSVSSLYTAIPFAQDASVLVIGERTNANGSKGFRE
CHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHH
AMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDST
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCH
ETAVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMALVAEHGAAVVALTIDEEGQART
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHH
AQKKVEIAERLINDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRELKKRH
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHC
PDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRNV
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHCE
ALDLVYDRRREDYDPLQELMRLFEGVSAASSKEDRLAELAGLPLFERLAQRIVDGERNGL
EEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
DADLDEAMTQKPPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHM
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHC
ERSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKS
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCC
ADVVGMSGLLVKSTVVMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEIYQGEVH
CCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCHH
YARDAFEGLKLMDTIMSAKRGEAPDENSPEAIKAREKEAERKARHQRSKRIAAQRKAAEE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVEVPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGLLDERALFLGQWGLRGQRGGEGP
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGNDIVVLTEPKPDAPVRY
CHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEE
RFHFPRQQRGRFLCIADFIRSRELAAERGEVDVLPFQLVTMGQPIADFANELFASNAYRD
EEECCHHHCCCEEEHHHHHHHHHHHHHCCCEEEECHHHHHCCCCHHHHHHHHHHCCHHHH
YLEVHGIGVQLTEALAEYWHRRIREELKFSGDRAMAAEDPEAKEDYFKLGYRGARFAFGY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECC
GACPDLEDRAKMMALLEPERIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
CCCCCHHHHHHHHHHCCHHHCCCEEHHHHEECCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230