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The map label for this gene is sigC [H]

Identifier: 148823283

GI number: 148823283

Start: 2341178

End: 2342113

Strand: Direct

Name: sigC [H]

Synonym: TBFG_12105

Alternate gene names: 148823283

Gene position: 2341178-2342113 (Clockwise)

Preceding gene: 148823281

Following gene: 148823289

Centisome position: 52.91

GC content: 67.41

Gene sequence:

>936_bases
ATGCGAACCGCTCATCGGCGCGGTATTCGATCGCGGCGGTGGTGCCGGTGGCGGGCACATACACCCCAAGCCGGGCATCG
TATCTGCGCTCCAGCTCGGCGAAGCGATCCGCCAGATCCGCTCCGGCCGGCAAGGTTGTCGATGCCGGACGGGCCCCGCT
CGCATGCCGTGCACACCCCGTCACGGAAACCAGCATTGCCATCGCTACCAGCAGTTCGCGACGACCGAATCCTCTGTTGC
GCATGCCGTAGTATCACACGCGCGCAGATGGCAGGCGCCAAAGCGCATTCGACGCCGCGCTCCCCCGGCTGCTCGGCGGC
GGGATCTACGACGACCGGTCGTAGACTGACCGGACCTGCCGGGCTATGGTTTATGCCCATGACCGCGACGGCAAGCGACG
ACGAGGCCGTTACCGCACTCGCCTTGTCGGCGGCCAAGGGGAACGGGCGGGCCCTTGAGGCGTTTATCAAAGCCACCCAG
CAAGACGTGTGGCGGTTCGTCGCCTATCTGTCCGACGTGGGCAGTGCGGACGATCTCACCCAAGAGACATTCCTACGAGC
GATCGGCGCCATCCCGCGGTTTTCCGCACGCTCCAGCGCCCGAACTTGGTTGCTGGCCATCGCGCGCCATGTCGTCGCCG
ATCACATCCGCCACGTCCGATCCCGGCCCCGCACCACCCGCGGCGCGCGTCCCGAACATCTCATAGACGGCGACCGCCAT
GCCCGCGGATTCGAAGACCTCGTCGAGGTAACCACGATGATCGCCGACCTAACCACCGACCAACGGGAAGCGCTGCTGCT
GACCCAGCTGCTCGGGCTGTCCTATGCGGACGCCGCGGCGGTGTGCGGCTGCCCGGTGGGCACCATCCGATCCCGTGTCG
CTCGAGCGCGCGATGCGCTGCTTGCCGACGCGGAGCCCGACGACCTCACCGGCTAG

Upstream 100 bases:

>100_bases
CGAATGTCGTCACTGGTGTAGGTGATCAGTTTGTCCAGATGCGTGAGCGGGTTTTGGTGCAGCACCGCCGCCACGAGCGG
CGCCTTGAACGTGGAGCAGA

Downstream 100 bases:

>100_bases
GCAGACCGGCCACCCACATGGCGGCCCGGTGGACAGAATCGACCGCCGCTACCCCAGCCGGCAGCAGCGGGCGCGCTATC
ATGACCACCGAAATACCCAG

Product: RNA polymerase sigma factor SigC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRTAHRRGIRSRRWCRWRAHTPQAGHRICAPARRSDPPDPLRPARLSMPDGPRSHAVHTPSRKPALPSLPAVRDDRILCC
ACRSITRAQMAGAKAHSTPRSPGCSAAGSTTTGRRLTGPAGLWFMPMTATASDDEAVTALALSAAKGNGRALEAFIKATQ
QDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRH
ARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG

Sequences:

>Translated_311_residues
MRTAHRRGIRSRRWCRWRAHTPQAGHRICAPARRSDPPDPLRPARLSMPDGPRSHAVHTPSRKPALPSLPAVRDDRILCC
ACRSITRAQMAGAKAHSTPRSPGCSAAGSTTTGRRLTGPAGLWFMPMTATASDDEAVTALALSAAKGNGRALEAFIKATQ
QDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRH
ARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG
>Mature_311_residues
MRTAHRRGIRSRRWCRWRAHTPQAGHRICAPARRSDPPDPLRPARLSMPDGPRSHAVHTPSRKPALPSLPAVRDDRILCC
ACRSITRAQMAGAKAHSTPRSPGCSAAGSTTTGRRLTGPAGLWFMPMTATASDDEAVTALALSAAKGNGRALEAFIKATQ
QDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRH
ARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=174, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 33749; Mature: 33749

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAHRRGIRSRRWCRWRAHTPQAGHRICAPARRSDPPDPLRPARLSMPDGPRSHAVHTP
CCCHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SRKPALPSLPAVRDDRILCCACRSITRAQMAGAKAHSTPRSPGCSAAGSTTTGRRLTGPA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLWFMPMTATASDDEAVTALALSAAKGNGRALEAFIKATQQDVWRFVAYLSDVGSADDLT
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRH
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHH
ARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDAL
HCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
LADAEPDDLTG
HCCCCCCCCCC
>Mature Secondary Structure
MRTAHRRGIRSRRWCRWRAHTPQAGHRICAPARRSDPPDPLRPARLSMPDGPRSHAVHTP
CCCHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SRKPALPSLPAVRDDRILCCACRSITRAQMAGAKAHSTPRSPGCSAAGSTTTGRRLTGPA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLWFMPMTATASDDEAVTALALSAAKGNGRALEAFIKATQQDVWRFVAYLSDVGSADDLT
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRH
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHH
ARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDAL
HCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
LADAEPDDLTG
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]