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The map label for this gene is acg

Identifier: 148823248

GI number: 148823248

Start: 2293741

End: 2294736

Strand: Direct

Name: acg

Synonym: TBFG_12069

Alternate gene names: 148823248

Gene position: 2293741-2294736 (Clockwise)

Preceding gene: 148823235

Following gene: 148823250

Centisome position: 51.84

GC content: 63.76

Gene sequence:

>996_bases
ATGCCGGACACCATGGTGACCACCGATGTCATCAAGAGCGCGGTGCAGTTGGCCTGCCGCGCACCGTCGCTCCACAACAG
CCAGCCCTGGCGCTGGATAGCCGAGGACCACACGGTTGCGCTGTTCCTCGACAAGGATCGGGTGCTTTACGCGACCGACC
ACTCCGGCCGGGAAGCGCTGCTGGGGTGCGGCGCCGTACTCGACCACTTTCGGGTGGCGATGGCGGCCGCGGGTACCACC
GCCAATGTGGAACGGTTTCCCAACCCCAACGATCCTTTGCATCTGGCGTCAATTGACTTCAGCCCGGCCGATTTCGTCAC
CGAGGGCCACCGTCTAAGGGCGGATGCGATCCTACTGCGCCGTACCGACCGGCTGCCTTTCGCCGAGCCGCCGGATTGGG
ACTTGGTGGAGTCGCAGTTGCGCACGACCGTCACCGCCGACACGGTGCGCATCGACGTCATCGCCGACGATATGCGTCCC
GAACTGGCGGCGGCGTCCAAACTCACCGAATCGCTGCGGCTCTACGATTCGTCGTATCATGCCGAACTCTTTTGGTGGAC
AGGGGCTTTTGAGACTTCTGAGGGCATACCGCACAGTTCATTGGTATCGGCGGCCGAAAGTGACCGGGTCACCTTCGGAC
GCGACTTCCCGGTCGTCGCCAACACCGATAGGCGCCCGGAGTTTGGCCACGACCGCTCTAAGGTCCTGGTGCTCTCCACC
TACGACAACGAACGCGCCAGCCTACTGCGCTGCGGCGAGATGCTTTCCGCCGTATTGCTTGACGCCACCATGGCTGGGCT
TGCCACCTGCACGCTGACCCACATCACCGAACTGCACGCCAGCCGAGACCTGGTCGCAGCGCTGATTGGGCAGCCCGCAA
CTCCGCAAGCCTTGGTTCGCGTCGGTCTGGCCCCGGAGATGGAAGAGCCGCCACCGGCAACGCCTCGGCGACCAATCGAT
GAAGTGTTTCACGTTCGGGCTAAGGATCACCGGTAG

Upstream 100 bases:

>100_bases
GTCCGCGCCCGTCGGTGATCCACTTGGGGACCATTGACCCTGTTGTCTGCCAACCGCCGTTCAGAAAGATCGGGGTGATA
TCGAACAGCGGAGGTTGATC

Downstream 100 bases:

>100_bases
CGGGCGCCGCCGGGACCGCGTCTAAGCACCGCAGCTGAATCGGGCGGATGATGTGTCGATGAGCGGATCCGGCGATGGCG
ACGGTGTCGCGCGGTTGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTT
ANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRP
ELAAASKLTESLRLYDSSYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVRVGLAPEMEEPPPATPRRPID
EVFHVRAKDHR

Sequences:

>Translated_331_residues
MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTT
ANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRP
ELAAASKLTESLRLYDSSYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVRVGLAPEMEEPPPATPRRPID
EVFHVRAKDHR
>Mature_330_residues
PDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTA
NVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPE
LAAASKLTESLRLYDSSYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLSTY
DNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVRVGLAPEMEEPPPATPRRPIDE
VFHVRAKDHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACG_MYCTU (O53476)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   G70942
- RefSeq:   NP_216548.1
- RefSeq:   NP_336556.1
- ProteinModelPortal:   O53476
- EnsemblBacteria:   EBMYCT00000001921
- EnsemblBacteria:   EBMYCT00000069243
- GeneID:   887582
- GeneID:   924658
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2091
- KEGG:   mtu:Rv2032
- TIGR:   MT2091
- TubercuList:   Rv2032
- GeneTree:   EBGT00050000015619
- HOGENOM:   HBG696381
- OMA:   HAELIGW
- ProtClustDB:   CLSK791577
- GO:   GO:0005829
- InterPro:   IPR000415

Pfam domain/function: PF00881 Nitroreductase; SSF55469 Nitroreductase

EC number: NA

Molecular weight: Translated: 36560; Mature: 36428

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: BINDING 316-316

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREAL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEECCEEEEEECCCCCHHH
LGCGAVLDHFRVAMAAAGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLR
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCHHHHCCCCEEEHHEEEEE
RTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPELAAASKLTESLRLYDSSYH
ECCCCCCCCCCCHHHHHHHHHHEEEECEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
AELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
EEEEEEECCEECCCCCCHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCEEEEEEE
YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHE
VGLAPEMEEPPPATPRRPIDEVFHVRAKDHR
ECCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
PDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREAL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEEECCEEEEEECCCCCHHH
LGCGAVLDHFRVAMAAAGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLR
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCHHHHCCCCEEEHHEEEEE
RTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPELAAASKLTESLRLYDSSYH
ECCCCCCCCCCCHHHHHHHHHHEEEECEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
AELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
EEEEEEECCEECCCCCCHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCEEEEEEE
YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHE
VGLAPEMEEPPPATPRRPIDEVFHVRAKDHR
ECCCCCCCCCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036