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The map label for this gene is 148823223

Identifier: 148823223

GI number: 148823223

Start: 2264871

End: 2266196

Strand: Reverse

Name: 148823223

Synonym: TBFG_12040

Alternate gene names: NA

Gene position: 2266196-2264871 (Counterclockwise)

Preceding gene: 148823226

Following gene: 148823222

Centisome position: 51.22

GC content: 62.97

Gene sequence:

>1326_bases
ATGGACGAGATCGAGAGCCTTATCGGGCTGCGGCCAACCCCGCTGACCTGGCCGGTCGTTATCGCCGGCGACTTTCTAGG
CGTGTGGGACCCACCACCGAGTCTCCCGGGGGCGGCTAACCATGAAATATCAGCGCCTACCGCTAGAATTTCATGCATGT
TGATCGAACGCCGCGACGCCGCCGCGCGGTTGCGACGCGCGCTACACCGAGCGCCGGTGGTGTTGCTTACCGGACCTCGT
CAAGCCGGCAAGACCACCCTTAGCCGGCTGGTGGGCAAGTCCGCACCCGAATGTACGTTTGACGCCGAAAATCCCGTCGA
CGCGACACGGCTTGCCGACCCGATGTTGGCTTTATCCGGCCTTAGCGGGTTGATCACGATCGACGAGGCGCAACGGATTC
CGGATCTGTTTCCGGTCCTACGCGTGCTCGTCGACAGGCCTGTCATGCCGGCCCGGTTTCTTATCCTGGGTAGCGCCTCA
CCCGATCTTGTCGGGCTGGCGTCCGAAAGTTTGGCCGGACGCGTCGAGTTGGTGGAGTTGTCCGGCCTGACGGTCCGCGA
CGTCGGATCCTCGGCCGCCGATCGCCTCTGGTTGCGTGGGGGTCTACCGCCCTCGTTCACGGCACGCTCCAACGAGGACT
CCGCGGCGTGGCGCGACGGCTACATCACCACGTTTCTGGAGCGCGATCTCGCCCAGCTTGGTGTGCGCATTCCGGCCGCG
ACGATGCGGCGCGCGTGGACGATGCTCGCCCACTACCATGGCCAGCTCTTCAGCGGCGCAGAACTTGCCCGCTCACTCGA
CGTTGCTCAGACGACGGCGCGGCGATACCTCGATGCGCTCACCGATGCACTCGTCGTCCGTCAGCTGACGCCCTGGTTCG
CCAACATCGGAAAGCGACAACGCCGATCACCCAAGATCTACATCCGGGACACCGGTTTGTTGCACAGGTTGCTCGGTATC
GACGATCGGCTTGCCCTCGAACGCAATCCGAAGCTCGGCGCGAGCTGGGAGGGGTTCGTGCTCGAGCAGCTTGCGGCCCT
GCTCGCCCCGAATCCGCTGTATTACTGGCGCACCCAGCAAGACGCCGAACTCGATCTCTATGTCGAATTATCTGGCCGTC
CCTATGGATTCGAGATCAAGCGGACGTCTACACCGTCGATTTCCCGGTCGATGCGCTCGGCTCTTGTCGACCTCCAACTG
GCGAGGTTGGCAATCGTCTACCCTGGCGAACACCGCTTTCCCTTGAGCGACACGGTCGTTGCGGTTCCCGCGGATCAGAT
CTTGACCACCGGGAGTGTCGATGAACTTCTCGCGCTCTTGAAATGA

Upstream 100 bases:

>100_bases
CACCACTATACACATTTATGTGTATGAACGTGCTATTTGCTAACCGGCTCGCACGACCGGTGCAGCTTTGCCCTGGTGCA
GGCGATGTGGAGCATGCCTG

Downstream 100 bases:

>100_bases
CGGGCTATCGTAAGTTTATGGCCTGGGGGAGCGTGAATCCCGCTGGCGGTCGGGTGAACCGCCCCGGTTTTCTTGCACCC
CGCGTCGACGTGCCAGTGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALHRAPVVLLTGPR
QAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSGLSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSAS
PDLVGLASESLAGRVELVELSGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAA
TMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQRRSPKIYIRDTGLLHRLLGI
DDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQL
ARLAIVYPGEHRFPLSDTVVAVPADQILTTGSVDELLALLK

Sequences:

>Translated_441_residues
MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALHRAPVVLLTGPR
QAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSGLSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSAS
PDLVGLASESLAGRVELVELSGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAA
TMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQRRSPKIYIRDTGLLHRLLGI
DDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQL
ARLAIVYPGEHRFPLSDTVVAVPADQILTTGSVDELLALLK
>Mature_441_residues
MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALHRAPVVLLTGPR
QAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSGLSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSAS
PDLVGLASESLAGRVELVELSGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAA
TMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQRRSPKIYIRDTGLLHRLLGI
DDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQL
ARLAIVYPGEHRFPLSDTVVAVPADQILTTGSVDELLALLK

Specific function: Unknown

COG id: COG1373

COG function: function code R; Predicted ATPase (AAA+ superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2008_MYCTU (P64923)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   F70759
- RefSeq:   NP_216524.1
- RefSeq:   NP_336527.1
- ProteinModelPortal:   P64923
- EnsemblBacteria:   EBMYCT00000000843
- EnsemblBacteria:   EBMYCT00000070569
- GeneID:   888813
- GeneID:   923372
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2064
- KEGG:   mtu:Rv2008c
- TIGR:   MT2064
- TubercuList:   Rv2008c
- GeneTree:   EBGT00050000018318
- HOGENOM:   HBG336037
- OMA:   WYENISK
- ProtClustDB:   CLSK871994
- InterPro:   IPR013196

Pfam domain/function: PF08279 HTH_11

EC number: NA

Molecular weight: Translated: 48393; Mature: 48393

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDA
CCCHHHHHCCCCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCH
AARLRRALHRAPVVLLTGPRQAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSG
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
LSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSASPDLVGLASESLAGRVELVEL
CCCEEEECHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCHHHCCCEEEEEE
SGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAA
CCCEEECCCCHHHHHHEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCHH
TMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSPKIYIRDTGLLHRLLGIDDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQ
CCCCEEEEECCHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
DAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVV
CCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEE
AVPADQILTTGSVDELLALLK
EECHHHHEECCCHHHHHHHHC
>Mature Secondary Structure
MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDA
CCCHHHHHCCCCCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCH
AARLRRALHRAPVVLLTGPRQAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSG
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
LSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSASPDLVGLASESLAGRVELVEL
CCCEEEECHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCHHHCCCEEEEEE
SGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAA
CCCEEECCCCHHHHHHEEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCHH
TMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSPKIYIRDTGLLHRLLGIDDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQ
CCCCEEEEECCHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
DAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVV
CCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEE
AVPADQILTTGSVDELLALLK
EECHHHHEECCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036