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The map label for this gene is PE_PGRS35 [H]

Identifier: 148823197

GI number: 148823197

Start: 2234498

End: 2236174

Strand: Direct

Name: PE_PGRS35 [H]

Synonym: TBFG_12014

Alternate gene names: 148823197

Gene position: 2234498-2236174 (Clockwise)

Preceding gene: 148823192

Following gene: 148823200

Centisome position: 50.5

GC content: 64.82

Gene sequence:

>1677_bases
GTGTCATTTCTGGTCGTGGTTCCCGAGTTCTTGACGTCCGCGGCAGCGGATGTGGAGAACATAGGTTCCACACTGCGCGC
GGCGAATGCCGCGGCTGCCGCCTCGACCACCGCGCTTGCGGCCGCTGGCGCTGATGAGGTATCGGCGGCGGTGGCAGCGC
TGTTTGCCAGGTTCGGTCAGGAATATCAAGCGGTCAGCGCGCAGGCGAGCGCTTTCCATCAACAGTTCGTGCAGACGCTG
AACTCGGCGTCAGGATCGTATGCGGCCGCGGAGGCCACCATCGCGTCACAGTTGCAGACCGCGCAGCACGATCTGCTGGG
CGCGGTCAATGCACCAACCGAAACGTTGTTGGGGCGTCCGCTAATCGGCGACGGAGCACCCGGGACGGCAACGAGTCCGA
ATGGCGGGGCGGGTGGGCTGCTGTACGGCAACGGCGGCAACGGTTATTCCGCGACGGCGTCGGGGGTCGGCGGCGGGGCC
GGCGGTTCCGCGGGGTTGATCGGCAATGGCGGCGCCGGGGGAGCCGGCGGACCCAACGCCCCCGGGGGAGCCGGCGGCAA
CGGTGGCTGGCTGCTCGGCAACGGCGGGATCGGCGGGCCCGGGGGCGCGTCGAGCATCCCCGGCATGAGTGGTGGAGCCG
GCGGAACCGGCGGTGCCGCAGGACTTTTGGGCTGGGGAGCGAACGGCGGAGCCGGCGGCCTCGGTGATGGAGTCGGTGTC
GATCGTGGCACGGGCGGCGCCGGAGGCCGCGGCGGCCTGTTGTATGGCGGATACGGCGTCAGTGGGCCAGGCGGCGACGG
CAGAACCGTCCCGCTGGAGATAATTCATGTCACAGAGCCGACGGTACATGCCAACGTCAACGGCGGACCGACGTCAACCA
TTCTGGTCGACACCGGATCCGCTGGTCTTGTTGTCTCGCCTGAGGATGTCGGGGGAATCCTGGGAGTGCTTCACATGGGC
CTCCCAACCGGATTGAGCATCAGCGGTTACAGCGGGGGGCTGTACTACATCTTCGCCACGTATACCACGACGGTGGACTT
CGGGAATGGCATCGTCACCGCGCCGACCGCCGTTAATGTCGTCCTCTTGTCCATCCCAACGTCCCCCTTCGCCATTTCGA
CCTACTTCAGCGCCTTGCTGGCCGATCCGACAACAACTCCGTTCGAAGCCTATTTCGGTGCCGTCGGCGTGGACGGCGTT
CTGGGAGTTGGGCCCAATGCGGTGGGACCAGGCCCCAGCATTCCGACGATGGCGTTACCGGGTGACCTCAACCAGGGAGT
GCTCATCGACGCACCCGCAGGTGAGCTCGTGTTCGGTCCCAACCCGCTACCTGCGCCCAACGTCGAGGTCGTCGGATCGC
CGATCACCACCCTGTACGTAAAGATCGATGGTGGGACTCCCATACCCGTCTCCTCGATCATCGATTCCGGTGGGGTAACG
GGAACCATCCCGTCATATGTCATCGGATCCGGAACCCTGCCGGCGAACACAAACATTGAGGTCTACACCAGCCCCGGCGG
TGATCGGCTCTACGCGTTCAACACAAACGATTACCGCCCGACCGTCATTTCATCCGGCCTGATGAATACCGGGTTCTTGC
CCTTCAGATTCCAGCCGGTGTACATCGACTACAGCCCCAGCGGTATAGGGACAACAGTCTTTGATCATCCGGCGTGA

Upstream 100 bases:

>100_bases
TGCTGTGCCGTGCGGTAGCTACTGAAAATCCGAGATGTCAAAGGCAGCGTCTGGATACGCTGTATGCGCGCAGGGATGGT
GATCGAGGCGGAGGGGCGGC

Downstream 100 bases:

>100_bases
TCGAGCCTGTTCGCCGCGAATGTCGCCGCCTGGCTTGTCATCCCCGACTGAACATACGAAACATGCGCCATAATATTGCC
GCCTCCGGTGCATATTGGAT

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTL
NSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGA
GGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGV
DRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMG
LPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGV
LGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVSSIIDSGGVT
GTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA

Sequences:

>Translated_558_residues
MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTL
NSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGA
GGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGV
DRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMG
LPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGV
LGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVSSIIDSGGVT
GTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
>Mature_557_residues
SFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTLN
SASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAG
GSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGVD
RGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGL
PTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVL
GVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVSSIIDSGGVTG
TIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 53728; Mature: 53597

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQ
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH
EYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
LIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNA
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
PGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGV
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
DRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGS
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCEEEEEECCC
AGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNV
CCEEECCHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEEEECCCCEEECCCEEEE
VLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALP
EEEEECCCCEEHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCEECC
GDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVSSIIDSGGVT
CCCCCCEEEECCCCCEEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCHHHHHCCCCCC
GTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPV
CCCCCCEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHEECCCCCCCCCCEEEEEE
YIDYSPSGIGTTVFDHPA
EEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQ
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH
EYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
LIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNA
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
PGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGV
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
DRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGS
CCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCEEEEEECCC
AGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNV
CCEEECCHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEEEECCCCEEECCCEEEE
VLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALP
EEEEECCCCEEHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCEECC
GDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVSSIIDSGGVT
CCCCCCEEEECCCCCEEECCCCCCCCCCEEECCCEEEEEEEECCCCCCCHHHHHCCCCCC
GTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPV
CCCCCCEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHEECCCCCCCCCCEEEEEE
YIDYSPSGIGTTVFDHPA
EEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]