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The map label for this gene is aao

Identifier: 148823117

GI number: 148823117

Start: 2159694

End: 2160656

Strand: Reverse

Name: aao

Synonym: TBFG_11934

Alternate gene names: 148823117

Gene position: 2160656-2159694 (Counterclockwise)

Preceding gene: 148823118

Following gene: 148823114

Centisome position: 48.83

GC content: 66.15

Gene sequence:

>963_bases
GTGGCAATAGGTGAGCAACAGGTCATCGTGATTGGGGCCGGCGTCAGCGGACTGACGTCGGCCATATGCCTGGCCGAGGC
GGGGTGGCCGGTGCGGGTATGGGCGGCCGCATTGCCGCAGCAAACGACATCGGCGGTGGCGGGTGCGGTCTGGGGGCCGC
GGCCGAAGGAACCCGTTGCCAAGGTACGCGGGTGGATCGAACAGTCATTGCACGTGTTTCGCGACTTGGCCAAGGATCCC
GCCACCGGCGTGCGCATGACGCCGGCGCTGAGTGTCGGCGATCGTATCGAGACCGGTGCGATGCCGCCCGGGTTGGAGCT
GATCCCCGACGTGCGGCCGGCTGACCCGGCCGACGTGCCCGGGGGCTTCCGTGCTGGGTTTCATGCCACCTTGCCGATGA
TCGATATGCCCCAGTACCTCGACTGTCTGACCCAGCGATTGGCGGCGACTGGCTGTGAAATCGAAACGCGCCCGCTACGG
TCGCTGGCCGAGGCCGCTGAGGCGGCGCCCATAGTGATCAACTGTGCTGGTCTGGGCGCTCGGGAACTGGCCGGCGACGC
CACGGTCTGGCCGCGGTTCGGCCAGCACGTCGTCCTCACCAATCCAGGTCTAGAGCAACTGTTTATCGAGCGCACCGGCG
GCTCGGAATGGATCTGCTACTTTGCCCACCCGCAGCGTGTAGTCTGCGGCGGCATCAGTATCCCTGGCAGGTGGGACCCC
ACCCCAGAGCCGGAGATAACCGAGCGGATCCTGCAACGGTGTCGCCGCATACAACCACGGCTTGCCGAGGCGGCAGTGAT
TGAGACGATTACCGGGCTGCGTCCTGATCGGCCGTCCGTGCGGGTGGAAGCTGAACCGATCGGGCGAGCGCTGTGCATCC
ACAACTATGGCCACGGAGGTGACGGCGTGACCCTGTCATGGGGTTGTGCGCGGGAGGTGGTCAATCTTGTCGGCGGCGGT
TAA

Upstream 100 bases:

>100_bases
AACTACAAAATCAGCTCGGCATCCTCAACGGCTTACTCGGACCGACTGGAGGGCGAGTGCCTCAGCCCTAACTGACGCTG
GCTTCGGCTACGGTCCTGCT

Downstream 100 bases:

>100_bases
CCCGACACCATGGCGGGTTGGGTGGCACCGGTCGGTTAATGGGTCGGTCAATGCGCGCTGGGAGGCGGCGCCAGTGCGGT
CTCGACCGTTGCATACAGCG

Product: D-amino acid oxidase aao

Products: NA

Alternate protein names: DAAO; DAMOX; DAO

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDP
ATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLR
SLAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDP
TPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG

Sequences:

>Translated_320_residues
MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDP
ATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLR
SLAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDP
TPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG
>Mature_319_residues
AIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVAKVRGWIEQSLHVFRDLAKDPA
TGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVPGGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRS
LAEAAEAAPIVINCAGLGARELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDPT
PEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGGDGVTLSWGCAREVVNLVGGG

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAMOX/DASOX family

Homologues:

Organism=Homo sapiens, GI40217815, Length=324, Percent_Identity=30.2469135802469, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI148539837, Length=334, Percent_Identity=29.940119760479, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI40217827, Length=219, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71999501, Length=319, Percent_Identity=27.2727272727273, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17559850, Length=331, Percent_Identity=26.8882175226586, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71986554, Length=331, Percent_Identity=27.4924471299094, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920852, Length=337, Percent_Identity=27.5964391691395, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24652525, Length=334, Percent_Identity=28.4431137724551, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAO_MYCTU (O07727)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   F70518
- RefSeq:   NP_216421.1
- RefSeq:   NP_336413.1
- HSSP:   P00371
- ProteinModelPortal:   O07727
- SMR:   O07727
- EnsemblBacteria:   EBMYCT00000002504
- EnsemblBacteria:   EBMYCT00000069332
- GeneID:   885504
- GeneID:   923610
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1956
- KEGG:   mtu:Rv1905c
- TIGR:   MT1956
- TubercuList:   Rv1905c
- GeneTree:   EBGT00050000015581
- HOGENOM:   HBG735740
- OMA:   AGFWQPY
- ProtClustDB:   CLSK871982
- GO:   GO:0005488
- InterPro:   IPR023209
- InterPro:   IPR006076
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000189

Pfam domain/function: PF01266 DAO

EC number: =1.4.3.3

Molecular weight: Translated: 34109; Mature: 33977

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00677 DAO

Important sites: BINDING 159-159 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVA
CCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCHHH
KVRGWIEQSLHVFRDLAKDPATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVP
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC
GGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEAAPIVINCAGLGA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCH
RELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDP
HHHCCCCCCCCCCCCEEEEECCCHHHEEEEECCCCCEEEEEECCCEEEECCCCCCCCCCC
TPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCC
DGVTLSWGCAREVVNLVGGG
CCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIGEQQVIVIGAGVSGLTSAICLAEAGWPVRVWAAALPQQTTSAVAGAVWGPRPKEPVA
CCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCHHH
KVRGWIEQSLHVFRDLAKDPATGVRMTPALSVGDRIETGAMPPGLELIPDVRPADPADVP
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC
GGFRAGFHATLPMIDMPQYLDCLTQRLAATGCEIETRPLRSLAEAAEAAPIVINCAGLGA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCH
RELAGDATVWPRFGQHVVLTNPGLEQLFIERTGGSEWICYFAHPQRVVCGGISIPGRWDP
HHHCCCCCCCCCCCCEEEEECCCHHHEEEEECCCCCEEEEEECCCEEEECCCCCCCCCCC
TPEPEITERILQRCRRIQPRLAEAAVIETITGLRPDRPSVRVEAEPIGRALCIHNYGHGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCC
DGVTLSWGCAREVVNLVGGG
CCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036