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The map label for this gene is insK [C]

Identifier: 148822539

GI number: 148822539

Start: 1485775

End: 1486611

Strand: Direct

Name: insK [C]

Synonym: TBFG_11348

Alternate gene names: 148822539

Gene position: 1485775-1486611 (Clockwise)

Preceding gene: 148822538

Following gene: 148822543

Centisome position: 33.58

GC content: 63.92

Gene sequence:

>837_bases
GTGCCGATCGCCCCATCGACCTACTACGACCACATCAACCGGGAGCCCAGCCGCCGCGAGCTGCGCGATGGCGAACTCAA
GGAGCACATCAGCCGCGTCCACGCCGCCAACTACGGTGTTTACGGTGCCCGCAAAGTGTGGCTAACCCTGAACCGTGAGG
GCATCGAGGTGGCCAGATGCACCGTCGAACGGCTGATGACCAAACTCGGCCTGTCCGGGACCACCCGCGGCAAAGCCCGC
AGGACCACGATCGCTGATCCGGCCACAGCCCGTCCCGCCGATCTCGTCCAGCGCCGCTTCGGACCACCAGCACCTAACCG
GCTGTGGGTAGCAGACCTCACCTATGTGTCGACCTGGGCAGGGTTCGCCTACGTGGCCTTTGTCACCGACGCCTACGCTC
GCAGGATCCTGGGCTGGCGGGTCGCTTCCACGATGGCCACCTCCATGGTCCTCGACGCGATCGAGCAAGCCATCTGGACC
CGCCAACAAGAAGGCGTACTCGACCTGAAAGACGTTATCCACCATACGGATAGGGGATCTCAGTACACATCGATCCGGTT
CAGCGAGCGGCTCGCCGAGGCAGGCATCCAACCGTCGGTCGGAGCGGTCGGAAGCTCCTATGACAATGCACTAGCCGAGA
CGATCAACGGCCTATACAAGACCGAGCTGATCAAACCCGGCAAGCCCTGGCGGTCCATCGAGGATGTCGAGTTGGCCACC
GCGCGCTGGGTCGACTGGTTCAACCATCGCCGCCTCTACCAGTACTGCGGCGACGTCCCGCCGGTCGAACTCGAGGCTGC
CTACTACGCTCAACGCCAGAGACCAGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
AATTACCCGGTTCATCGCCGATCATCAGGGCCACCGCGAGGGCCCCGATGGTTTGCGGTGGGGTGTCGAGTCGATCTGCA
CACAGCTGACCGAGCTGGGT

Downstream 100 bases:

>100_bases
GGTCTCAGATCAGAGAGTCTCCGGACTCACCGGGGCGGTTCAGGCCGTTGACCATCGCGTTGAAACCACGCTGCAGCTCA
CCGAGTTCGGTGCCGTCGAA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKAR
RTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWT
RQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELAT
ARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG

Sequences:

>Translated_278_residues
MPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKAR
RTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWT
RQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELAT
ARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>Mature_277_residues
PIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARR
TTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTR
QQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATA
RWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG

Specific function: Involved in the transposition of the insertion sequence

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain

Homologues:

Organism=Homo sapiens, GI310129419, Length=230, Percent_Identity=50.4347826086956, Blast_Score=226, Evalue=2e-59,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=27.3722627737226, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788405, Length=230, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787263, Length=230, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786753, Length=230, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786570, Length=230, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786490, Length=230, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRA9_MYCBO (P59800)

Other databases:

- EMBL:   BX248343
- RefSeq:   NP_856483.1
- ProteinModelPortal:   P59800
- SMR:   P59800
- EnsemblBacteria:   EBMYCT00000017289
- GeneID:   1092272
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2838c
- GeneTree:   EBGT00050000015373
- HOGENOM:   HBG757639
- OMA:   SIRFTER
- ProtClustDB:   CLSK790742
- BioCyc:   MBOV233413:MB2838C-MONOMER
- GO:   GO:0032196
- InterPro:   IPR001584
- InterPro:   IPR012337

Pfam domain/function: PF00665 rve; SSF53098 RNaseH_fold

EC number: NA

Molecular weight: Translated: 31369; Mature: 31238

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARC
CCCCCCHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
TVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
GFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELAT
CEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARC
CCCCCHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
TVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
GFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
QYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELAT
CEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972