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The map label for this gene is PE_PGRS20

Identifier: 148822277

GI number: 148822277

Start: 1194527

End: 1195918

Strand: Reverse

Name: PE_PGRS20

Synonym: TBFG_11086

Alternate gene names: 148822277

Gene position: 1195918-1194527 (Counterclockwise)

Preceding gene: 148822278

Following gene: 148822276

Centisome position: 27.03

GC content: 75.29

Gene sequence:

>1392_bases
ATGTCCTACATGATTGCGGTGCCAGACATGCTCAGCTCGGCGGCTGGGGATTTGGCCAGCATCGGATCGTCGATCAATGC
CTCAACGAGGGCGGCCGCGGCCGCGACGACGAGGTTGTTGCCGGCCGCCGCCGACGAAGTGTCGGCCCACATTGCGGCAC
TGTTTAGCGGACATGGCGAGGGCTATCAGGCGATCGCCCGGCAGATGGCAGCGTTTCATGACCAGTTCACGCTGGCCCTG
ACGTCAAGTGCGGGCGCGTATGCCAGCGCCGAGGCGACCAACGTCGAACAGCAGGTGCTGGGTTTGATCAACGCGCCCAC
CCAGGCGCTGTTGGGGCGTCCGCTGATCGGCAACGGCGCCGATGGGACCGCGGCCAATCCCAACGGTGGCGCCGGTGGGT
TGTTGTACGGCAACGGCGGCAACGGGTTTTCCCAAACCACCGCCGGGCTCACCGGGGGTACCGGCGGGTCGGCCGGGTTG
ATCGGCAACGGCGGCAACGGAGGGGCCGGCGGAGCCGGCGCCAACGGCGGCGCGGGCGGCAACGGCGGCTGGCTCTACGG
CAGCGGCGGCAATGGCGGCGCCGGCGGCGCCGGCCCCGCCGGAGCCATCGGCGCGCCGGGCGTCGCGGGTGGTGCCGGCG
GGGCCGGGGGAACGGCCGGATTGTTCGGCAACGGCGGTGCCGGCGGTGCCGGCGGAGCGGGCGGCGCCGGCGGCCGCGGT
GGCGACGGCGGGTCGGCCGGCTGGCTGTCCGGCAACGGCGGCGACGCCGGCACCGGCGGCGGCGGCGGCAACGCCGGCAA
CGGCGGCAACGGCGGGTCAGCCGGCTGGCTGTCGGGCAACGGCGGCACCGGCGGAGGCGGCGGCACCGCCGGCGCCGGCG
GCCAAGGCGGCAACGGCAACAGCGGTATTGATCCCGGTAACGGCGGCCAGGGCGCAGACACCGGCAACGCCGGCAACGGC
GGCCACGGCGGATCGGCCGCCAAGCTGTTCGGCGACGGCGGCGCCGGCGGCGCCGGTGGGATGGGCAGCACCGGCGGCAC
CGGCGGTGGCGGCGGCTTCGGCGGCGGCACCGGCGGCAACGGTGGCAACGGCCACGCGGGCGGTGCCGGCGGTAGCGGCG
GCACCGCCGGCCTGCTCGGCAGCGGAGGCAGCGGCGGCACCGGCGGCGACGGCGGCAACGGCGGTCTGGGCGCCGGCAGC
GGCGCCAAAGGCAACGGCGGCAACGGTGGCGACGGCGGCAAGGGCGGCGACGCCCAGTTGATCGGTAACGGCGGTAACGG
CGGCAACGGTGGCAAAGGCGGCACCGGCCTGATGCCCGGAATCAACGGCACTGGAGGCGCCGGCGGTAGTCGCGGGCAGA
TCTCCGGCAACCCCGGCACGCCCGGGCAATAA

Upstream 100 bases:

>100_bases
CGAACACTCTGCATTTCCGTTCCGGGCGTGCTTAGACTCGCGCCATCACGTTGACTCCGGTCCCGATATCCGTCGCCCGG
CGATGAGGGAGATGCGCGAA

Downstream 100 bases:

>100_bases
ACCCGCACGGCCAGATCCGGTGTGACGACGTATCACACAACGACGAGTGGCTTATGTCCAAGTATTTGACGTCGCCGGGT
GGCGCGAAAGATCACCCAAT

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHDQFTLAL
TSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGL
IGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRG
GDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNG
GHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGS
GAKGNGGNGGDGGKGGDAQLIGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ

Sequences:

>Translated_463_residues
MSYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHDQFTLAL
TSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGL
IGNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRG
GDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNG
GHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGS
GAKGNGGNGGDGGKGGDAQLIGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ
>Mature_462_residues
SYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHDQFTLALT
SSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGADGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLI
GNGGNGGAGGAGANGGAGGNGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRGG
DGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGNSGIDPGNGGQGADTGNAGNGG
HGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGNGGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSG
AKGNGGNGGDGGKGGDAQLIGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PG20_MYCTU (O53416)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   B70893
- RefSeq:   NP_335539.1
- RefSeq:   YP_177781.1
- ProteinModelPortal:   O53416
- EnsemblBacteria:   EBMYCT00000003070
- EnsemblBacteria:   EBMYCT00000070189
- GeneID:   887123
- GeneID:   925087
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1097
- KEGG:   mtu:Rv1068c
- TIGR:   MT1097
- TubercuList:   Rv1068c
- GeneTree:   EBGT00070000031715
- HOGENOM:   HBG131148
- OMA:   TATFTNS
- ProtClustDB:   CLSK799774
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 39306; Mature: 39175

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGE
CCEEEECHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GYQAIARQMAAFHDQFTLALTSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGA
HHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCHHHHHCCCCCCCCC
DGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGG
CCCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
NGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
SGIDPGNGGQGADTGNAGNGGHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGN
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSGAKGNGGNGGDGGKGGDAQL
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
IGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure 
SYMIAVPDMLSSAAGDLASIGSSINASTRAAAAATTRLLPAAADEVSAHIAALFSGHGE
CEEEECHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GYQAIARQMAAFHDQFTLALTSSAGAYASAEATNVEQQVLGLINAPTQALLGRPLIGNGA
HHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHCCHHHHHHHHHCCCHHHHHCCCCCCCCC
DGTAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIGNGGNGGAGGAGANGGAGG
CCCCCCCCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
NGGWLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTAGLFGNGGAGGAGGAGGAGGRG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDGGSAGWLSGNGGDAGTGGGGGNAGNGGNGGSAGWLSGNGGTGGGGGTAGAGGQGGNGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCC
SGIDPGNGGQGADTGNAGNGGHGGSAAKLFGDGGAGGAGGMGSTGGTGGGGGFGGGTGGN
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGNGHAGGAGGSGGTAGLLGSGGSGGTGGDGGNGGLGAGSGAKGNGGNGGDGGKGGDAQL
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
IGNGGNGGNGGKGGTGLMPGINGTGGAGGSRGQISGNPGTPGQ
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036