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The map label for this gene is fbpA [H]

Identifier: 148822155

GI number: 148822155

Start: 1060612

End: 1060896

Strand: Reverse

Name: fbpA [H]

Synonym: TBFG_10964

Alternate gene names: 148822155

Gene position: 1060896-1060612 (Counterclockwise)

Preceding gene: 148822156

Following gene: 148822154

Centisome position: 23.98

GC content: 67.72

Gene sequence:

>285_bases
ATGCCGCGAAGCTGGTGGCCAACAGCACCCCGTATCTGGGCGTATTCGGGCAACGGCACGCCCTCGGCGGAGTTGAGCGG
CAATAGGCGACAGGCTTTGCAAAGCAAGTACCAAGCGGCGCAACGGCGGTTCAACTTCCCGGATGGCGAAACCCACACCT
GGGCGTACTGGCGTGCGCCATTGCAGGCCATGCTGCCTGATCTGCAGCGGGTGCTGGGCGACGGTCAGCGGCCTCGGCGG
GGGCCGAGGCCGCGAGAGCGCAGGCCCGCATCGCCGAGCCTGTAG

Upstream 100 bases:

>100_bases
GGATCATCCCGAGTGGAAATGGCGTGGTTGCCGGATCCGCGTCATTGATCCGGGGGCCCGCCGACCGATCCGGCGTGGGC
CCACAGCGAGCCAACGGTCA

Downstream 100 bases:

>100_bases
ATACCGCGACAAACGGCGAGTGCCGCCGAGCACGATAACTAAAGGCTCGGCGAAGACAGCGGCTCTGATCGACGCCACTC
CACGGCATTAGGGTCGAACC

Product: hypothetical protein

Products: NA

Alternate protein names: Antigen 85 complex A; 85A; Ag85A; Fibronectin-binding protein A; Mycolyl transferase 85A [H]

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MPRSWWPTAPRIWAYSGNGTPSAELSGNRRQALQSKYQAAQRRFNFPDGETHTWAYWRAPLQAMLPDLQRVLGDGQRPRR
GPRPRERRPASPSL

Sequences:

>Translated_94_residues
MPRSWWPTAPRIWAYSGNGTPSAELSGNRRQALQSKYQAAQRRFNFPDGETHTWAYWRAPLQAMLPDLQRVLGDGQRPRR
GPRPRERRPASPSL
>Mature_93_residues
PRSWWPTAPRIWAYSGNGTPSAELSGNRRQALQSKYQAAQRRFNFPDGETHTWAYWRAPLQAMLPDLQRVLGDGQRPRRG
PRPRERRPASPSL

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 10869; Mature: 10738

Theoretical pI: Translated: 12.21; Mature: 12.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSWWPTAPRIWAYSGNGTPSAELSGNRRQALQSKYQAAQRRFNFPDGETHTWAYWRAP
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
LQAMLPDLQRVLGDGQRPRRGPRPRERRPASPSL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRSWWPTAPRIWAYSGNGTPSAELSGNRRQALQSKYQAAQRRFNFPDGETHTWAYWRAP
CCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
LQAMLPDLQRVLGDGQRPRRGPRPRERRPASPSL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7725062; 12788972 [H]