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The map label for this gene is PE_PGRS3 [H]

Identifier: 148821474

GI number: 148821474

Start: 333754

End: 335433

Strand: Reverse

Name: PE_PGRS3 [H]

Synonym: TBFG_10283

Alternate gene names: 148821474

Gene position: 335433-333754 (Counterclockwise)

Preceding gene: 148821475

Following gene: 148821473

Centisome position: 7.58

GC content: 76.49

Gene sequence:

>1680_bases
ATGTTCTTCGGCTCCGGCGGCGCCGGCGGCGCCGGCGGGTTCGGCCGCACCACCGGCGGGATAGGAGGCACCGGCGGCAA
CGCCGGCCTGCTCAACGGCTCCGGCGGCGCCGGCGGCGCCGGCGGCGCTGCTATCACCGGTCCAGGCGGCACCGGCGGGG
CCGGTGGCATACCCGGTTTGATCGGCAACGGCGGCAACGGCGGTGACGGCGGCGCCAGCGTGACCGGCACCGGCGGCAAC
GGCGGAGCGGGCGGTAACGGCGTGCAGATCGGCAACGGCGGCAACGGCGGCAGCGGCGGGACCGGCGCAGCCGCGGGCAA
GGCCGGCCTCGGCGGCCTCGGCGGGCAGCTAATAGGACTAGACGGATCCAATGCTCCAGTCAGCACCTCAGTCCATACCC
TGCAGCAGGCAGCGCTCAATGTGGTGAATGAGCCCTTCCAGACATTGACTGGGCGTCCGCTGATCGGCAACGGCGCCAAC
GGGACCCCGGGGACCGGGGCTGCCGGCGGGGCCGGCGGGTGGTTGTTCGGCAACGGCGGTAACGGCGGGCACGGTGCGAC
CAACACCGCCGCCACGGCTACGGGCGGGGCCGGCGGGGCCGGCGGGATCTTGTTCGGTACCGGTGGCAATGGCGGGACCG
GCGGGATAGCCACCGGTGCTGGAGGGATCGGCGGGGCCGGCGGCGCCGGTGGGGTCTCCTTGCTGATCGGCTCCGGCGGC
ACCGGCGGCAACGGTGGGAACTCCATAGGCGTCGCTGGCATCGGCGGGGCCGGCGGGCGCGGCGGCGACGCCGGTTTGCT
CTTCGGCGCGGCCGGCACCGGCGGCCACGGCGCCGCTGGCGGTGTCCCGGCCGGCGTCGGCGGCGCCGGCGGCAACGGCG
GACTGTTCGCCAACGGCGGAGCCGGAGGGGCCGGCGGGTTCAACGCAGCCGGCGGGAACGGCGGGAACGGCGGACTGTTC
GGAACTGGCGGCACCGGCGGGGCCGGCACGAACTTCGGGGCCGGTGGGAACGGCGGGAACGGCGGACTGTTCGGAGCCGG
CGGCACCGGCGGCGCCGCCGGCTCGGGAGGGTCCGGGATCACCACCGGCGGCGGCGGGCACGGCGGCAACGCCGGCCTAC
TCTCCCTCGGCGCCTCCGGTGGCGCCGGCGGCAGCGGTGGCGCCAGCTCCCTTGCCGGCGGGGCCGGCGGAACCGGCGGG
AACGGCGCCTTACTCTTCGGCTTCGGCGGCGCCGGCGGCGCCGGCGGGCACGGCGGGGCAGCACTTACCAGCATCCAGCA
AGGCGGCGCCGGCGGCGCCGGCGGGAACGGCGGCTTGCTCTTCGGCTCCGCCGGCGCCGGCGGCGCCGGCGGCAGCGGTG
CCAACGCTCTAGGCGCCGGTACCGGCGGCACCGGCGGTGACGGTGGCCACGCCGGGGTGTTCGGCAACGGCGGTGACGGG
GGTTGCCGGCGGGTTTGGCGCCGGTACCGGCGGCAGCGGTGGTGTCGGCGGCAACGCCGTGCTGATCGGCAACGGCGGCA
ACGGCGGCAACGCCGGCAAAGCCGGGGCCACGCCCGGTGCCGGCGGCACCGGCGGGCTGCTGCTCGGCGAGAACGGACTC
AACGGCTTGCCATAGCAGGCAGACCTGCGACCACACGCGGCGTTGAGGGCATCAGTTGCTCACCGCAGATGATGCCGTAG

Upstream 100 bases:

>100_bases
CACCGGCGGCAGTGGTGGGGGCGGCGCTACCACCGGCGGGGAAGGCCTTGCCAGCGCCGGCGGGGACGGCGGGGCCGGCG
GGGACGGCGGCAACGCGGGC

Downstream 100 bases:

>100_bases
ATGCGCTATCCTGAGCATCATGCGCACCACCGTGTCAATCTCGGATGAACTACTGGCTACCGCCAAACGCCGGGCCCGCG
AGCGTGGTTAATCGCTGGGC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGLIGNGGNGGDGGASVTGTGGN
GGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGAN
GTPGTGAAGGAGGWLFGNGGNGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGG
TGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFNAAGGNGGNGGLF
GTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGITTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGG
NGALLFGFGGAGGAGGHGGAALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDG
GCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAGRPATTRGVEGISCSPQMMP

Sequences:

>Translated_559_residues
MFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGLIGNGGNGGDGGASVTGTGGN
GGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGAN
GTPGTGAAGGAGGWLFGNGGNGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGG
TGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFNAAGGNGGNGGLF
GTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGITTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGG
NGALLFGFGGAGGAGGHGGAALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDG
GCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAGRPATTRGVEGISCSPQMMP
>Mature_559_residues
MFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGLIGNGGNGGDGGASVTGTGGN
GGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGAN
GTPGTGAAGGAGGWLFGNGGNGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGG
TGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFNAAGGNGGNGGLF
GTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGITTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGG
NGALLFGFGGAGGAGGHGGAALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDG
GCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAGRPATTRGVEGISCSPQMMP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 48704; Mature: 48704

Theoretical pI: Translated: 12.58; Mature: 12.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCC
IGNGGNGGDGGASVTGTGGNGGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGL
CCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
DGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGANGTPGTGAAGGAGGWLFGNGG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEECCC
NGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
TGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGG
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
AGGAGGFNAAGGNGGNGGLFGTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
TTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGGNGALLFGFGGAGGAGGHGGA
CCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCH
ALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDG
HHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
GCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RPATTRGVEGISCSPQMMP
CCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCC
IGNGGNGGDGGASVTGTGGNGGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGL
CCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
DGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGANGTPGTGAAGGAGGWLFGNGG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEECCC
NGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
TGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGG
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
AGGAGGFNAAGGNGGNGGLFGTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
TTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGTGGNGALLFGFGGAGGAGGHGGA
CCCCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCH
ALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDG
HHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
GCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
RPATTRGVEGISCSPQMMP
CCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]