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The map label for this gene is ppe28 [H]

Identifier: 148821351

GI number: 148821351

Start: 187749

End: 189155

Strand: Reverse

Name: ppe28 [H]

Synonym: TBFG_10160

Alternate gene names: 148821351

Gene position: 189155-187749 (Counterclockwise)

Preceding gene: 148821352

Following gene: 148821346

Centisome position: 4.28

GC content: 62.69

Gene sequence:

>1407_bases
ATGTCCTACGTCATCGCGGCCCCGGAGATGTTGGCAACGGCGGCCGCGGACGTGGACGGGATCGGTTCGGCGATACGAGC
GGCCAGCGCGTCCGCTGCGGGTCCAACGACCGGACTGCTGGCCGCGGCCGCCGATGAGGTGTCGTCGGCCGCTGCAGCGC
TGTTCAGCGAATACGCGCGCGAATGTCAAGAGGTCCTAAAGCAGGCTGCGGCGTTCCATGGCGAGTTCACCCGGGCGCTG
GCTGCCGCCGGGGCCGCCTATGCCCAGGCTGAAGCCAGCAACACCGCTGCTATGTCGGGCACCGCCGGGTCCAGCGGCGC
CCTCGGTTCTGTCGGGATGCTGTCAGGCAACCCGCTAACCGCGTTGATGATGGGCGGCACCGGGGAACCGATCCTTAGTG
ACCGCGTCTTGGCGATCATTGACAGCGCATACATTCGGCCCATTTTCGGGCCCAACAACCCGGTCGCCCAGTACACGCCC
GAGCAGTGGTGGCCGTTTATCGGGAACCTGTCACTGGACCAATCCATCGCCCAGGGTGTCACGCTGCTGAACAACGGCAT
CAACGCGGAACTACAAAATGGGCATGACGTCGTCGTTTTCGGCTACTCGCAAAGCGCCGCGGTAGCGACCAATGAAATAC
GCGCTCTTATGGCGTTACCACCGGGCCAAGCCCCAGATCCAAGCCGGCTGGCTTTCACGTTGATCGGTAATATCAATAAC
CCCAACGGCGGCGTCCTCGAGCGTTACGTGGGCCTTTACCTCCCGTTCTTGGATATGTCGTTCAACGGTGCGACTCCACC
GGATTCCCCCTACCAGACCTACATGTACACCGGCCAATACGACGGCTACGCCCACAACCCGCAGTACCCGCTCAATATCT
TGTCGGACCTCAACGCCTTCATGGGCATCAGATGGGTGCACAACGCGTACCCCTTCACCGCGGCCGAGGTTGCCAATGCC
GTGCCGTTGCCCACGTCTCCGGGCTACACCGGCAACACCCATTACTACATGTTTCTGACCCAGGACCTGCCGCTGTTGCA
GCCGATTCGCGCCATCCCCTTCGTAGGGACCCCAATAGCCGAGCTGATTCAGCCCGACCTACGGGTGCTAGTCGACTTGG
GCTATGGCTACGGCTACGCCGACGTACCCACCCCGGCCAGCCTGTTCGCGCCAATCAACCCGATCGCCGTGGCCTCGGCC
CTGGCGACCGGGACCGTGCAAGGCCCCCAAGCCGCCCTAGTAAGCATCGGATTGTTACCGCAGTCCGCGCTACCCAATAC
GTATCCGTATCTTCCGTCGGCGAATCCGGGCCTGATGTTCAACTTCGGTCAATCCAGTGTGACGGAGTTGTCGGTGCTCA
GTGGCGCCCTCGGGTCCGTAGCGAGATTGATTCCACCGATCGCGTGA

Upstream 100 bases:

>100_bases
TTCACCTGACGCGGCCGCGATAACGATTGGCCGAAAACGCCGGGCTTCCCGGCGGGCGCGCTCTAGGCTCTAAGGGCCCC
AGCGTCGAACAGGAGACCAG

Downstream 100 bases:

>100_bases
GGTTCACGTTTCCTTCCGAGTTCCAAGCGGAGACTGGTTGCGGATCGATTCGTCGCGGATCAGCCCGCGCAGCAGTGCCG
TGCTGAACTCCGCCGCGATC

Product: PE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRAL
AAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTP
EQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINN
PNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANA
VPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASA
LATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA

Sequences:

>Translated_468_residues
MSYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRAL
AAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTP
EQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINN
PNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANA
VPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASA
LATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA
>Mature_467_residues
SYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRALA
AAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTPE
QWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINNP
NGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANAV
PLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASAL
ATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 48578; Mature: 48447

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYAR
CCEEEECHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEECCCCEE
ALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTPEQWWPFIGNLSLDQSIAQGV
EEEECCCCCCHHHCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
TLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINN
HHHCCCCCCEECCCCEEEEEECCCCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCC
PNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
MGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIA
HHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCHH
ELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASALATGTVQGPQAALVSIGLLP
HHHCHHHHEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHHEEECCC
QSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA
CCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SYVIAAPEMLATAAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYAR
CEEEECHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEECCCCEE
ALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTPEQWWPFIGNLSLDQSIAQGV
EEEECCCCCCHHHCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
TLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINN
HHHCCCCCCEECCCCEEEEEECCCCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCC
PNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
MGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIA
HHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCHH
ELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASALATGTVQGPQAALVSIGLLP
HHHCHHHHEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHHEEECCC
QSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA
CCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]