| Definition | Mycobacterium tuberculosis H37Ra, complete genome. |
|---|---|
| Accession | NC_009525 |
| Length | 4,419,977 |
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The map label for this gene is ftsH
Identifier: 148663474
GI number: 148663474
Start: 4059266
End: 4061548
Strand: Reverse
Name: ftsH
Synonym: MRA_3649
Alternate gene names: 148663474
Gene position: 4061548-4059266 (Counterclockwise)
Preceding gene: 148663475
Following gene: 148663473
Centisome position: 91.89
GC content: 65.79
Gene sequence:
>2283_bases ATGAACCGGAAAAACGTGACTCGCACCATAACAGCGATCGCCGTCGTGGTGCTGCTCGGCTGGTCGTTCTTTTACTTCAG CGACGACACCCGCGGCTACAAGCCCGTTGATACCTCGGTGGCGATAACACAGATCAACGGCGACAACGTCAAGAGCGCAC AGATCGACGATCGCGAGCAACAGCTGCGGCTGATCCTGAAGAAGGGTAACAACGAGACCGACGGGTCCGAGAAGGTCATC ACCAAGTACCCCACCGGGTACGCCGTCGACCTGTTCAACGCGCTCAGCGCCAAAAACGCGAAGGTCAGCACGGTCGTCAA CCAGGGCAGCATCCTGGGCGAGCTGCTGGTCTACGTGCTGCCGCTGCTGTTGCTGGTGGGGCTGTTCGTGATGTTCTCCC GCATGCAAGGCGGCGCCCGGATGGGCTTCGGGTTCGGCAAGTCACGCGCCAAGCAACTGAGCAAGGACATGCCCAAGACC ACCTTCGCCGACGTCGCAGGTGTCGACGAGGCGGTCGAGGAGCTCTACGAGATCAAGGACTTCCTGCAGAACCCCAGCAG GTACCAAGCGCTGGGCGCCAAGATCCCCAAAGGCGTGCTGCTCTACGGGCCGCCGGGAACCGGTAAGACGTTGCTGGCTC GTGCGGTGGCCGGCGAAGCCGGAGTGCCGTTCTTCACCATCTCCGGCTCCGACTTCGTCGAAATGTTCGTCGGCGTCGGC GCATCCCGTGTCAGAGACCTGTTCGAGCAGGCCAAGCAGAACAGCCCGTGCATCATCTTCGTCGACGAGATCGACGCCGT CGGCCGACAAAGAGGCGCCGGGCTGGGCGGCGGTCACGACGAGCGTGAGCAGACCCTCAACCAGTTGCTAGTCGAAATGG ACGGTTTTGGCGATCGCGCCGGCGTCATCCTGATCGCGGCCACCAACCGGCCCGACATCCTGGACCCGGCGCTGTTGCGG CCGGGCCGCTTCGACCGCCAGATCCCGGTATCCAACCCCGATCTGGCGGGTCGGCGGGCGGTGCTGCGCGTGCACTCCAA GGGCAAGCCGATGGCCGCGGACGCCGACCTCGACGGACTGGCCAAGCGGACCGTCGGCATGACCGGAGCCGACCTGGCCA ACGTCATCAACGAGGCGGCGCTGCTGACCGCCCGGGAGAACGGCACCGTCATCACCGGTCCCGCCCTCGAGGAAGCGGTG GACCGGGTGATCGGCGGCCCGCGCCGCAAAGGCCGGATCATCAGCGAGCAGGAGAAGAAGATCACCGCCTATCACGAGGG CGGGCACACCCTGGCCGCTTGGGCGATGCCCGATATCGAGCCGATTTATAAGGTGACGATCCTGGCGCGCGGGCGTACCG GCGGGCACGCGGTGGCGGTGCCGGAAGAAGACAAGGGCCTGCGGACCCGCTCGGAAATGATCGCGCAACTGGTGTTCGCG ATGGGTGGGCGCGCCGCCGAAGAACTGGTGTTTCGTGAGCCGACCACCGGCGCGGTGTCCGACATCGAGCAGGCCACCAA GATAGCGCGCTCAATGGTCACCGAATTTGGAATGAGCTCCAAGCTGGGCGCGGTCAAATACGGCTCCGAACACGGCGACC CGTTCCTCGGACGTACCATGGGCACCCAGCCGGACTACTCCCACGAGGTCGCCCGCGAGATCGACGAAGAGGTCCGCAAG CTTATCGAGGCGGCGCATACCGAAGCGTGGGAAATCCTGACCGAATACCGCGACGTGCTGGACACTTTGGCCGGCGAGCT GCTGGAAAAGGAGACCCTGCACCGACCCGAGCTGGAAAGCATCTTCGCTGACGTCGAAAAGCGGCCGCGGCTCACCATGT TCGACGACTTCGGTGGCCGGATCCCGTCGGACAAACCGCCCATCAAGACACCCGGCGAGCTCGCGATCGAACGCGGCGAA CCTTGGCCCCAGCCGGTCCCCGAGCCGGCGTTCAAGGCGGCGATTGCGCAGGCTACCCAAGCCGCTGAGGCCGCCCGGTC CGACGCCGGCCAAACCGGGCACGGCGCCAACGGTTCGCCCGCCGGCACCCACCGGTCCGGTGACCGCCAGTACGGCTCCA CCCAGCCTGACTACGGTGCCCCGGCGGGCTGGCATGCGCCGGGATGGCCCCCAAGGTCATCTCATCGGCCCAGCTATAGC GGTGAACCGGCACCGACGTATCCGGGTCAGCCCTACCCGACCGGTCAAGCCGATCCGGGTTCCGATGAGTCCTCGGCGGA GCAGGATGACGAGGTCAGTCGGACCAAGCCGGCCCACGGCTGA
Upstream 100 bases:
>100_bases ACCCGGCTCTGGGGTGATTGCCTGGCTCCTCCTCGAGCGGTTTGCGGGCCTTTCCAGCTGCGTGTATCGGGAAGGACCTG GCCGGCACGGCCGATGATCG
Downstream 100 bases:
>100_bases CGAACGGAGCATTCGATGTCGCAGCTGGATTCGCGCAGCGCATCTGCTCGTATCCGTGTGTTCGACCAGCAACGTGCCGA GGCCGCGGTGCGCGAATTGC
Product: cell division protein FtsH
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 760; Mature: 760
Protein sequence:
>760_residues MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQQLRLILKKGNNETDGSEKVI TKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKT TFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLR PGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAV DRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDYSHEVAREIDEEVRK LIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGE PWPQPVPEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG
Sequences:
>Translated_760_residues MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQQLRLILKKGNNETDGSEKVI TKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKT TFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLR PGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAV DRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDYSHEVAREIDEEVRK LIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGE PWPQPVPEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG >Mature_760_residues MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQQLRLILKKGNNETDGSEKVI TKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKT TFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLR PGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAV DRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDYSHEVAREIDEEVRK LIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGE PWPQPVPEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family
Homologues:
Organism=Homo sapiens, GI300192933, Length=502, Percent_Identity=46.8127490039841, Blast_Score=436, Evalue=1e-122, Organism=Homo sapiens, GI21327685, Length=486, Percent_Identity=45.0617283950617, Blast_Score=391, Evalue=1e-108, Organism=Homo sapiens, GI7657689, Length=486, Percent_Identity=45.0617283950617, Blast_Score=390, Evalue=1e-108, Organism=Homo sapiens, GI4507173, Length=447, Percent_Identity=43.6241610738255, Blast_Score=365, Evalue=1e-101, Organism=Homo sapiens, GI4506209, Length=248, Percent_Identity=43.5483870967742, Blast_Score=212, Evalue=1e-54, Organism=Homo sapiens, GI24497435, Length=253, Percent_Identity=41.501976284585, Blast_Score=203, Evalue=4e-52, Organism=Homo sapiens, GI24430151, Length=248, Percent_Identity=39.9193548387097, Blast_Score=203, Evalue=5e-52, Organism=Homo sapiens, GI6005942, Length=231, Percent_Identity=44.5887445887446, Blast_Score=197, Evalue=3e-50, Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=40.8163265306122, Blast_Score=196, Evalue=6e-50, Organism=Homo sapiens, GI21361144, Length=247, Percent_Identity=41.7004048582996, Blast_Score=195, Evalue=2e-49, Organism=Homo sapiens, GI89064750, Length=252, Percent_Identity=39.2857142857143, Blast_Score=192, Evalue=1e-48, Organism=Homo sapiens, GI5729991, Length=252, Percent_Identity=39.2857142857143, Blast_Score=191, Evalue=2e-48, Organism=Homo sapiens, GI24430155, Length=252, Percent_Identity=39.2857142857143, Blast_Score=191, Evalue=3e-48, Organism=Homo sapiens, GI45643123, Length=278, Percent_Identity=39.568345323741, Blast_Score=191, Evalue=3e-48, Organism=Homo sapiens, GI45643125, Length=278, Percent_Identity=39.568345323741, Blast_Score=190, Evalue=4e-48, Organism=Homo sapiens, GI157671927, Length=241, Percent_Identity=39.8340248962656, Blast_Score=185, Evalue=1e-46, Organism=Homo sapiens, GI229577436, Length=253, Percent_Identity=39.5256916996047, Blast_Score=173, Evalue=7e-43, Organism=Homo sapiens, GI4505725, Length=215, Percent_Identity=40.9302325581395, Blast_Score=166, Evalue=5e-41, Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=57.6642335766423, Blast_Score=166, Evalue=9e-41, Organism=Homo sapiens, GI24497618, Length=231, Percent_Identity=40.2597402597403, Blast_Score=164, Evalue=2e-40, Organism=Homo sapiens, GI153792536, Length=231, Percent_Identity=39.3939393939394, Blast_Score=162, Evalue=1e-39, Organism=Homo sapiens, GI194018488, Length=227, Percent_Identity=40.0881057268723, Blast_Score=144, Evalue=2e-34, Organism=Homo sapiens, GI5901990, Length=255, Percent_Identity=36.4705882352941, Blast_Score=142, Evalue=2e-33, Organism=Homo sapiens, GI14149767, Length=263, Percent_Identity=34.2205323193916, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI62177112, Length=263, Percent_Identity=34.2205323193916, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI226371754, Length=240, Percent_Identity=38.3333333333333, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=35.8333333333333, Blast_Score=136, Evalue=8e-32, Organism=Homo sapiens, GI17865802, Length=240, Percent_Identity=36.25, Blast_Score=135, Evalue=2e-31, Organism=Homo sapiens, GI156564401, Length=274, Percent_Identity=33.5766423357664, Blast_Score=132, Evalue=9e-31, Organism=Homo sapiens, GI31742536, Length=228, Percent_Identity=32.8947368421053, Blast_Score=131, Evalue=3e-30, Organism=Homo sapiens, GI112789543, Length=228, Percent_Identity=32.8947368421053, Blast_Score=131, Evalue=3e-30, Organism=Homo sapiens, GI310125282, Length=274, Percent_Identity=33.2116788321168, Blast_Score=129, Evalue=8e-30, Organism=Homo sapiens, GI31377644, Length=236, Percent_Identity=35.5932203389831, Blast_Score=129, Evalue=8e-30, Organism=Homo sapiens, GI310125280, Length=211, Percent_Identity=37.914691943128, Blast_Score=127, Evalue=4e-29, Organism=Homo sapiens, GI11875211, Length=234, Percent_Identity=39.3162393162393, Blast_Score=127, Evalue=4e-29, Organism=Homo sapiens, GI40806170, Length=234, Percent_Identity=39.3162393162393, Blast_Score=127, Evalue=5e-29, Organism=Homo sapiens, GI64084766, Length=229, Percent_Identity=28.3842794759825, Blast_Score=97, Evalue=4e-20, Organism=Homo sapiens, GI75677353, Length=270, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-13, Organism=Homo sapiens, GI116292174, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI4757852, Length=158, Percent_Identity=31.6455696202532, Blast_Score=68, Evalue=3e-11, Organism=Homo sapiens, GI119964730, Length=158, Percent_Identity=31.6455696202532, Blast_Score=68, Evalue=3e-11, Organism=Escherichia coli, GI1789568, Length=605, Percent_Identity=49.0909090909091, Blast_Score=560, Evalue=1e-160, Organism=Caenorhabditis elegans, GI71994521, Length=469, Percent_Identity=47.9744136460554, Blast_Score=410, Evalue=1e-114, Organism=Caenorhabditis elegans, GI17554264, Length=446, Percent_Identity=46.6367713004484, Blast_Score=374, Evalue=1e-103, Organism=Caenorhabditis elegans, GI115534323, Length=456, Percent_Identity=41.0087719298246, Blast_Score=337, Evalue=1e-92, Organism=Caenorhabditis elegans, GI17563248, Length=250, Percent_Identity=44.8, Blast_Score=217, Evalue=2e-56, Organism=Caenorhabditis elegans, GI17554786, Length=253, Percent_Identity=41.897233201581, Blast_Score=210, Evalue=3e-54, Organism=Caenorhabditis elegans, GI17532375, Length=249, Percent_Identity=40.5622489959839, Blast_Score=209, Evalue=3e-54, Organism=Caenorhabditis elegans, GI25144278, Length=253, Percent_Identity=42.2924901185771, Blast_Score=209, Evalue=6e-54, Organism=Caenorhabditis elegans, GI25144281, Length=253, Percent_Identity=42.2924901185771, Blast_Score=208, Evalue=9e-54, Organism=Caenorhabditis elegans, GI17563250, Length=248, Percent_Identity=39.5161290322581, Blast_Score=197, Evalue=2e-50, Organism=Caenorhabditis elegans, GI17531535, Length=250, Percent_Identity=41.2, Blast_Score=194, Evalue=2e-49, Organism=Caenorhabditis elegans, GI71987364, Length=250, Percent_Identity=40, Blast_Score=194, Evalue=2e-49, Organism=Caenorhabditis elegans, GI17505546, Length=248, Percent_Identity=40.7258064516129, Blast_Score=194, Evalue=2e-49, Organism=Caenorhabditis elegans, GI71987372, Length=250, Percent_Identity=40, Blast_Score=193, Evalue=2e-49, Organism=Caenorhabditis elegans, GI17508701, Length=255, Percent_Identity=39.6078431372549, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17554784, Length=248, Percent_Identity=41.1290322580645, Blast_Score=183, Evalue=3e-46, Organism=Caenorhabditis elegans, GI17508053, Length=261, Percent_Identity=40.2298850574713, Blast_Score=180, Evalue=2e-45, Organism=Caenorhabditis elegans, GI17537217, Length=279, Percent_Identity=38.7096774193548, Blast_Score=168, Evalue=1e-41, Organism=Caenorhabditis elegans, GI193206116, Length=234, Percent_Identity=41.4529914529915, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI133931034, Length=234, Percent_Identity=41.4529914529915, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI193206114, Length=234, Percent_Identity=41.4529914529915, Blast_Score=162, Evalue=5e-40, Organism=Caenorhabditis elegans, GI25153574, Length=262, Percent_Identity=33.969465648855, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI193209502, Length=260, Percent_Identity=33.8461538461538, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=35.7758620689655, Blast_Score=142, Evalue=7e-34, Organism=Caenorhabditis elegans, GI133901658, Length=278, Percent_Identity=33.0935251798561, Blast_Score=135, Evalue=7e-32, Organism=Caenorhabditis elegans, GI133901662, Length=275, Percent_Identity=33.4545454545455, Blast_Score=134, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=41.8181818181818, Blast_Score=132, Evalue=6e-31, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=41.8181818181818, Blast_Score=132, Evalue=6e-31, Organism=Caenorhabditis elegans, GI86561515, Length=234, Percent_Identity=34.6153846153846, Blast_Score=130, Evalue=3e-30, Organism=Caenorhabditis elegans, GI25146157, Length=229, Percent_Identity=37.5545851528384, Blast_Score=125, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17508421, Length=233, Percent_Identity=37.7682403433476, Blast_Score=124, Evalue=2e-28, Organism=Caenorhabditis elegans, GI32563584, Length=229, Percent_Identity=37.9912663755458, Blast_Score=124, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17541226, Length=244, Percent_Identity=34.0163934426229, Blast_Score=116, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17541224, Length=244, Percent_Identity=34.0163934426229, Blast_Score=116, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17560432, Length=234, Percent_Identity=33.7606837606838, Blast_Score=109, Evalue=7e-24, Organism=Caenorhabditis elegans, GI71990294, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6320854, Length=495, Percent_Identity=46.6666666666667, Blast_Score=432, Evalue=1e-121, Organism=Saccharomyces cerevisiae, GI6323736, Length=533, Percent_Identity=44.2776735459662, Blast_Score=429, Evalue=1e-121, Organism=Saccharomyces cerevisiae, GI6325281, Length=452, Percent_Identity=44.9115044247788, Blast_Score=364, Evalue=1e-101, Organism=Saccharomyces cerevisiae, GI6322704, Length=256, Percent_Identity=43.359375, Blast_Score=215, Evalue=2e-56, Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=41.3385826771654, Blast_Score=211, Evalue=5e-55, Organism=Saccharomyces cerevisiae, GI6320197, Length=248, Percent_Identity=39.9193548387097, Blast_Score=205, Evalue=2e-53, Organism=Saccharomyces cerevisiae, GI6320077, Length=238, Percent_Identity=44.1176470588235, Blast_Score=203, Evalue=1e-52, Organism=Saccharomyces cerevisiae, GI6324833, Length=254, Percent_Identity=41.3385826771654, Blast_Score=199, Evalue=2e-51, Organism=Saccharomyces cerevisiae, GI6320602, Length=244, Percent_Identity=43.0327868852459, Blast_Score=192, Evalue=1e-49, Organism=Saccharomyces cerevisiae, GI6324691, Length=270, Percent_Identity=38.8888888888889, Blast_Score=187, Evalue=6e-48, Organism=Saccharomyces cerevisiae, GI6322994, Length=234, Percent_Identity=36.3247863247863, Blast_Score=169, Evalue=1e-42, Organism=Saccharomyces cerevisiae, GI6321709, Length=257, Percent_Identity=37.7431906614786, Blast_Score=167, Evalue=7e-42, Organism=Saccharomyces cerevisiae, GI6323429, Length=242, Percent_Identity=38.4297520661157, Blast_Score=165, Evalue=3e-41, Organism=Saccharomyces cerevisiae, GI6324000, Length=230, Percent_Identity=39.5652173913043, Blast_Score=160, Evalue=1e-39, Organism=Saccharomyces cerevisiae, GI6322651, Length=264, Percent_Identity=35.9848484848485, Blast_Score=158, Evalue=3e-39, Organism=Saccharomyces cerevisiae, GI6325431, Length=234, Percent_Identity=38.8888888888889, Blast_Score=143, Evalue=1e-34, Organism=Saccharomyces cerevisiae, GI6319554, Length=244, Percent_Identity=34.0163934426229, Blast_Score=128, Evalue=3e-30, Organism=Saccharomyces cerevisiae, GI6321465, Length=229, Percent_Identity=36.2445414847162, Blast_Score=127, Evalue=7e-30, Organism=Saccharomyces cerevisiae, GI6325183, Length=245, Percent_Identity=33.469387755102, Blast_Score=117, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6320887, Length=253, Percent_Identity=33.9920948616601, Blast_Score=114, Evalue=5e-26, Organism=Saccharomyces cerevisiae, GI6320583, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI28574878, Length=608, Percent_Identity=41.1184210526316, Blast_Score=427, Evalue=1e-119, Organism=Drosophila melanogaster, GI24665814, Length=608, Percent_Identity=41.1184210526316, Blast_Score=426, Evalue=1e-119, Organism=Drosophila melanogaster, GI24658770, Length=546, Percent_Identity=41.5750915750916, Blast_Score=387, Evalue=1e-107, Organism=Drosophila melanogaster, GI24639391, Length=439, Percent_Identity=46.6970387243736, Blast_Score=385, Evalue=1e-107, Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=42.6294820717131, Blast_Score=208, Evalue=9e-54, Organism=Drosophila melanogaster, GI161076488, Length=232, Percent_Identity=39.6551724137931, Blast_Score=204, Evalue=3e-52, Organism=Drosophila melanogaster, GI17137560, Length=232, Percent_Identity=39.6551724137931, Blast_Score=204, Evalue=3e-52, Organism=Drosophila melanogaster, GI161076486, Length=232, Percent_Identity=39.6551724137931, Blast_Score=204, Evalue=3e-52, Organism=Drosophila melanogaster, GI19920408, Length=253, Percent_Identity=41.501976284585, Blast_Score=203, Evalue=4e-52, Organism=Drosophila melanogaster, GI24649446, Length=248, Percent_Identity=40.3225806451613, Blast_Score=202, Evalue=6e-52, Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=58.2822085889571, Blast_Score=202, Evalue=7e-52, Organism=Drosophila melanogaster, GI24651451, Length=253, Percent_Identity=41.1067193675889, Blast_Score=199, Evalue=9e-51, Organism=Drosophila melanogaster, GI17738151, Length=258, Percent_Identity=39.5348837209302, Blast_Score=196, Evalue=4e-50, Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=42.5531914893617, Blast_Score=195, Evalue=8e-50, Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=42.5531914893617, Blast_Score=195, Evalue=8e-50, Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=42.5531914893617, Blast_Score=195, Evalue=1e-49, Organism=Drosophila melanogaster, GI281361487, Length=242, Percent_Identity=40.495867768595, Blast_Score=190, Evalue=3e-48, Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.4081632653061, Blast_Score=189, Evalue=5e-48, Organism=Drosophila melanogaster, GI18860063, Length=242, Percent_Identity=40.0826446280992, Blast_Score=189, Evalue=7e-48, Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=37.6470588235294, Blast_Score=186, Evalue=4e-47, Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=43.1578947368421, Blast_Score=182, Evalue=6e-46, Organism=Drosophila melanogaster, GI19921202, Length=237, Percent_Identity=37.9746835443038, Blast_Score=176, Evalue=4e-44, Organism=Drosophila melanogaster, GI24656825, Length=224, Percent_Identity=40.1785714285714, Blast_Score=165, Evalue=1e-40, Organism=Drosophila melanogaster, GI24656820, Length=204, Percent_Identity=42.156862745098, Blast_Score=165, Evalue=1e-40, Organism=Drosophila melanogaster, GI281363136, Length=237, Percent_Identity=39.2405063291139, Blast_Score=161, Evalue=1e-39, Organism=Drosophila melanogaster, GI78707192, Length=237, Percent_Identity=39.2405063291139, Blast_Score=161, Evalue=1e-39, Organism=Drosophila melanogaster, GI21355121, Length=213, Percent_Identity=36.6197183098592, Blast_Score=146, Evalue=5e-35, Organism=Drosophila melanogaster, GI18859657, Length=249, Percent_Identity=36.9477911646586, Blast_Score=145, Evalue=9e-35, Organism=Drosophila melanogaster, GI24644145, Length=239, Percent_Identity=37.2384937238494, Blast_Score=138, Evalue=2e-32, Organism=Drosophila melanogaster, GI20129423, Length=236, Percent_Identity=33.8983050847458, Blast_Score=135, Evalue=1e-31, Organism=Drosophila melanogaster, GI28571849, Length=238, Percent_Identity=39.9159663865546, Blast_Score=133, Evalue=6e-31, Organism=Drosophila melanogaster, GI28571847, Length=238, Percent_Identity=39.9159663865546, Blast_Score=133, Evalue=6e-31, Organism=Drosophila melanogaster, GI20129529, Length=233, Percent_Identity=32.618025751073, Blast_Score=130, Evalue=3e-30, Organism=Drosophila melanogaster, GI28573010, Length=211, Percent_Identity=38.3886255924171, Blast_Score=129, Evalue=1e-29, Organism=Drosophila melanogaster, GI281360144, Length=259, Percent_Identity=32.4324324324324, Blast_Score=128, Evalue=2e-29, Organism=Drosophila melanogaster, GI281360140, Length=259, Percent_Identity=32.4324324324324, Blast_Score=128, Evalue=2e-29, Organism=Drosophila melanogaster, GI281360136, Length=259, Percent_Identity=32.4324324324324, Blast_Score=128, Evalue=2e-29, Organism=Drosophila melanogaster, GI24644411, Length=259, Percent_Identity=32.4324324324324, Blast_Score=128, Evalue=2e-29, Organism=Drosophila melanogaster, GI281360142, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29, Organism=Drosophila melanogaster, GI21357333, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29, Organism=Drosophila melanogaster, GI281360146, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29, Organism=Drosophila melanogaster, GI281360138, Length=259, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29, Organism=Drosophila melanogaster, GI17864540, Length=214, Percent_Identity=38.3177570093458, Blast_Score=127, Evalue=3e-29, Organism=Drosophila melanogaster, GI24581396, Length=234, Percent_Identity=33.7606837606838, Blast_Score=116, Evalue=7e-26, Organism=Drosophila melanogaster, GI24639486, Length=190, Percent_Identity=34.7368421052632, Blast_Score=100, Evalue=7e-21, Organism=Drosophila melanogaster, GI20129417, Length=152, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=2e-12, Organism=Drosophila melanogaster, GI24583262, Length=152, Percent_Identity=34.2105263157895, Blast_Score=72, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): FTSH_MYCBO (P0A4V9)
Other databases:
- EMBL: BX248346 - RefSeq: NP_857279.1 - ProteinModelPortal: P0A4V9 - MEROPS: M41.015 - EnsemblBacteria: EBMYCT00000015909 - GeneID: 1093562 - GenomeReviews: BX248333_GR - KEGG: mbo:Mb3640c - GeneTree: EBGT00050000014910 - HOGENOM: HBG724153 - OMA: DPFLGRS - ProtClustDB: CLSK792593 - BioCyc: MBOV233413:MB3640C-MONOMER - GO: GO:0006508 - HAMAP: MF_01458 - InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR000642 - SMART: SM00382 - TIGRFAMs: TIGR01241
Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41
EC number: 3.4.24.-
Molecular weight: Translated: 81986; Mature: 81986
Theoretical pI: Translated: 5.60; Mature: 5.60
Prosite motif: PS00674 AAA
Important sites: ACT_SITE 426-426
Signals:
None
Transmembrane regions:
HASH(0x21c92740)-; HASH(0x222ef6f8)-;
Cys/Met content:
0.1 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQ CCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH QLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVL HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHH PLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKD HHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH FLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG HHCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCC ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRA HHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC GVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGL CEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHH AKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAVDRVIGGPRRKGRIISEQEKK HHHHCCCCCHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCHHHE ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA EEEEECCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHH MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTM HCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCC GTQPDYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELES CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH IFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIAQATQ HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHH AAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCH >Mature Secondary Structure MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQ CCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH QLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVL HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHH PLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKD HHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH FLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG HHCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCC ASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRA HHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC GVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGL CEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHH AKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAVDRVIGGPRRKGRIISEQEKK HHHHCCCCCHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHCCCCCCCCCCCCHHHE ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFA EEEEECCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHH MGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTM HCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCC GTQPDYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELES CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH IFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIAQATQ HHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHH AAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYS HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC GEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCH
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12788972