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The map label for this gene is eccB4

Identifier: 148663315

GI number: 148663315

Start: 3879761

End: 3881173

Strand: Reverse

Name: eccB4

Synonym: MRA_3491

Alternate gene names: 148663315

Gene position: 3881173-3879761 (Counterclockwise)

Preceding gene: 148663320

Following gene: 148663312

Centisome position: 87.81

GC content: 70.13

Gene sequence:

>1413_bases
GTGCCGAGCCCAGCGACGACCTGGCTGCACGTCAGCGGGTACCGATTTCTGCTGCGGCGCATCGAGTGCGCGTTGCTGTT
CGGGGATGTCTGCGCAGCGACCGGAGCACTGCGCGCGCGCACAACATCGCTGGCCCTCGGGTGCGTGCTGGCGATCGTCG
CCGCGATGGGATGCGCATTCGTTGCGCTGCTGCGGCCACAGTCGGCGCTCGGTCAGGCGCCGATCGTGATGGGTCGGGAA
TCCGGGGCACTCTACGTGCGAGTGGACGATGTCTGGCATCCGGTGTTGAACCTGGCTTCGGCGCGGTTGATCGCGGCGAC
GAACGCCAACCCGCAACCGGTGTCCGAGTCCGAATTGGGCCACACCAAACGCGGTCCACTGCTCGGTATTCCAGGTGCGC
CGCAGCTGCTTGACCAGCCGCTAGCCGGCGCCGAATCGGCGTGGGCGATCTGCGATAGCGACAATGGCGGATCAACGACT
GTCGTCGTCGGGCCCGCCGAAGACTCGTCGGCGCAGGTGCTGACCGCCGAACAGATGATCCTGGTGGCGACCGAATCAGG
TTCGCCCACCTACCTGCTCTACGGCGGTCGGCGGGCCGTGGTGGATCTGGCCGACCCGGCGGTGGTGTGGGCGCTGCGGC
TGCAGGGCCGGGTCCCGCACGTGGTCGCGCAATCGTTGCTCAACGCCGTCCCGGAGGCACCGCGCATCACGGCTCCCCGG
ATTCGTGGCGGCGGGCGGGCCTCGGTCGGGCTGCCCGGGTTTCTGGTCGGCGGTGTGGTGCGCATCACTCGCGCGAGCGG
TGATGAGTATTACGTGGTGCTGGAGGACGGCGTGCAGCGCATCGGCCAGGTCGCCGCGGATTTGTTGCGGTTCGGCGATT
CGCAGGGCAGCGTCAACGTCCCGACGGTGGCCCCCGATGTGATTCGCGTCGCTCCGATCGTGAACACCTTGCCGGTGTCG
GCCTTTCCCGACCGGCCGCCAACACCGGTGGACGGCTCGCCGGGAAGGGCGGTCACCACGTTGTGCGTGACCTGGACGCC
CGCGCAGCCGGGTGCTGCTCGCGTCGCGTTCTTGGCGGGCAGCGGCCCGCCGGTGCCCCTCGGAGGGGTTCCGGTGACAC
TGGCACAAGCCGACGGTCGCGGCCCCGCACTGGACGCGGTGTACCTGCCGCCGGGACGCAGCGCCTACGTAGCCGCGCGC
AGCCTGTCCGGCGGCGGCACCGGCACGCGCTACCTGGTCACCGACACCGGAGTGCGGTTCGCGATCCACGACGACGACGT
GGCACACGACCTCGGTCTGCCGACGGCTGCCATCCCGGCGCCGTGGCCGGTGTTGGCGACACTGCCGTCCGGACCGGAGC
TGAGTAGAGCCAACGCGTCAGTCGCCCGCGATACCGTTGCGCCCGGGCCGTAG

Upstream 100 bases:

>100_bases
CCAGCCGGAGCAAATGTCGGTAGCTGTGGATAGACGGTGAAGAACATGCGTCGCAACGCCTACCGTGGGGAGAAATCAGC
GCGCCACCGTGGGAGAGCCA

Downstream 100 bases:

>100_bases
CCGGCGGCTGGCGGTGGCCAGGGTTGCCATCAGCGCGAGCAGGCAGATCGCGGCACCAGCAAAGGCGGTGTGTAGGGCGC
GGCGATCCGATGGGCCGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component B4; Type VII secretion system protein eccB4; T7SS protein eccB4

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRE
SGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTT
VVVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPR
IRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVS
AFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAAR
SLSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP

Sequences:

>Translated_470_residues
MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRE
SGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTT
VVVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPR
IRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVS
AFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAAR
SLSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
>Mature_469_residues
PSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRES
GALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTV
VVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPRI
RGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVSA
FPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARS
LSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eccB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECCB4_MYCTU (O06317)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   G70564
- RefSeq:   NP_217967.1
- RefSeq:   NP_338082.1
- EnsemblBacteria:   EBMYCT00000001397
- EnsemblBacteria:   EBMYCT00000071490
- GeneID:   887619
- GeneID:   922952
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3556
- KEGG:   mtu:Rv3450c
- TIGR:   MT3556
- TubercuList:   Rv3450c
- GeneTree:   EBGT00050000016351
- HOGENOM:   HBG571250
- OMA:   VMLHDPM
- ProtClustDB:   CLSK792503
- InterPro:   IPR007795

Pfam domain/function: PF05108 DUF690

EC number: NA

Molecular weight: Translated: 48200; Mature: 48068

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c963e54)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAF
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VALLRPQSALGQAPIVMGRESGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELG
HHHHCCHHHCCCCCEEEECCCCEEEEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHCC
HTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTVVVGPAEDSSAQVLTAEQMI
CCCCCCEEECCCCHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECEEE
LVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPR
EEEECCCCCEEEEECCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
IRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNV
CCCCCCCCCCCCHHHHCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEC
PTVAPDVIRVAPIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAG
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEC
SGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARSLSGGGTGTRYLVTDTGVRF
CCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCEEE
AIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
EECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCCH
>Mature Secondary Structure 
PSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAF
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VALLRPQSALGQAPIVMGRESGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELG
HHHHCCHHHCCCCCEEEECCCCEEEEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHCC
HTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTVVVGPAEDSSAQVLTAEQMI
CCCCCCEEECCCCHHHHCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECEEE
LVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPR
EEEECCCCCEEEEECCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
IRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNV
CCCCCCCCCCCCHHHHCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEC
PTVAPDVIRVAPIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAG
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEC
SGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARSLSGGGTGTRYLVTDTGVRF
CCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCEEE
AIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
EECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036