Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 148663306

GI number: 148663306

Start: 3868702

End: 3870048

Strand: Reverse

Name: glmM

Synonym: MRA_3482

Alternate gene names: 148663306

Gene position: 3870048-3868702 (Counterclockwise)

Preceding gene: 148663307

Following gene: 148663305

Centisome position: 87.56

GC content: 69.49

Gene sequence:

>1347_bases
ATGGGTCGACTGTTTGGCACCGATGGTGTGCGCGGTGTCGCCAATCGCGAGTTGACCGCGGAACTGGCCCTGGCACTGGG
CGCCGCGGCGGCGCGACGATTGTCGAGGTCGGGCGCACCGGGTCGGCGAGTCGCGGTGCTTGGCCGCGATCCGCGGGCCA
GCGGCGAGATGCTGGAGGCCGCCGTGATCGCCGGCCTGACCAGTGAGGGCGTCGACGCGCTGCGGGTCGGGGTGTTGCCG
ACCCCCGCGGTGGCCTATCTGACCGGCGCCTACGACGCCGACTTCGGGGTGATGATCTCGGCGTCGCATAACCCGATGCC
CGATAACGGCATCAAAATCTTCGGGCCCGGCGGCCACAAATTAGATGACGACACCGAGGATCAGATCGAGGATCTGGTCC
TCGGCGTCTCCCGCGGACCCGGGTTGCGGCCGGCCGGCGCGGGGATTGGCCGCGTTATCGACGCCGAGGATGCGACCGAA
CGCTACCTGCGCCACGTGGCCAAGGCCGCCACCGCCCGGCTCGATGACCTGGCCGTGGTGGTCGACTGCGCTCATGGGGC
CGCGTCGTCGGCGGCTCCGCGCGCCTACCGAGCGGCCGGTGCCCGGGTTATCGCGATCAACGCCGAACCCAACGGACGCA
ACATCAACGACGGCTGTGGATCGACTCACCTTGACCCGCTGCGGGCAGCGGTGCTCGCCCATCGGGCCGACCTGGGCCTG
GCCCATGATGGAGACGCCGATCGGTGCCTGGCCGTCGACGCCAACGGTGACCTCGTCGACGGTGACGCCATCATGGTGGT
GCTGGCGCTGGCAATGAAAGAGGCCGGTGAGTTGGCCTGCAACACATTGGTGGCCACCGTGATGAGTAACCTCGGGCTGC
ACCTAGCCATGCGCTCGGCCGGCGTCACCGTGCGTACAACCGCCGTCGGTGACCGCTACGTCCTCGAAGAGCTGCGGGCC
GGTGACTACAGCCTCGGAGGCGAACAATCCGGCCACATCGTCATGCCGGCGCTGGGCTCCACCGGTGACGGCATCGTCAC
CGGGCTGCGGTTGATGACCCGCATGGTGCAGACCGGCTCGTCGTTGTCCGACCTGGCGTCGGCGATGCGGACGTTGCCGC
AGGTGCTGATCAACGTCGAGGTTGTCGACAAGGCCACCGCCGCCGCGGCGCCCTCGGTCCGAACGGCGGTCGAGCAGGCC
GCGGCCGAGCTGGGTGACACGGGTCGAATCCTCTTGCGCCCGTCCGGAACTGAGCCGATGATTCGGGTGATGGTGGAGGC
AGCCGACGAGGGCGTCGCCCAGCGGCTGGCGGCCACGGTCGCCGACGCGGTGAGCACCGCGCGCTGA

Upstream 100 bases:

>100_bases
CATGTTTGTGTGCGCTCGTCGGCGTGTCGGTGAACCAACAGGCATATTCGCTGCCAAGAGTGGATATGTGCGCAGCCGTC
AACTGTGAAAGGTTGTCCGT

Downstream 100 bases:

>100_bases
ACCGGAAATGCTGGAACCCCGACGCGGCGCGGGGCGTCCGAATAGGCATGAGACCCGATAGCGTAAACAGCGCCGGCATA
GACATAGCAGCGGTATACGC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLP
TPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATE
RYLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGL
AHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRA
GDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQA
AAELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR

Sequences:

>Translated_448_residues
MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLP
TPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATE
RYLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGL
AHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRA
GDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQA
AAELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR
>Mature_447_residues
GRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLPT
PAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATER
YLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGLA
HDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRAG
DYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAA
AELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=453, Percent_Identity=44.3708609271523, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=27.4944567627494, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_MYCBO (Q7TWH9)

Other databases:

- EMBL:   BX248346
- RefSeq:   NP_857111.1
- ProteinModelPortal:   Q7TWH9
- SMR:   Q7TWH9
- EnsemblBacteria:   EBMYCT00000015324
- GeneID:   1091066
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3471c
- GeneTree:   EBGT00050000015909
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14318
- BioCyc:   MBOV233413:MB3471C-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 45874; Mature: 45742

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
AVIAGLTSEGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHK
HHHHCCCCCCCHHEEECCCCCCHHHHEECCCCCCCCEEEECCCCCCCCCCEEEECCCCCC
LDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATERYLRHVAKAATARLDDLAVV
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCEEEE
VDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGL
EECCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
AHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSA
CCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GVTVRTTAVGDRYVLEELRAGDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGS
CCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
SLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAAAELGDTGRILLRPSGTEPM
CHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHH
IRVMVEAADEGVAQRLAATVADAVSTAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
AVIAGLTSEGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHK
HHHHCCCCCCCHHEEECCCCCCHHHHEECCCCCCCCEEEECCCCCCCCCCEEEECCCCCC
LDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATERYLRHVAKAATARLDDLAVV
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCEEEE
VDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGL
EECCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
AHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSA
CCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GVTVRTTAVGDRYVLEELRAGDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGS
CCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
SLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAAAELGDTGRILLRPSGTEPM
CHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHH
IRVMVEAADEGVAQRLAATVADAVSTAR
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972