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The map label for this gene is lytB1

Identifier: 148663245

GI number: 148663245

Start: 3805571

End: 3806560

Strand: Reverse

Name: lytB1

Synonym: MRA_3422

Alternate gene names: 148663245

Gene position: 3806560-3805571 (Counterclockwise)

Preceding gene: 148663246

Following gene: 148663244

Centisome position: 86.12

GC content: 62.83

Gene sequence:

>990_bases
ATGGCTGAGGTGTTCGTGGGACCGGTCGCACAGGGATACGCTTCGGGTGAAGTCACGGTGCTGTTGGCGTCGCCGCGGTC
GTTTTGCGCCGGTGTAGAGCGTGCTATCGAGACGGTCAAGCGAGTGCTTGACGTGGCCGAAGGCCCGGTGTATGTGCGCA
AGCAAATCGTGCACAACACTGTTGTGGTTGCCGAGTTGCGGGACCGGGGAGCAGTGTTCGTCGAGGATCTCGACGAGATT
CCCGATCCGCCGCCGCCGGGGGCGGTCGTGGTGTTCTCCGCGCATGGGGTTTCCCCGGCGGTGCGCGCGGGCGCTGATGA
GCGGGGACTGCAGGTCGTCGACGCGACCTGCCCACTGGTGGCGAAAGTCCACGCTGAAGCCGCACGGTTTGCCGCGCGCG
GTGACACGGTGGTCTTCATCGGGCACGCCGGACATGAGGAGACCGAAGGCACGCTTGGCGTCGCTCCGCGGTCAACATTA
TTGGTGCAGACACCCGCTGATGTGGCAGCGTTGAACCTGCCCGAGGGTACCCAGCTATCGTATCTGACCCAGACAACCCT
GGCACTTGATGAAACTGCCGATGTCATTGATGCGCTGCGCGCGAGGTTTCCGACGTTGGGCCAACCCCCCTCTGAAGACA
TCTGCTATGCCACCACGAACAGACAGCGTGCGCTGCAATCGATGGTCGGTGAATGTGACGTTGTGTTGGTGATTGGCTCG
TGCAATTCGTCGAATTCGCGGCGTCTGGTCGAGTTGGCGCAGCGAAGTGGGACGCCGGCCTACTTGATTGACGGGCCTGA
TGACATTGAGCCCGAATGGCTGTCGTCGGTCTCGACGATCGGTGTCACCGCGGGAGCCTCCGCGCCGCCACGACTGGTGG
GGCAGGTGATTGATGCACTTCGCGGATACGCCTCGATCACCGTGGTGGAACGCTCGATAGCGACCGAGACGGTGCGATTC
GGCCTTCCCAAACAGGTTCGCGCGCAATGA

Upstream 100 bases:

>100_bases
CCGATGAACGCATCCAGGCTGCTATTGCGGCACTGCCCGATGCGGTGCGATCCCCAGACCTGATCGCGTTGTCGCAACTG
ATATGTCGCCGGGAGTGCTG

Downstream 100 bases:

>100_bases
CAACCACGATTCGCAACGGACGCGGGGACTTGATTTGAACCGCCCCGGCATGTCCGGAGACTCCAGTTCTTGGAAAGGAT
GGGGTCATGTCAGGTGGTTC

Product: putative lytB-related protein LytB1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNTVVVAELRDRGAVFVEDLDEI
PDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLVAKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTL
LVQTPADVAALNLPEGTQLSYLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGS
CNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDALRGYASITVVERSIATETVRF
GLPKQVRAQ

Sequences:

>Translated_329_residues
MAEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNTVVVAELRDRGAVFVEDLDEI
PDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLVAKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTL
LVQTPADVAALNLPEGTQLSYLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGS
CNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDALRGYASITVVERSIATETVRF
GLPKQVRAQ
>Mature_328_residues
AEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNTVVVAELRDRGAVFVEDLDEIP
DPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLVAKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTLL
VQTPADVAALNLPEGTQLSYLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGSC
NSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDALRGYASITVVERSIATETVRFG
LPKQVRAQ

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family

Homologues:

Organism=Escherichia coli, GI1786212, Length=313, Percent_Identity=50.7987220447284, Blast_Score=313, Evalue=7e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISPH2_MYCBO (P0A5I3)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_857055.1
- EnsemblBacteria:   EBMYCT00000016587
- GeneID:   1090957
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3414c
- GeneTree:   EBGT00050000016858
- HOGENOM:   HBG335228
- OMA:   REENIEF
- ProtClustDB:   CLSK799986
- BioCyc:   MBOV233413:MB3414C-MONOMER
- BRENDA:   1.17.1.2
- HAMAP:   MF_00191
- InterPro:   IPR003451
- TIGRFAMs:   TIGR00216

Pfam domain/function: PF02401 LYTB

EC number: =1.17.1.2

Molecular weight: Translated: 34667; Mature: 34535

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNT
CCCEEECCHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCE
VVVAELRDRGAVFVEDLDEIPDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLV
EEEEEECCCCCEEEHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEECCCCHH
AKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTLLVQTPADVAALNLPEGTQLS
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEECCCCEEEEECCCCCEEEECCCCCEEE
YLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEEC
CNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDAL
CCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
RGYASITVVERSIATETVRFGLPKQVRAQ
HCCCEEEEEHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
AEVFVGPVAQGYASGEVTVLLASPRSFCAGVERAIETVKRVLDVAEGPVYVRKQIVHNT
CCEEECCHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCE
VVVAELRDRGAVFVEDLDEIPDPPPPGAVVVFSAHGVSPAVRAGADERGLQVVDATCPLV
EEEEEECCCCCEEEHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEECCCCHH
AKVHAEAARFAARGDTVVFIGHAGHEETEGTLGVAPRSTLLVQTPADVAALNLPEGTQLS
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEECCCCEEEEECCCCCEEEECCCCCEEE
YLTQTTLALDETADVIDALRARFPTLGQPPSEDICYATTNRQRALQSMVGECDVVLVIGS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEEC
CNSSNSRRLVELAQRSGTPAYLIDGPDDIEPEWLSSVSTIGVTAGASAPPRLVGQVIDAL
CCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
RGYASITVVERSIATETVRFGLPKQVRAQ
HCCCEEEEEHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972