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The map label for this gene is ygjG [C]

Identifier: 148663193

GI number: 148663193

Start: 3725233

End: 3726549

Strand: Direct

Name: ygjG [C]

Synonym: MRA_3371

Alternate gene names: 148663193

Gene position: 3725233-3726549 (Clockwise)

Preceding gene: 148663191

Following gene: 148663194

Centisome position: 84.28

GC content: 65.53

Gene sequence:

>1317_bases
TTGCACTTCGCCCGGCACGGTGCCGGCATCCAACACCCGGTCATCGTCCGCGGCGACGGCGTCACCATCTTCGACGACCG
CGGCAAGAGCTATCTGGACGCCTTGTCCGGGCTGTTCGTGGTGCAGGTCGGTTACGGCCGGGCCGAACTCGCCGAGGCGG
CCGCGCGGCAAGCCGGCACGCTGGGGTATTTCCCGCTCTGGGGGTATGCCACCCCGCCGGCGATCGAGCTCGCCGAGCGC
CTGGCCCGCTACGCGCCCGGGGACCTAAACCGGGTGTTTTTCACCAGCGGCGGCACCGAGGCCGTCGAAACCGCCTGGAA
GGTGGCCAAGCAGTACTTCAAGCTCACCGGCAAACCGGGCAAACAAAAGGTCATTTCACGCTCGATCGCCTACCACGGCA
CCACCCAGGGCGCGCTGGCGATCACCGGCCTGCCATTGTTCAAGGCGCCATTCGAACCGCTGACGCCGGGCGGCTTCCGG
GTGCCCAACACCAATTTCTACCGAGCACCGTTGCACACCGACCTCAAAGAGTTCGGGCGATGGGCTGCTGACCGGATCGC
CGAGGCCATCGAGTTCGAAGGCCCCGACACCGTGGCCGCGGTGTTTTTGGAGCCGGTGCAGAACGCGGGCGGCTGCATCC
CGGCGCCGCCGGGTTATTTCGAACGGGTCCGCGAGATCTGTGACCGCTACGACGTGCTGCTGGTCTCCGACGAGGTGATC
TGTGCGTTCGGCCGGATCGGGTCGATGTTCGCCTGTGAAGACCTCGGCTACGTGCCCGACATGATCACCTGCGCCAAGGG
CCTGACGTCGGGCTACTCGCCGCTGGGCGCGATGATCGCCAGCGACCGGTTGTTCGAACCGTTCAACGACGGCGAGACGA
TGTTCGCACACGGCTACACGTTTGGCGGTCATCCGGTGTCGGCGGCCGTCGGCCTGGCCAACCTCGACATCTTCGAGCGC
GAGGGTCTCAGCGATCACGTCAAGCGGAATTCCCCCGCGCTGCGGGCCACCCTGGAGAAACTGTACGACCTGCCCATCGT
CGGCGACATCCGCGGCGAGGGGTATTTCTTCGGCATCGAACTGGTCAAAGACCAGGCGACCAAGCAAACCTTCACCGATG
ACGAACGCGCACGACTGCTAGGCCAGGTATCCGCGGCGCTCTTTGAGGCCGGGCTGTACTGCCGCACCGACGACCGCGGG
GACCCCGTCGTCCAGGTGGCTCCCCCGCTGATTAGCGGACAGCCCGAGTTCGACACCATCGAAACCATCCTGCGCAGCGT
GCTCACCGACACCGGACGCAAATATCTTCATCTGTAA

Upstream 100 bases:

>100_bases
ATGAGATGCTGTCGCAGTGCCTCGAATTCGGAAACCTCCATCGAGGTCATTGCCCGAGCCTAGCGCTGCGCTCGCCAACA
CGACGACACGAAACCTTTGG

Downstream 100 bases:

>100_bases
CTTTCGTCCCGCCAGTCACAGCGCGGCTCCTCGCGGTCGGGCCGCCGATCACCTACTCTGCACAGACGATGGCCTTCTTA
CGTTCGGTATCGTGCCTGGC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIELAER
LARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFR
VPNTNFYRAPLHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVI
CAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFER
EGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRG
DPVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL

Sequences:

>Translated_438_residues
MHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIELAER
LARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFR
VPNTNFYRAPLHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVI
CAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFER
EGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRG
DPVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL
>Mature_438_residues
MHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIELAER
LARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFR
VPNTNFYRAPLHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVI
CAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFER
EGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRG
DPVVQVAPPLISGQPEFDTIETILRSVLTDTGRKYLHL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI24119277, Length=431, Percent_Identity=29.6983758700696, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI37574042, Length=432, Percent_Identity=29.1666666666667, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13994255, Length=447, Percent_Identity=27.2930648769575, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI226442705, Length=434, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI226442709, Length=372, Percent_Identity=29.5698924731183, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4557809, Length=433, Percent_Identity=27.9445727482679, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI284507298, Length=335, Percent_Identity=28.0597014925373, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI145693181, Length=363, Percent_Identity=34.9862258953168, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789759, Length=352, Percent_Identity=32.3863636363636, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789016, Length=368, Percent_Identity=31.25, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788044, Length=405, Percent_Identity=28.641975308642, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1786991, Length=347, Percent_Identity=31.4121037463977, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.0476190476191, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786349, Length=354, Percent_Identity=25.1412429378531, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=30.1801801801802, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI25144271, Length=425, Percent_Identity=26.8235294117647, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=24.8858447488584, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=306, Percent_Identity=27.4509803921569, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=381, Percent_Identity=23.0971128608924, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=359, Percent_Identity=28.6908077994429, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323470, Length=438, Percent_Identity=25.7990867579909, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=321, Percent_Identity=30.5295950155763, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI161085790, Length=386, Percent_Identity=30.0518134715026, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI28574759, Length=375, Percent_Identity=30.1333333333333, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21356575, Length=437, Percent_Identity=28.8329519450801, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21357415, Length=431, Percent_Identity=27.3781902552204, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366494, Length=388, Percent_Identity=25.5154639175258, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667139, Length=388, Percent_Identity=25.5154639175258, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667143, Length=388, Percent_Identity=25.5154639175258, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47718; Mature: 47718

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGT
CCCCCCCCCCCCCEEEECCCEEEECCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCC
LGYFPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPG
CCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
KQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAPLHTDLKEFGR
HHHHHHHHHHHCCCCCCCEEEECCCHHCCCCCCCCCCCEECCCCCEEECCCHHHHHHHHH
WAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVI
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCHHH
CAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYT
HHHHCCCCEEEHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
FGGHPVSAAVGLANLDIFEREGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIE
CCCCCHHHHHHHHHCCHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEE
LVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTI
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCCCHHHH
ETILRSVLTDTGRKYLHL
HHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MHFARHGAGIQHPVIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGT
CCCCCCCCCCCCCEEEECCCEEEECCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCC
LGYFPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYFKLTGKPG
CCCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
KQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAPLHTDLKEFGR
HHHHHHHHHHHCCCCCCCEEEECCCHHCCCCCCCCCCCEECCCCCEEECCCHHHHHHHHH
WAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERVREICDRYDVLLVSDEVI
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEECCHHH
CAFGRIGSMFACEDLGYVPDMITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYT
HHHHCCCCEEEHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
FGGHPVSAAVGLANLDIFEREGLSDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIE
CCCCCHHHHHHHHHCCHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEE
LVKDQATKQTFTDDERARLLGQVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTI
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCCCHHHH
ETILRSVLTDTGRKYLHL
HHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]