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The map label for this gene is serB2 [H]

Identifier: 148662895

GI number: 148662895

Start: 3414103

End: 3415332

Strand: Reverse

Name: serB2 [H]

Synonym: MRA_3074

Alternate gene names: 148662895

Gene position: 3415332-3414103 (Counterclockwise)

Preceding gene: 148662896

Following gene: 148662894

Centisome position: 77.27

GC content: 66.1

Gene sequence:

>1230_bases
ATGCCAGCCAAGGTGTCGGTGCTGATCACGGTCACCGGCATGGATCAGCCAGGCGTGACATCCGCGCTCTTCGAGGTGCT
CGCGCAGCACGGAGTCGAGCTGCTCAACGTCGAACAAGTGGTGATCCGGGGCCGGCTCACGCTGGGTGTGCTGGTGTCGT
GCCCGCTGGACGTTGCCGACGGTACCGCGCTGCGCGACGACGTCGCGGCCGCCATCCACGGGGTGGGTCTAGACGTCGCC
ATCGAGCGCAGCGACGATCTGCCAATCATTCGGCAACCGTCCACCCACACCATTTTCGTGCTGGGACGCCCGATTACCGC
CGGAGCGTTCAGCGCGGTGGCCAGGGGAGTGGCCGCACTCGGCGTCAACATCGACTTCATCCGCGGCATTTCCGACTACC
CGGTCACCGGCCTGGAGTTGCGGGTCTCGGTGCCGCCTGGATGCGTGGGTCCGCTGCAGATCGCCCTGACCAAGGTGGCC
GCCGAAGAGCATGTCGATGTGGCCGTCGAGGACTACGGCTTGGCTTGGCGCACCAAACGCCTGATCGTCTTCGACGTCGA
CTCCACTCTGGTCCAAGGCGAGGTCATCGAGATGCTGGCAGCCCGTGCGGGTGCCCAGGGACAGGTCGCCGCGATCACCG
AGGCCGCGATGCGTGGTGAGCTGGACTTCGCCGAGTCGCTGCAGCGTCGTGTTGCCACCTTGGCGGGGCTGCCCGCGACG
GTGATAGACGACGTCGCCGAGCAGCTCGAACTGATGCCCGGTGCTCGGACCACGATCCGGACCTTGCGGCGTCTGGGTTT
TCGCTGCGGTGTGGTTTCCGGCGGCTTTCGGCGGATCATCGAGCCGCTCGCACGCGAGTTGATGTTGGATTTCGTTGCGT
CCAACGAGCTGGAAATCGTCGATGGCATTCTTACCGGCCGGGTCGTGGGGCCGATTGTTGACCGGCCCGGCAAGGCCAAG
GCGCTTCGGGACTTCGCGAGCCAGTATGGGGTGCCGATGGAGCAGACCGTCGCGGTCGGCGACGGCGCCAACGATATCGA
CATGCTGGGCGCGGCCGGGCTGGGAATAGCATTCAACGCCAAGCCGGCGTTGCGTGAGGTCGCCGATGCGTCGTTGAGCC
ATCCGTACCTGGACACGGTGTTGTTCTTGTTGGGCGTGACTCGCGGTGAGATCGAGGCCGCCGACGCCGGCGACTGTGGG
GTGCGTCGCGTCGAAATCCCGGCCGACTAG

Upstream 100 bases:

>100_bases
CTTCGCGCCGAGGCCCACGTCGGGCGTCATCATGACGAGCCCGCCATGGTGACTTCGAGCTGATGGGGCCGTACCGGTTG
GGCCCCATCTGAAGGTGAGC

Downstream 100 bases:

>100_bases
GTTGCTCGCGGAGCATGCGGCACGATAGTCGGGTGCTCGACAACGGCGGCCCTGATGCGGCTGACCCCGACCTGCTGATC
GACTTCCGAAACGTGTCCCT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVA
IERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVA
AEEHVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPAT
VIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAK
ALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCG
VRRVEIPAD

Sequences:

>Translated_409_residues
MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVA
IERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVA
AEEHVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPAT
VIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAK
ALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCG
VRRVEIPAD
>Mature_408_residues
PAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVAI
ERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAA
EEHVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPATV
IDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAKA
LRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCGV
RRVEIPAD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1790849, Length=235, Percent_Identity=46.8085106382979, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321647, Length=243, Percent_Identity=41.5637860082305, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43059; Mature: 42928

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVAD
CCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECHHHHHHHCCCEEEEEEECCCCCCC
GTALRDDVAAAIHGVGLDVAIERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAAL
CCHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHH
GVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
CCCHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEEEE
LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPAT
EEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
VIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIV
HHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
DGILTGRVVGPIVDRPGKAKALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNA
HHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHCCCCCCEEECC
KPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCGVRRVEIPAD
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCC
>Mature Secondary Structure 
PAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVAD
CCEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECHHHHHHHCCCEEEEEEECCCCCCC
GTALRDDVAAAIHGVGLDVAIERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAAL
CCHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHH
GVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKR
CCCHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEEEE
LIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPAT
EEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHH
VIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIV
HHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
DGILTGRVVGPIVDRPGKAKALRDFASQYGVPMEQTVAVGDGANDIDMLGAAGLGIAFNA
HHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHCCCCCCEEECC
KPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAGDCGVRRVEIPAD
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA