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The map label for this gene is PE_PGRS44 [H]

Identifier: 148662430

GI number: 148662430

Start: 2933489

End: 2935150

Strand: Direct

Name: PE_PGRS44 [H]

Synonym: MRA_2620

Alternate gene names: 148662430

Gene position: 2933489-2935150 (Clockwise)

Preceding gene: 148662429

Following gene: 148662434

Centisome position: 66.37

GC content: 72.86

Gene sequence:

>1662_bases
GTGTCACATGACGGGTTGGGAGGGTGGCTGATGTCGTTTGTCACGGCAGCTCCAGAGATGCTGGCGACGGCGGCGCAGAA
TGTCGCGAATATCGGCACATCGCTGAGTGCGGCAAACGCGACGGCAGCGGCGTCCACGACCTCGGTGCTGGCGGCCGGAG
CCGACGAGGTATCGCAGGCTATCGCAAGGCTGTTCAGTGATTACGCCACGCACTATCAGTCGCTGAACGCTCAAGCCGCG
GCATTTCATCACAGCTTCGTGCAAACGTTGAACGCCGCCGGTGGCGCCTATTCGAGCGCCGAGGCGGCCAACGCTTCGGC
GCAGGCGTTGGAACAGAATCTGTTGGCCGTGATCAATGCGCCCGCCCAGGCGTTGTTCGGGCGTCCCCTGATCGGCAATG
GCGCGAATGGAACAGCGGCCAGCCCCAACGGCGGTGATGGTGGGATTTTGTACGGCAACGGCGGCAACGGCTTCTCCCAA
ACGACCGCCGGGGTGGCCGGCGGCGCCGGTGGTTCCGCGGGCCTGATCGGCAACGGCGGCAATGGTGGCGCCGGTGGGGC
CGGTGCTGCCGGCGGGGCCGGCGGCGCCGGCGGATGGCTGCTCGGCAACGGTGGCGCCGGCGGTCCCGGCGGCCCAACGG
ACGTTCCTGCCGGCACAGGTGGAGCCGGCGGGGCCGGCGGCGACGCCCCATTGATCGGCTGGGGCGGCAACGGCGGGCCC
GGCGGTTTCGCTGCTTTTGGAAACGGTGGGGCCGGCGGCAACGGCGGCGCCAGCGGTTCGCTCTTTGGCGTCGGCGGCGC
CGGCGGCGTCGGCGGATCGAGCGAAGACGTCGGCGGCACCGGCGGGGCCGGCGGCGCTGGCCGCGGTCTATTCCTTGGCC
TGGGCGGTGATGGCGGCGCCGGCGGCACCAGCAACAACAACGGCGGTGACGGTGGCGCCGGCGGCACCGCGGGAGGTCGA
TTGTTCAGCCTGGGCGGTGACGGTGGCAACGGTGGTGCCGGTACCGCAATCGGATCCAACGCCGGTGACGGTGGCGCCGG
CGGTGACAGCAGCGCCCTGATCGGCTACGCCCAGGGCGGCTCCGGCGGCCTCGGCGGCTTCGGCGAAAGTACCGGCGGCG
ACGGCGGCCTGGGCGGCGCCGGCGCTGTGCTCATCGGCACGGGCGTCGGCGGTTTCGGCGGCCTCGGTGGCGGCTCCAAC
GGCACCGGGGGCGCGGGCGGCGCGGGCGGCACGGGCGCCACGCTGATCGGCCTGGGCGCCGGCGGCGGCGGCGGCATCGG
CGGGTTCGCCGTCAACGTGGGCAACGGCGTCGGCGGTCTGGGCGGCCAGGGCGGCCAGGGCGCCGCGCTGATCGGCCTGG
GCGCCGGCGGTGCCGGCGGTGCCGGCGGCGCCACAGTCGTTGGACTTGGTGGCAATGGCGGTGACGGCGGTGACGGTGGC
GGCCTGTTTAGTATCGGCGTCGGTGGGGACGGCGGCAACGCCGGCAACGGCGCCATGCCTGCCAATGGCGGCAACGGCGG
CAACGCCGGGGTCATTGCCAACGGCTCCTTTGCCCCGTCGTTCGTCGGCTTCGGCGGCAACGGCGGCAACGGCGTCAATG
GCGGCACCGGCGGCAGCGGCGGGATCCTTTTTGGCGCCAACGGCGCGAACGGACCGTCGTAG

Upstream 100 bases:

>100_bases
ACGCCCAGTTCGCCTATGAGAAGGCAGTAAGAAGCGCGAAAAATGGCAGACCCCGACGGAGGCCCTCTGAAAGAGTCTTG
ATCATCAGGGCGCGTGACAT

Downstream 100 bases:

>100_bases
CGGGTCCTCCAGCGCACTACTCGAACAACCCCGGTTGACTCGCTCCGACCGGTGGCGTCATGCCCAGGTGCGTCCAGGCC
AGGGCGGTGGCCACCCGGCC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MSHDGLGGWLMSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAA
AFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQ
TTAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGP
GGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGR
LFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSN
GTGGAGGAGGTGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGG
GLFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS

Sequences:

>Translated_553_residues
MSHDGLGGWLMSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAA
AFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQ
TTAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGP
GGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGR
LFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSN
GTGGAGGAGGTGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGG
GLFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS
>Mature_552_residues
SHDGLGGWLMSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAA
FHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQT
TAGVAGGAGGSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPG
GFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRL
FSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNG
TGGAGGAGGTGATLIGLGAGGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGGG
LFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSGGILFGANGANGPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 47342; Mature: 47211

Theoretical pI: Translated: 3.74; Mature: 3.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDGLGGWLMSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
IARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHEECC
PAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCC
NGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGP
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
GGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGA
CCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GGTSNNNGGDGGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGG
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
SGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGG
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCC
GLFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSG
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCC
GILFGANGANGPS
CEEEECCCCCCCC
>Mature Secondary Structure 
SHDGLGGWLMSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
IARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHEECC
PAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCC
NGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGP
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
GGFAAFGNGGAGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGA
CCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
GGTSNNNGGDGGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGG
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
SGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GGGGGIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNGGDGGDGG
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCC
GLFSIGVGGDGGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGSG
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCC
GILFGANGANGPS
CEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]