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The map label for this gene is 148662087

Identifier: 148662087

GI number: 148662087

Start: 2548604

End: 2549833

Strand: Direct

Name: 148662087

Synonym: MRA_2285

Alternate gene names: NA

Gene position: 2548604-2549833 (Clockwise)

Preceding gene: 148662085

Following gene: 148662088

Centisome position: 57.66

GC content: 67.56

Gene sequence:

>1230_bases
GTGGGTGCGAACGGTGATGTCGCGTTGAGCCGCATCGGCGCCACCCGTCCGGCATTGAGCGCGTGGCGATTCGTCACAGT
GTTCGGGGTGGTCGGCCTGCTCGCCGACGTCGTGTATGAAGGGGCCCGTTCGATCACCGGCCCGCTGCTGGCTTCGTTGG
GAGCGACCGGACTGGTGGTCGGAGTCGTCACCGGCGTCGGTGAGGCCGCCGCCTTGGGCTTGCGGCTGGTGTCGGGGCCA
TTGGCCGATCGAAGCCGACGGTTTTGGGCCTGGACCATCGCCGGCTACACCCTGACGGTGGTAACGGTTCCGCTGCTCGG
CATCGCGGGCGCCCTGTGGGTGGCGTGCGCGTTGGTCATCGCCGAGCGAGTCGGGAAAGCTGTGCGCGGCCCCGCCAAAG
ACACCCTGCTGTCGCACGCGGCCAGTGTGACCGGCCGAGGCCGCGGTTTCGCCGTGCACGAGGCGCTGGACCAGGTCGGT
GCGATGATCGGCCCTCTCACCGTTGCCGGGATGCTCGCGATCACCGGGAATGCCTATGCGCCCGCGCTCGGCGTGCTGAC
CCTGCCCGGCGGTGCCGCCCTTGCTCTGTTGCTGTGGCTGCAGCGTCGGGTGCCCCGCCCGGAGTCCTACGAGGACTGTC
CGGTTGTCCTCGGTAATCCTTCGGCGCCGCGACCCTGGGCGCTGCCGGCGCAGTTCTGGCTGTACTGCGGGTTCACCGCG
ATCACCATGCTGGGGTTTGGCACGTTCGGGTTGCTGTCGTTTCACATGGTCAGCCACGGCGTGCTGGCCGCCGCCATGGT
CCCGGTGGTCTATGCGGCCGCAATGGCCGCAGATGCGCTGACGGCCTTGGCCTCAGGCTTCAGCTATGACAGATATGGCG
CGAAAACCCTTGCCGTTCTGCCGATTCTGTCGATTCTGGTGGTGCTATTCGCCTTCACGGACAACGTCACAATGGTGGTC
ATTGGCACGTTGGTGTGGGGCGCAGCGGTCGGAATACAAGAGTCCACGCTGCGCGGCGTGGTGGCCGACCTGGTCGCCAG
CCCACGGCGGGCCAGCGCCTACGGCGTGTTCGCCGCAGGGCTGGGCGCTGCGACCGCCGGGGGCGGCGCCCTCATCGGCT
GGCTGTACGACATCTCCATCGGCACGCTCGTTGTGGTGGTGATCGCACTTGAACTGATGGCCCTGGTGATGATGTTCGCG
ATCCGACTACCCCGCGTAGCACCGAGCTAA

Upstream 100 bases:

>100_bases
AGCCGTGTTGAGAAATGAGTTCGGCCGTCGGCAGCAACCTCCCCACTCAGCAATCCCAGCTTCACCCTAAACCTGGCGTT
CGTACGCCACCTAGCATCTG

Downstream 100 bases:

>100_bases
AGAAGCGATCAGGCGGCCCAACGGAACAGCAGGTTGGTATGCGACAACATGCTTGACCGGCACGCCAACAAGCACGACTG
CCACCGATCCAGGTAAGTGG

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGP
LADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVG
AMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTA
ITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVV
IGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFA
IRLPRVAPS

Sequences:

>Translated_409_residues
MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGP
LADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVG
AMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTA
ITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVV
IGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFA
IRLPRVAPS
>Mature_408_residues
GANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGPL
ADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGA
MIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTAI
TMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVVI
GTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAI
RLPRVAPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2265_MYCTU (P64961)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   E70729
- RefSeq:   NP_216781.1
- RefSeq:   NP_336795.1
- ProteinModelPortal:   P64961
- EnsemblBacteria:   EBMYCT00000001449
- EnsemblBacteria:   EBMYCT00000072678
- GeneID:   887976
- GeneID:   924099
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2327
- KEGG:   mtu:Rv2265
- TIGR:   MT2327
- TubercuList:   Rv2265
- GeneTree:   EBGT00050000014791
- HOGENOM:   HBG575542
- OMA:   ADATYEG
- ProtClustDB:   CLSK791734
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 41891; Mature: 41760

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f9ec58c)-; HASH(0x1f7a5518)-; HASH(0x1fc85a70)-; HASH(0x1fc795a8)-; HASH(0x1fcbe3c8)-; HASH(0x1f083334)-; HASH(0x1e13dd5c)-; HASH(0x1fc39a38)-; HASH(0x1fc47060)-; HASH(0x1ad11c0c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVV
CCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVI
HHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
AERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYA
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTA
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
ITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHH
PILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHC
LGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAIRLPRVAPS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
GANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVV
CCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVI
HHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
AERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYA
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTA
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
ITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHH
PILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHC
LGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAIRLPRVAPS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036